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Molecular Biology
DNA
pAAV-hsyn-GRAB_DA2m (AAV9)
pAAV-hsyn-GRAB_DA2m (AAV9) from Addgene Inc.
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Citations:
(4)
Supplier Page
Supplier Page from
Addgene Inc. for
pAAV-hsyn-GRAB_DA2m (AAV9)
Description
Synapsin-driven expression of 2nd generation medium affinity dopamine sensor GRAB_rDA2m
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
pAAV-hsyn-GRAB_DA2m (AAV9)
Company
Addgene Inc.
Price
Supplier Page
View Company Product Page
Catalog Number
140553-AAV9
Source/Expression System
Mammalian
Molecule Name
The 2nd generation DA sensor GRAB_DA2m (medium affinity)
Quantity
100 µL
Purity
suitable purity for injection into animals
Species
recombinant adeno-associated virus (rAAV)
Vector Name
pAAV-hsyn-GRAB_DA2m
Promoter
Synapsin
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Addgene Inc.
490 Arsenal Way
Suite 100
Watertown
,
Massachusetts
02472
United States
Phone
: +1 (617) 233-4363
Email: help@addgene.org
Company Profile
Website:
www.addgene.org/
Citations (4)
(1)
The Cellular and Synaptic Actions of Dopamine During Behavior
bioRxiv
August 6, 2026
Mélanie Druart, Yun C. Yang, Nicolas X. Tritsch, Tanya Sippy
photometry
dopamine neuron
manipulation,
mice
received
injections
of either pAAV-hSyn-GRAB_DA2m (
Addgene
#
140553-AAV9
; 2.4×1013 GC/ml, diluted
1:4
; 300 nl) or pAAV-hSyn-GRAB_rDA3m (
BrainVTA
#
PT4746
; 5.65×1012 GC/ml, diluted
(2)
Striatal cholinergic and dopaminergic driven astrocyte Ca 2+ activity is disrupted in Parkinsonian mice
bioRxiv
July 12, 2026
Wesley R. Evans, Hunter G. Wells, Cynthia Jacob, Angelica Vellore, Rafiq Huda
gfaABC1D-cyto-GCaMP6f (
Addgene
,
52925-AAV5
), hSyn-GRAB-ACh3.0 (
Addgene
,
121922-AAV9
), hSyn-GRAB-DA2m (
Addgene
,
140553-AAV9
), hSyn-GRAB-rACh1.7 (
BrainVTA
,
PT-5488
), hSyn-GRAB-rDA1m (
Addgene
,
140556-AAV9
), and CAG-FLEX-rc [Jaws-KCG-tdTomato-ER2]
(3)
The gut-brain vagal axis governs mesolimbic dopamine dynamics and reward events
Science Advances
January 30, 2026
Oriane Onimus, Faustine Arrivet, Tinaïg Le Borgne, Sylvie Perez, Julien Castel, Anthony Ansoult, Benoit Bertrand, Nejmeh Mashhour, Camille de Almeida, Linh-Chi Bui,
et al.
http://n2t.net/addgene:28306; RRID: Addgene_28306). pAAV-hsyn-GRAB_DA2m was a gift from Y. Li (
Addgene
, viral prep #
140553-AAV9
; http://n2t.net/addgene:140553; RRID: Addgene_140553). pENN.AAV.CamKII.GCaMP6f.WPRE.SV40 was a gift
(4)
Dopamine pathways mediating affective state transitions after sleep loss
Neuron
January 3, 2024
Mingzheng Wu, Xin Zhang, Sihan Feng, Sara N. Freda, Pushpa Kumari, Vasin Dumrongprechachan, Yevgenia Kozorovitskiy
DA transients,
mice
were transduced with AAV9.hSyn.GRAB.DA2m (1.7 x 1013 GC/ml,
Addgene
viral prep #
140553-AAV9
from Dr. Yulong Li53). For chemogenetic experiments in VTA without projection
specificity
, DATiCre
mice
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pAAV-hsyn-GRAB_DA2m (AAV9) from Addgene Inc.
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