Fig 1: The serum-based antibodies treatment reverses the expression of p53, Bcl-xL, NF-κB, and Bax.ELISA analysis revealed the changes in the expression of p53, Bcl-xL, NF-κB, and Bax proteins before and after serum treatment. The tumor volume reached its peak at week 12. The mice in the tumor + serum treatment group received serum treatment at weeks 15, 16, and 17, respectively. Results are presented as the mean ± standard deviation (SD) obtained from at least three biological replicates. Statistical significance was determined by a paired two-tailed t-test. Asterisks indicate the following: **p<0.01. Figure 3—source data 1.Excel file of ELISA analysis data for p53, Bcl-xL, NF-κB, and Bax expression is shown in Figure 3.