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Nucleic Acid Purification
Nucleic Acid Purification Accessory Reagents
RNase Inhibitors
RNasin Plus RNase Inhibitor
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RNasin Plus RNase Inhibitor
RNasin Plus RNase Inhibitor
RNasin Plus RNase Inhibitor from Promega
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Citations:
(256)
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RNasin Plus RNase Inhibitor
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Description
Ribonuclease inhibitors with broad-spectrum RNase inhibitory properties. Recombinant and native available. Plus version protects RNA before, during and after heating
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
RNasin Plus RNase Inhibitor
Company
Promega
Price
Get Pricing
Get Quote for this Product
Catalog Number
N2611
Quantity
2,500u
Concentration
40 U/µL
Source
Recombinant
E. Coli
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Promega
2800 Woods Hollow Rd
Madison
,
WI
53711
United States
Phone
: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516
Email: custserv@promega.com
techserv@promega.com
Company Profile
Website:
http://www.promega.com
Citations (256)
(1)
M6A demethylase ALKBH5 mediated Igfbp4 mRNA m6A modification drives fibroblast activation and pathological upper airway fibrosis
Clin Transl Med
April 21, 2026
Jing Wang, Ziwei Liao, Mengrou Xu, Yangyang Zheng, Bin Hu, Qianhui Xia, Hongming Xu
glycine. Cells were subsequently lysed in RIP lysis buffer supplemented with RNase
inhibitors
(
Promega
,
N2611
) and
protease inhibitors
(Roche, 12352204). The lysates were then sonicated (25 amplitude with 15 cycles
(2)
Integrated multi-omics identifies macrophage ARG1-mediated deacetylation with causal and diagnostic implications in ischemic stroke
iScience
April 17, 2026
Hang-Ze Ruan, Ying Zhu, Shen-Chi Cheng, Jin-Yu Huang, Wei Hu
peptides, and recombinant proteins" ,, RNasin® Plus
Ribonuclease Inhibitor
,
Promega
,Catalog Number:
N2611
,, Critical commercial
assays
,Critical commercial
assays
,Critical commercial
assays
,, Triquick
(3)
B-type lamins maintain transcriptional homeostasis by spatially controlling chromatin-speckle proximity
Nucleic Acids Res
March 30, 2026
Geun-Seup Shin, Jinho Kim, Ji-Young Kim, Chul-Hong Kim, Mi-Jin An, Hyun-Min Lee, Ah-Ra Jo, Yuna Park, Yujeong Hwangbo, Tae Kyung Hong,
et al.
[1.5 mg/ml BSA, 5% dextran sulfate, 35% deionized formamide, 2 μg/μl tRNA, and 1 U/μl RNasin® Plus (
N2611
,
Promega
) in 4× SSC]. After rinsing with 4× SSC containing 0.1% saponin, cells were hybridized for 36
(4)
Multi-omic profiling of human and mouse dorsal root ganglia enables targeted gene delivery to nociceptors
bioRxiv
March 14, 2026
Lily S. He, Parth Bhatia, Shamsuddin A. Bhuiyan, Evangelia Semizoglou, Jiaxiang Wang, Jia Li, Joohyun Nam, Jay X. J. Luo, Chayse Arnhold, Difei Zhu,
et al.
buffer (10x Genomics) were prepared fresh, supplemented with RNase inhibitor (RNasin Plus,
Promega
N2611
), and maintained on ice. Dounce homogenizers and Tissue Tearor probes were thoroughly cleaned between
(5)
Control of retrotransposon-driven activation of the interferon response by the double-stranded RNA binding protein DGCR8
Nucleic Acids Res
March 5, 2026
Ana Gázquez-Gutiérrez, Priscilla Chin, Guillermo Peris, Katrina Gordon, Pilar G Marchante, Jeroen Witteveldt, Pablo Tristán-Ramos, Jerome O Rouvière, Lisanne I Knol, Alasdair Ivens,
et al.
resuspension buffer (20 mM Tris pH 7.5, 150 mM NaCl, 1 mM EDTA, 1 mM EGTA) containing 1 U/µL RNAsin Plus (
N2611
,
Promega
) and lysed adding 800 µl of cold lysis buffer (1% Triton X-100, 20 mM Tris pH 7.5, 150 mM NaCl,
(6)
Vitamin B2 and B3 nutrigenomics reveals a therapy for NAXD disease
Cell
February 25, 2026
Ankur Garg, Skyler Y. Blume, Helen Huynh, Alec M. Barrios, Onurkan O. Karabulut, Qian Zhao, Ayush D. Midha, Adam W. Turner, B. Vittorio Resnick, Xuewen Chen,
et al.
spermidine, 0.15 mM spermine, 1% Triton X-100) containing 1 mM RNase inhibitor (RNasin Plus,
Promega
, cat.no.
N2611
/
N2615
). Hemibrain samples were Dounce homogenized on ice using 10
strokes
of glass Pestle A and 20
strokes
(7)
Stress resilience is associated with transcriptional remodeling in the VTA
Cell Reports
February 24, 2026
Adelaide R. Minerva, Brenna McMannon, Rixing Lin, Anna Zhukovskaya, Ilana B. Witten, Catherine Jensen Peña
CA-630,
Sigma
,
I8896
Optiprep Density Gradient Medium,Sigma,D1556
RNasin Plus RNase Inhibitor
,
Promega
,
N2611
"cOmpleteTM, EDTA-free Protease Inhibitor Cocktail","Sigma, Roche",11873580001 Tricine,Sigma,T0377 Deposited
(8)
N6-methyladenosine (m6A) modification of TXNIP in 3′UTR instigates abdominal aorta aneurysm in mice
iScience
February 20, 2026
Fransky Hantelys, Wenfeng Yin, Ming Hui Zou
h. Beads were washed five times with RIP buffer, ensuring the presence of RNase inhibitor (
Promega
,
N2611
) throughout the process. Elution of mRNA fragments was achieved using 100 μL of 0.3 μg/μL Proteinase
(9)
Wdr4 regulates ribosome biogenesis and intestinal homeostasis via let-7
EMBO Reports
February 9, 2026
Kreeti Kajal, Elham Rastegari, Wen-Der Wang, Jian-Chiuan Li, Chun-Hong Chen, Wan Hsuan Chou, Wei Chiao Chang, Tzu-Yang Lin, Kevin Tsai, Tsai Ming Lu,
et al.
was subjected to decapping by using
yDcpS
(
NEB
,
M0463S
), 10× reaction buffer, RNAsin Plus (
Promega
,
N2611
), and nuclease-free water for 1 h at 37 °C, followed by
purification
using the RNA Clean and Concentrator-5
(10)
The RNA exosome maintains cellular RNA homeostasis by controlling transcript abundance in the brain
Cell Reports
January 27, 2026
Lauryn A. Higginson, Xingjun Wang, Kevin He, Maggie Torstrick, Minhoo Kim, H.R. Sagara Wijeratne, Avery M. Runnebohm, Bérénice A. Benayoun, Adam MacLean, Guillaume F. Chanfreau,
et al.
AM9530G
Triton™ X-100
,
Millipore Sigma
,Cat# T9284-100ML RNasin® Plus
Ribonuclease Inhibitor
,
Promega
,Cat#
N2611
"
Protease Inhibitor Cocktail, 50X
",
Promega
,Cat#
G6521
DL-Dithiothreitol solution
,
Millipore Sigma
,Cat#
(11)
CD13 is a bona-fide marker of bovine pre-adipocytes with potential in cultivated fat applications
npj Science of Food
January 13, 2026
Seungmee Lee, Thomas Thrower, Susanna E. Riley, Cristina L. Esteves, F. Xavier Donadeu
°C. Then, 1 µl DTT (0.1 M, Invitrogen, 18080-93), 1 µl
RNasin Plus RNase inhibitor
(40 U/µL,
Promega
,
N2611
), 1 µl
SuperScript III reverse transcriptase
(
Invitrogen
, 18080-93), and 4 µl first strand buffer (5X,
(12)
A droplet microfluidics-based platform for generating target-specific, natively-paired immune libraries and identifying potent and developable antibodies
Scientific Reports
January 3, 2026
Anusuya Ramasubramanian, Brendan T. Deveney, Sarah A. Clark, Paula Boutin, Kayla Keepseagle, Saleh Riahi, Taotao Lao, Megan Salemi, Sagar Kathuria, Pep Amengual-Rigo,
et al.
preparation details) supplemented with 2% (v/v)
RNasin® Plus RNAse inhibitor
(
Promega
, WI, Cat. No.
N2611
), was flowed at 350 µL/hr. To prepare the capture gel syringe, the desired number of gels, roughly 10
(13)
Simplified MS2 phage-like particle production including a novel maturation protein internal fusion affinity tag
Biotechnology & Biotechnological Equipment
December 31, 2025
Enos C. Kline, Rose Duong, Qin Wang, Barry R. Lutz
buffer (IDT, 11–05-01–09), and 1 μL (40 u) of RNasin® Plus
Ribonuclease Inhibitor
(
Promega Corporation
,
N2611
), with a final volume of 40 μL. Samples were heated to 65 °C for 5 min to lyse [15,16], then stored
(14)
Dysregulated Microglial Synaptic Engulfment in Diffuse Midline Glioma
BIORXIV
December 25, 2025
Rebecca Mancusi, Eva Tatlock, Kiarash Shamardani, Lehi Acosta-Alvarez, Richard Drexler, Vrunda Trivedi, Avishai Gavish, Kouta Niizuma, Neeraj Soni, Pamelyn Woo,
et al.
8.0,
Invitrogen
,
AM9856
Sucrose
,
Sigma-Aldrich
,S0389-5KG KCl,
Invitrogen
,
AM9640G
MgCl2,
Invitrogen
,
AM9530G
RNasin Plus,
Promega
,
N2611
"
Protease Inhibitor Cocktail, 50X
",
Promega
,G652A DTT,New England Biolabs,7016L Actinomycin D,Millipore
(15)
A trypanosome-specific complex mediates late-stage processing of cytosolic LSU rRNA
Nucleic Acids Res
December 11, 2025
Simona Amodeo, Mauro Fischli, Silke Oeljeklaus, Salvatore Calderaro, Bettina Warscheid, André Schneider
mM dithiothreitol (DTT)) supplemented with 2.5 µl of
RNasin Plus RNase Inhibitor
40 U/µl (
Promega
, #
N2611
) and cycloheximide (100 µg/ml). Cell extract preparation for
polysome
profiling and
polysome
profiling
(16)
Brain-immune interactions generate pathogen-specific sickness states
bioRxiv
December 8, 2025
Zuri A. Sullivan, Bertrand J. Wong, Vikrant Kapoor, Paula Kathleen Vincze, Harris S. Kaplan, Pia Giraudet, Brianna R. Watson, Adel Misherghi, Sebastian Lourido, Jeffrey R. Moffitt,
et al.
stain probe library (5 nM/oligo), 1 μM poly(A)-acrydite anchor probe, and 1% RNasin Plus (
Promega
#
N2611
) in 2× SSC). Pre-made
hybridization
mixes were stored at −20°C for several months with no observable
(17)
Long-read transcriptomics of a diverse human cohort reveals ancestry bias in gene annotation
Nat Commun
December 3, 2025
Pau Clavell-Revelles, Fairlie Reese, Sílvia Carbonell-Sala, Fabien Degalez, Carme Arnan, Winona Oliveros, Emilio Palumbo, Tamara Perteghella, Roderic Guigó, Marta Melé
M2080S
,
New England BioLabs
) with 3.5 µl of RNAse
inhibitors
(
RNasin Plus RNase Inhibitor
, catalog num.
N2611
,
Promega
) during an
incubation
time of 2 h. The final capping reaction was purified by using 1.8x AMPure
(18)
SARS-CoV-2 and HCoV-OC43 regulate host m6A modification via activation of the mTORC1 signalling pathway to facilitate viral replication
Emerging microbes & infections
December 1, 2025
Zhou S, Hui X, Wang W, Zhao C, Jin M, Qin Y, Chen M.
C0891),
Pierce Protein A/G Magnetic Beads
(
Thermo Fisher
,
88802
),
RNasin Plus RNase inhibitor
(
Promega
,
N2611
), Proteinase K (
Thermo Fisher
,
25530049
). The primary antibodies: anti METTL3 (Proteintech, 15073-I-AP),
(19)
DNA-damage dependent isoform switching modulates RIF1 DNA repair complex assembly and phase separation
Journal of Biological Chemistry
December 1, 2025
Adenine Si-Hui Koo, Weiyan Jia, Sang Hwa Kim, Mark Scalf, Claire E. Boos, Yuhong Chen, Demin Wang, Andrew F. Voter, Aditya Bajaj, Lloyd M. Smith,
et al.
mM NaCl, 0.05% v/v NP40] supplemented with 2 mM 1,4-dithiothreitol, 0.2 U/μl RNasin Plus (
Promega
,
N2611
), 20 mM sodium fluoride, 20 mM β-glycerophosphate, and 2X protease
inhibitor
cocktail (Sigma, P8340-5ml;
(20)
Repeated fentanyl abstinence intensifies opioid withdrawal and induces a proinflammatory state in striatal microglia
bioRxiv
November 11, 2025
David J. Bergkamp, Kevin R. Coffey, Aliyah J. Dawkins, Madelyn T. Rice, Ari M. Peden-Asarch, John F. Neumaier
x protein
inhibitor
cocktail [Millipore Sigma, catalog #P8340], 200 U/mL RNasin [
Promega
, catalog #
N2611
], 100 ug/mL cycloheximide [Millipore Sigma, catalog # C1988] and 1 mg/mL heparin, McKesson product #
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RNasin Plus RNase Inhibitor from Promega
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Product Specs
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