(Z)-4-Hydroxytamoxifen from Santa Cruz Biotechnology, Inc.

Product Specs
Item(Z)-4-Hydroxytamoxifen
CompanySanta Cruz Biotechnology, Inc.
Price $275.00Supplier Page View Company Product Page
Catalog Numbersc-3542
Quantity5 mg
TypeBiochemical Reagents
Molecular Weight387.51

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Pharmacological inhibition of NT5C2 reverses genetic and non-genetic drivers of 6-MP resistance in acute lymphoblastic leukemiaCancer DiscovNovember 2, 2022Clara Reglero, Chelsea L. Dieck, Arie Zask, Farhad Forouhar, Anouchka P. Laurent, Wen-Hsuan W. Lin, Robert Albero, Hannah I. Miller, Cindy Ma, Julie M Gastier-Foster, et al.with doxycycline (1 mg ml−1). We purchase 4-hydroxytamoxifen from Sigma-Santa Cruz Biotechnology (#SC-3542) and we dissolve it in 100% ethanol for in vitro assays. We purchased 6-mercaptopurine monohydrate (6-MP,

(2) Pharmacological inhibition of NT5C2 reverses genetic and non-genetic drivers of 6-MP resistance in acute lymphoblastic leukemiaCancer DiscoveryNovember 2, 2022Clara Reglero, Chelsea L. Dieck, Arie Zask, Farhad Forouhar, Anouchka P. Laurent, Wen-Hsuan W. Lin, Robert Albero, Hannah I. Miller, Cindy Ma, Julie M. Gastier-Foster, et al.with doxycycline (1 mg ml−1). We purchase 4-hydroxytamoxifen from Sigma-Santa Cruz Biotechnology (#SC-3542) and we dissolve it in 100% ethanol for in vitro assays. We purchased 6-mercaptopurine monohydrate (6-MP,

(3) A gene dosage-dependent effect unveils NBS1 as both a haploinsufficient tumour suppressor and an essential gene for SHH-medulloblastomaNeuropathology and applied neurobiologyOctober 1, 2022Petroni M, Fabretti F, Di Giulio S, Nicolis di Robilant V, La Monica V, Moretti M, Belardinilli F, Bufalieri F, Coppa A, Paci P, et al.Information). After three days, subconfluent adhering cells were treated with 1 μM 4‐hydroxytamoxifen (SC‐3542, Santa Cruz Biotechnology) or ethanol for 24 h and analysed 48 h after tamoxifen wash out. For Nbn RNA interference

(4) Oncogenic Vav1-Myo1f induces therapeutically targetable macrophage-rich tumor microenvironment in peripheral T cell lymphomaCell reportsApril 19, 2022Cortes JR, Filip I, Albero R, Patiño-Galindo JA, Quinn SA, Lin WW, Laurent AP, Shih BB, Brown JA, Cooke AJ, et al.different treatment groups. METHOD DETAILS Drugs (Z)-4-hydroxytamoxifen (Santa Cruz Biotechnology, SC-3542) was dissolved in ethanol and added to the cell culture media at a final concentration of 1 μmol/L.

(5) Screening for androgen agonists using autonomously bioluminescent HEK293 reporter cellsBioTechniquesAugust 1, 2021Xu T, Gilliam M, Sayler G, Ripp S, Close D.

(6) Analysis of tamoxifen and its metabolites in dried blood spot and volumetric absorptive microsampling: comparison and clinical applicationHeliyonJune 1, 2021Maggadani BP, Harahap Y, Harmita, Haryono SJ, Untu CWP.

(7) Volumetric Absorptive Microsampling as a New Biosampling Tool for Monitoring of Tamoxifen, Endoxifen, 4-OH Tamoxifen and N-Desmethyltamoxifen in Breast Cancer PatientsDrug design, development and therapyJanuary 1, 2021Maggadani BP, Harmita, Haryono SJ, Rinaldi MR, Harahap Y.

(8) Primary cilia control glucose homeostasis via islet paracrine interactionsProceedings of the National Academy of Sciences of the United States of AmericaApril 21, 2020Hughes JW, Cho JH, Conway HE, DiGruccio MR, Ng XW, Roseman HF, Abreu D, Urano F, Piston DW.induction was performed in isolated βCKO-ERT2 islets using 2.5 μmol/L of 4-hydroxy tamoxifen (Santa Cruz sc-3542) in the culture media and replenished with media change every 2 d. Loss of cilia was confirmed by immunostaining

(9) GATA3-Controlled Nucleosome Eviction Drives MYC Enhancer Activity in T-cell Development and LeukemiaCancer discoveryDecember 1, 2019Belver L, Yang AY, Albero R, Herranz D, Brundu FG, Quinn SA, Pérez-Durán P, Álvarez S, Gianni F, Rashkovan M, et al.neighboring region (5’-TCACCCCAAGCCCAGTGCCTGTCATATGGGA-3’). Drugs (Z)-4-hydroxytamoxifen (Santa Cruz SC-3542) was dissolved in ethanol and added to the media at a final concentration of 1μM. Tamoxifen (Sigma T5648)

(10) Blocking TNFα-driven astrocyte purinergic signaling restores normal synaptic activity during epileptogenesisGliaDecember 1, 2018Nikolic L, Shen W, Nobili P, Virenque A, Ulmann L, Audinat E.

(11) RHOA G17V Induces T Follicular Helper Cell Specification and Promotes LymphomagenesisCancer cellFebruary 12, 2018Cortes JR, Ambesi-Impiombato A, Couronné L, Quinn SA, Kim CS, da Silva Almeida AC, West Z, Belver L, Martin MS, Scourzic L, et al.Rhoaco-G17V/+;CD4CreERT2 mice were treated with vehicle or 4-hydroxytamoxifen (Santa Cruz Biotechnology, sc-3542) for 48 hr in RPMI1640 media supplemented with 10% FBS and 20 ng mL−1 IL-7. To assess cell proliferation,

(12) Methods for High-throughput Drug Combination Screening and Synergy ScoringMethods in molecular biology (Clifton, N.J.)January 1, 2018He L, Kulesskiy E, Saarela J, Turunen L, Wennerberg K, Aittokallio T, Tang J.

(13) An autocrine purinergic signaling controls astrocyte-induced neuronal excitationScientific reportsSeptember 12, 2017Shen W, Nikolic L, Meunier C, Pfrieger F, Audinat E.

(14) Chemical and toxicological characterisation of anticancer drugs in hospital and municipal wastewaters from Slovenia and SpainEnvironmental pollution (Barking, Essex : 1987)December 1, 2016Isidori M, Lavorgna M, Russo C, Kundi M, Žegura B, Novak M, Filipič M, Mišík M, Knasmueller S, de Alda ML, et al.

(15) Ozonation of hospital raw wastewaters for cytostatic compounds removal. Kinetic modelling and economic assessment of the processThe Science of the total environmentJune 15, 2016Ferre-Aracil J, Valcárcel Y, Negreira N, de Alda ML, Barceló D, Cardona SC, Navarro-Laboulais J.

(16) Calcium dynamics in astrocyte processes during neurovascular couplingNature neuroscienceFebruary 1, 2015Otsu Y, Couchman K, Lyons DG, Collot M, Agarwal A, Mallet JM, Pfrieger FW, Bergles DE, Charpak S.expression was induced by a single intraperitoneal injection of 2 mg 4-hydroxytamoxifen (Santa Cruz, sc-3542). GLAST-CreERT+/− mice (B6.Cg-Tg(Slc1a3-cre/ERT)1Nat/J, Jackson Labs) were also crossed with the R26-lsl-GCaMP3+/+

(17) Cytostatic drugs and metabolites in municipal and hospital wastewaters in Spain: filtration, occurrence, and environmental riskThe Science of the total environmentNovember 1, 2014Negreira N, de Alda ML, Barceló D.

(18) Study of the stability of 26 cytostatic drugs and metabolites in wastewater under different conditionsThe Science of the total environmentJune 1, 2014Negreira N, López de Alda M, Barceló D.

(19) Multianalyte determination of 24 cytostatics and metabolites by liquid chromatography-electrospray-tandem mass spectrometry and study of their stability and optimum storage conditions in aqueous solutionTalantaNovember 15, 2013Negreira N, Mastroianni N, López de Alda M, Barceló D.

(20) On-line solid phase extraction-liquid chromatography-tandem mass spectrometry for the determination of 17 cytostatics and metabolites in waste, surface and ground water samplesJournal of chromatography. AMarch 8, 2013Negreira N, López de Alda M, Barceló D.