Fig 1: Apremilast’s impact on ELISA assay of renal cleaved caspase-3 (A), RT-PCR of Bax (B), and Bcl-2 (C) gene expression. The mean ± standard deviation (n = 6). A significant difference was analyzed by one-way ANOVA, followed by the Tukey–Kramer post-analysis test. A statistically significant value is P < 0.05. Two significant differences as compared to the other groups are: (a) the control group and (b) the MTX group. Bax: Bcl-2 associated X, Bcl-2: B-cell lymphoma 2
Fig 2: Renal tissue levels of cleaved caspase-3. Data are expressed as mean ± SD (n = 6). Statistical significance is set at P < 0.05, as determined by one-way ANOVA followed by the Tukey-Kramer post-hoc test. (a) significant difference relative to the sham group; (b) significant difference relative to the CLP group. CLP: cecal ligation-puncture.
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