Fig 1: Representative immunohistological images showing SR-B1 (a,b), LOX-1 (c,d), and CD68 (e,f) expression in ethmoid sinus mucosa sampled from a CRSwNP patient. Vascular endothelial cells (arrowheads) are stained positively both for SR-B1 and LOX-1. In contrast, numerous submucosal inflammatory cells show intense positive staining for LOX-1 compared to that for SR-B1. Scale bar: 20 µm.
Fig 2: Comparison of mRNA expression in paranasal sinus mucosa from the controls, and CRSsNP and CRSwNP patients as detected by RT-PCR. (a) scavenger receptor class B type 1 (SR-B1) and (b) lectin-like oxidized LDL receptor-1 (LOX-1) mRNA levels were quantitatively normalized to the glyceraldehyde 3-phosphate dehydrogenase (GAPDH) mRNA levels. Center lines: median values. Boxes: interquartile ranges. Error bars: overall ranges. NS: not significant.
Fig 3: Correlation between the severity of computed tomography (CT) findings and mRNA expression levels for (a) SR-B1 and (b) LOX-1 in sinus mucosa.
Fig 4: Comparison of tissue levels of LOX-1 protein in paranasal sinus mucosa from controls and CRSsNP and CRSwNP patients as detected by ELISA. Data are mean ± SD.
Supplier Page from Abcam for Human LOX1 ELISA Kit