Fig 1: Effects of DLE and MC on serum and skin IL-31 levels in compound 48/80 or chloroquine-injected ICR mice. (A) Serum IL-31 levels in the compound 48/80-injected group. (B) Serum IL-31 levels in the chloroquine-injected group. (C) IL-31 expression in dorsal skin tissue of compound 48/80-injected group. (D) IL-31 expression in dorsal skin tissue of chloroquine-injected group. IL-31 levels were measured using ELISA and western blot. Each bar represents the mean ± SD (n=5). #P<0.05 vs. normal group. *P<0.05 vs. control group. DLE, D. lotus leaf extract; MC, myricitrin; IL-31, interleukin-31.