Fig 1: KIF11 knockdown inhibits proliferation, migration and invasion of MH7A cells.(A) The expression of KIF11 was detected by western blotting. (C)Cell viability was measured by MTT assay at 24, 48, and 72 h post-infection with control shRNA (shCtrl) or KIF11 shRNA (shKIF11) lentivirus. n = 3. ***P < 0.001 vs. Ctrl. shRNA group. (D) Edu incorporation assay. Fluorescence imaging results at 24 and 48 hours. E. The proportion of positively stained cells is displayed in a bar graph, ***P < 0.001. F. Colony formation assay. Representative images (E) and quantification (F) of colony formation assay in Ctrl. shRNA- and KIF11 shRNA infected MH7A cells after two-week culture. ***P < 0.001 vs. Ctrl.shRNA group, ###p < 0.001 vs.untreated cells.