HPV16 E6 siRNA (hpv) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemHPV16 E6 siRNA (hpv)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-156008
Quantity10 µM
Specieshuman
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Small extracellular vesicle-mediated transfer of HPV16 transcripts from Ca Ski cells increases proliferation of HPV-negative recipient cancer cellsCell Communication and SignalingJune 16, 2026Sergen Arslan, Alexandre Barbaud, Jason Bernauer, Laure Avoscan, Marion Tissot, Jean-Luc Prétet, Jessica Gobbo, Carmen Garrido, Isabelle Lascombe, Sylvie Fauconnetcell transfection Control siRNA (negative control for evaluating RNAi off-target effects, sc-37007), HPV16 e6 (sc-156008), and HPV16 e7 (sc-270423) specific siRNA were from Santa Cruz Biotechnology. Ca Ski cells were seeded

(2) cIAP-2 protein is upregulated by human papillomavirus in oropharyngeal cancers: role in radioresistance in vitroInfectious Agents and CancerSeptember 27, 2024Carolina Oliva, Diego Carrillo-Beltrán, Julio C. Osorio, Iván Gallegos, Felipe Carvajal, Claudio Mancilla-Miranda, Paul Boettiger, Enrique Boccardo, Francisco AguayoHPV16 E6, HPV16 E7 and cIAP2 was performed in SCC-143 E6/E7 cells using small interfering RNA (siRNA) (SC-156008 for E6, SC-270423 for E7, SC-29850, Santa Cruz). A scramble sequence was used as the negative control

(3) HPV16E1 downregulation altered the cell characteristics involved in cervical cancer developmentScientific ReportsOctober 25, 2023Thanayod Sasivimolrattana, Arkom Chaiwongkot, Parvapan Bhattarakosol(NTC). To silence the expression of HPV16E6 and E7, SiHa cells were transfected with either HPV16E6 siRNA (sc-156008; Santa Cruz Biotechnology, USA), HPV16E7 siRNA (sc-270423; Santa Cruz Biotechnology, USA), HPV16E6 +

(4) Exploitation of ATP-sensitive potassium ion (K(ATP)) channels by HPV promotes cervical cancer cell proliferation by contributing to MAPK/AP-1 signallingOncogeneAugust 1, 2023Scarth JA, Wasson CW, Patterson MR, Evans D, Barba-Moreno D, Carden H, Cassidy R, Whitehouse A, Mankouri J, Samson A, et al.GeneSolution GS10060), and KCNJ11 (FlexiTube GeneSolution GS3767) were purchased from Qiagen. HPV16 E6 siRNA (sc-156008) and HPV16 E7 siRNA (sc-270423) were purchased from Santa Cruz Biotechnology (SCBT). HPV18 E6 siRNAs

(5) HIV-1 Proteins gp120 and Tat Promote Epithelial-Mesenchymal Transition and Invasiveness of HPV-Positive and HPV-Negative Neoplastic Genital and Oral Epithelial CellsMicrobiology spectrumDecember 21, 2022Lien K, Mayer W, Herrera R, Padilla NT, Cai X, Lin V, Pholcharoenchit R, Palefsky J, Tugizov SM.digital microscopy (Leica). Transfection of AKC-2 cells with siRNAs. The siRNAs targeting HPV-16 E6 (sc-156008) and HPV-16 E7 (sc-270423) were purchased from Santa Cruz Biotechnology; nonspecific siRNA-A (sc-37007)

(6) Fused toes homolog, a potential molecular regulator of human papillomavirus type 16 E6 and E7 oncoproteins in cervical cancerPloS oneJanuary 1, 2022D S P, Chaturvedi PK, Krishnamoorthy D, Seo YS, Thippana M, Park WY.respective viral mRNAs and the control groups were treated with scrambled siRNA (HPV16 E6: cat. no. sc-156008; HPV16 E7: cat. no. sc-270423; control siRNA cat. no. sc-37007; Santa Cruz). Briefly, cells were grown

(7) HPV-induced Nurr1 promotes cancer aggressiveness, self-renewal, and radioresistance via ERK and AKT signaling in cervical cancerCancer lettersJanuary 28, 2021Wan PK, Leung TH, Siu MK, Mo XT, Tang HW, Chan KK, Cheung AN, Ngan HY.

(8) HPV16 E6 Promotes the Progression of HPV Infection-Associated Cervical Cancer by Upregulating Glucose-6-Phosphate Dehydrogenase ExpressionFrontiers in oncologyJanuary 1, 2021Chang YF, Yan GJ, Liu GC, Hong Y, Chen HL, Jiang S, Zhong Y, Xiyang YB, Hu T.scrambled-control). Specific small interfering RNA (siRNA) aimed at human HPV E6 (siRNA E6; Santa Cruz Biotechnology; SCBT; sc-156008) and G6PD (G6PD siRNA; Santa Cruz Biotechnology; sc-60667), as well as the scrambled sequence control

(9) Autocrine STAT3 activation in HPV positive cervical cancer through a virus-driven Rac1-NFκB-IL-6 signalling axisPLoS pathogensJune 1, 2019Morgan EL, Macdonald A.HPV16, a single siRNA targeting the HPV16 E6 protein was purchased from Santa Cruz Biotechnology (SCBT; sc-156008). For each experiment, 40 nM of pooled siRNA was used and cell lysates were harvested after 72 hours. Transfections

(10) Hyaluronan-CD44 interaction promotes HPV 16 E6 oncogene-mediated oropharyngeal cell carcinoma survival and chemoresistanceMatrix biology : journal of the International Society for Matrix BiologyMay 1, 2019Bourguignon LYW, Earle C, Shiina M.

(11) HPV 16 E6/E7 up-regulate the expression of both HIF-1α and GLUT1 by inhibition of RRAD and activation of NF-κB in lung cancer cellsJournal of CancerJanuary 1, 2019Gu NJ, Wu MZ, He L, Wang XB, Wang S, Qiu XS, Wang EH, Wu GP.Institute of Biochemistry and Molecular Biology, Guangdong Medical College, China. HPV16 E6 SiRNA (sc-156008), p65 SiRNA(sc-29410) and control disordered SiRNA (sc-37007) were purchased from Santa Cruz Biotechnology

(12) Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck CancerCancer researchMay 1, 2018Brand TM, Hartmann S, Bhola NE, Li H, Zeng Y, O'Keefe RA, Ranall MV, Bandyopadhyay S, Soucheray M, Krogan NJ, et al.silencing, cells were transiently transfected with siRNAs targeting E6 and E7 (Santa Cruz Biotechnology, sc-156008 and sc-270423), HER3 siRNA (ON-TARGETplus, SMARTpool #L-003127; GE Dharmacon) or nontargeting siRNA

(13) E5 can be expressed in anal cancer and leads to epidermal growth factor receptor-induced invasion in a human papillomavirus 16-transformed anal epithelial cell lineThe Journal of general virologyMay 1, 2018Wechsler EI, Tugizov S, Herrera R, Da Costa M, Palefsky JM.

(14) Human papillomavirus E7 induces p63 expression to modulate DNA damage responseCell death & diseaseJanuary 26, 2018Eldakhakhny S, Zhou Q, Crosbie EJ, Sayan BS.of #4798, #217143, #115454) (Paisley, UK), targeting HPV-16 E6 and HPV-16 E7 were from Santa Cruz (sc-156008 and sc-270423) (Santa Cruz Inc.). Scrambled control siRNA was from Qiagen (#1027310) (QIAGEN Ltd., Manchester,

(15) HPV16 E6/E7 upregulates HIF-2α and VEGF by inhibiting LKB1 in lung cancer cellsTumour biology : the journal of the International Society for Oncodevelopmental Biology and MedicineJuly 1, 2017Shao JS, Sun J, Wang S, Chung K, Du JT, Wang J, Qiu XS, Wang EH, Wu GP.reverse transcriptase-polymerase chain reaction (qRT-PCR). Small-interfering RNA HPV16 E6 small-interfering RNA (SiRNA; sc-156008), HPV16 E7 SiRNA (sc-270423), LKB1 SiRNA (sc-35816), and Control SiRNA (sc-37007) were purchased from

(16) Human Papillomavirus Regulates HER3 Expression in Head and Neck Cancer: Implications for Targeted HER3 Therapy in HPV(+) PatientsClinical cancer research : an official journal of the American Association for Cancer ResearchJune 15, 2017Brand TM, Hartmann S, Bhola NE, Peyser ND, Li H, Zeng Y, Isaacson Wechsler E, Ranall MV, Bandyopadhyay S, Duvvuri U, et al.Pool, #D-001810; Dharmacon). siRNAs targeting E6 and E7 were purchased from Santa Cruz Biotechnology, sc-156008 and sc-270423. Lipofectamine RNAiMAX was used for all siRNA experiments according to the manufacturer’s

(17) Human papillomavirus oncoprotein E6 upregulates c-Met through p53 downregulationEur J CancerSeptember 1, 2016Qian G, Wang D, Magliocca KR, Hu Z, Nannapaneni S, Kim S, Chen Z, Sun SY, Shin DM, Saba NF, et al.

(18) MiR-375 Is Epigenetically Downregulated by HPV-16 E6 Mediated DNMT1 Upregulation and Modulates EMT of Cervical Cancer Cells by Suppressing lncRNA MALAT1PloS oneJanuary 1, 2016Liu S, Song L, Yao H, Zhang L, Xu D, Gao F, Li Q.37°C. Cell transfection and treatment SiHa and CaSki cells were transfected with 100 nM HPV-16 E6 siRNA (sc-156008, Santa Cruz Biotechnology, Santa Cruz, CA, USA), 100 nM DNMT1 siRNA (Ribobio, Guangzhou, China) or 100

(19) Human papillomavirus 16 oncoprotein regulates the translocation of β-catenin via the activation of epidermal growth factor receptorCancerJanuary 15, 2015Hu Z, Müller S, Qian G, Xu J, Kim S, Chen Z, Jiang N, Wang D, Zhang H, Saba NF, et al.

(20) Deregulation of microRNAs Let-7a and miR-21 mediate aberrant STAT3 signaling during human papillomavirus-induced cervical carcinogenesis: role of E6 oncoproteinBMC cancerDecember 23, 2014Shishodia G, Verma G, Srivastava Y, Mehrotra R, Das BC, Bharti AC.

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