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Inhibitors
Lactacystin
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Lactacystin Chemicals
Lactacystin from Santa Cruz Biotechnology, Inc.
Be the first to write a review!
Citations:
(62)
Supplier Page
Supplier Page from
Santa Cruz Biotechnology, Inc. for
Lactacystin
Description
Cell-permeable, irreversible inhibitor of the 20S proteasome. Blocks proteasome activity by targeting the catalytic beta subunit of the proteasome by covalently attaching to the N-terminal Thr of subunit X. Induces apoptosis in U-937.
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Lactacystin
Company
Santa Cruz Biotechnology, Inc.
Price
$165.00
Supplier Page
View Company Product Page
Catalog Number
sc-3575
Quantity
200 µg
Type
Biochemical Reagents
Molecular Weight
376.43
Add to Compare List
Santa Cruz Biotechnology, Inc.
10410 Finnell Street
Dallas
,
Texas
75220
United States
Phone
: 1-800-457-3801
831-457-3801
Company Profile
Website:
http://www.scbt.com/
Citations (62)
(1)
Attenuation of IFITM proteins’ antiviral activity through sequestration into intraluminal vesicles of late endosomes
Frontiers in Immunology
August 21, 2025
David Prikryl, You Zhang, Smita Verma, Gregory B. Melikyan
Louis, MO, USA). MG-132 (Cat.
474791
) was purchased from Calbiochem (Columbus, OH, USA).
Lactacystin
(
sc-3575
) was purchased from
Santa Cruz
Biotech (Dallas, TX, USA). Recombinant human EGF (Cat. 236-EG) was purchased
(2)
Attenuation of IFITM proteins’ antiviral activity through sequestration into intraluminal vesicles of late endosomes
bioRxiv
May 29, 2025
David Prikryl, You Zhang, Gregory B. Melikyan
Louis, MO, USA).
MG-132
(Cat.
474791
) was purchased from Calbiochem (Columbus, OH, USA).
Lactacystin
(
sc-3575
) was purchased from
Santa Cruz
Biotech (Dallas, TX, USA). Recombinant human EGF (Cat. 236-EG) was purchased
(3)
Palmitoyltransferase DHHC9 and acyl protein thioesterase APT1 modulate renal fibrosis through regulating β-catenin palmitoylation
Nature communications
October 21, 2023
Gu M, Jiang H, Tan M, Yu L, Xu N, Li Y, Wu H, Hou Q, Dai C.
(cat:
240-B-010-CF
,
R&D Systems
, Minneapolis, MN), MG132 (cat: M8699,
Sigma-Aldrich
),
Lactacystin
(cat:
sc3575
,
Santa Cruz
), ICG001 (cat:
A8217
, Apexbio, USA), Recombinant Human
DHHC9
protein (cat: ab162420, abcam),
(4)
Lignin-carbohydrate complexes suppress SCA3 neurodegeneration via upregulating proteasomal activities
International journal of biological macromolecules
October 1, 2022
Chen ZS, Yan M, Pei W, Yan B, Huang C, Chan HYE.
(5)
Severe Gestational Low-Protein Intake Impacts Hippocampal Cellularity, Tau, and Amyloid-β Levels, and Memory Performance in Male Adult Offspring: An Alzheimer-Simile Disease Model?
Journal of Alzheimer's disease reports
January 1, 2022
Grigoletti-Lima GB, Lopes MG, Franco ATB, Damico AM, Boer PA, Rocha Gontijo JA.
Biotech, Inc., dilution,
1:1000
), Aβ (
sc 374527
;
Santa Cruz
Biotech, Inc., dilution,
1:1000
),
HSP70
(
sc3575
;
Santa Cruz
Biotech, Inc., dilution,
1:1000
), and HSP90 (
sc7947
;
Santa Cruz
Biotech, Inc., dilution,
(6)
Herpesvirus-mediated stabilization of ICP0 expression neutralizes restriction by TRIM23
Proceedings of the National Academy of Sciences of the United States of America
December 21, 2021
Liu X, Acharya D, Krawczyk E, Kangas C, Gack MU, He B.
(7)
The von Hippel-Lindau Cullin-RING E3 ubiquitin ligase regulates APOBEC3 cytidine deaminases
Translational research : the journal of laboratory and clinical medicine
November 1, 2021
Scholtes GK, Sawyer AM, Vaca CC, Clerc I, Roh M, Song C, D'Aquila RT.
(8)
A fine balance between Prpf19 and Exoc7 in achieving degradation of aggregated protein and suppression of cell death in spinocerebellar ataxia type 3
Cell death & disease
February 2, 2021
Chen ZS, Huang X, Talbot K, Chan HYE.
(9)
Compensatory increase of VE-cadherin expression through ETS1 regulates endothelial barrier function in response to TNFα
Cellular and molecular life sciences : CMLS
June 1, 2020
Colás-Algora N, García-Weber D, Cacho-Navas C, Barroso S, Caballero A, Ribas C, Correas I, Millán J.
chloride (A9434), GI254023X (SML0789) and LPS (L8274) were purchased from
Sigma-Aldrich
.
Lactacystin
(
sc-3575
) was purchased from
Santa Cruz Biotechnology, Inc
. Recombinant human TNFα (210-TA/CF) was obtained from
(10)
Loss of Rictor in tubular cells exaggerates lipopolysaccharide induced renal inflammation and acute kidney injury via Yap/Taz-NF-κB axis
Cell death discovery
January 1, 2020
Gui Y, Hou Q, Lu Q, Dai C, Li J.
(11)
African Swine Fever Virus Ubiquitin-Conjugating Enzyme Interacts With Host Translation Machinery to Regulate the Host Protein Synthesis
Frontiers in microbiology
January 1, 2020
Barrado-Gil L, Del Puerto A, Muñoz-Moreno R, Galindo I, Cuesta-Geijo MÁ, Urquiza J, Nistal-Villán E, Maluquer de Motes C, Alonso C.
(12)
Cell assay for the identification of amyloid inhibitors in systemic AA amyloidosis
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis
March 1, 2019
Puscalau-Girtu I, Scheller JS, Claus S, Fändrich M.
(13)
The feline calicivirus leader of the capsid protein causes survivin and XIAP downregulation and apoptosis
Virology
January 15, 2019
Barrera-Vázquez OS, Cancio-Lonches C, Hernández-González O, Chávez-Munguia B, Villegas-Sepúlveda N, Gutiérrez-Escolano AL.
(14)
Hsp70 Interacts with Mitogen-Activated Protein Kinase (MAPK)-Activated Protein Kinase 2 To Regulate p38MAPK Stability and Myoblast Differentiation during Skeletal Muscle Regeneration
Molecular and cellular biology
December 15, 2018
Fan W, Gao XK, Rao XS, Shi YP, Liu XC, Wang FY, Liu YF, Cong XX, He MY, Xu SB,
et al
.
(Ser78) (
Millipore
;
04-447
). Chemical reagents used included the following: lactacystin (
Santa Cruz
;
sc-3575
), MG132 (
Santa Cruz
;
sc-201270
), VER155008 (
Santa Cruz
;
sc-358808
), SB203580 (
Cayman
;
13067
), cycloheximide
(15)
Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions
Nature communications
October 12, 2018
Fornasiero EF, Mandad S, Wildhagen H, Alevra M, Rammner B, Keihani S, Opazo F, Urban I, Ischebeck T, Sakib MS,
et al
.
(16)
The HCM-linked W792R mutation in cardiac myosin-binding protein C reduces C6 FnIII domain stability
American journal of physiology. Heart and circulatory physiology
June 1, 2018
Smelter DF, de Lange WJ, Cai W, Ge Y, Ralphe JC.
bacterial
protein extraction
reagent (B-PER, catalog no.
89822
,
Thermo Fisher
), lactacystin (catalog no.
SC-3575
,
Santa Cruz Biotechnology
), and SYPRO
orange
(catalog no.
S6650
,
ThermoFisher
).
Sequence analysis
. All
(17)
Carcinoma associated fibroblasts (CAFs) promote breast cancer motility by suppressing mammalian Diaphanous-related formin-2 (mDia2)
PloS one
January 1, 2018
Dvorak KM, Pettee KM, Rubinic-Minotti K, Su R, Nestor-Kalinoski A, Eisenmann KM.
(18)
Icariin promotes the migration of bone marrow stromal cells via the SDF-1α/HIF-1α/CXCR4 pathway
Drug design, development and therapy
January 1, 2018
Zhu H, Wang X, Han Y, Zhang W, Xin W, Zheng X, Zhang J.
(19)
Innate Sensing of Influenza A Virus Hemagglutinin Glycoproteins by the Host Endoplasmic Reticulum (ER) Stress Pathway Triggers a Potent Antiviral Response via ER-Associated Protein Degradation
Journal of virology
January 1, 2018
Frabutt DA, Wang B, Riaz S, Schwartz RC, Zheng YH.
(20)
Glutamine promotes Hsp70 and inhibits α-Synuclein accumulation in pheochromocytoma PC12 cells
Experimental and therapeutic medicine
August 1, 2017
Wang H, Tang C, Jiang Z, Zhou X, Chen J, Na M, Shen H, Lin Z.
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Reviews
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Lactacystin from Santa Cruz Biotechnology, Inc.
Supplier Page
View Company Product Page
$165.00
Product Specs
Company Info
Citations
Reviews
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