Necrostatin-1 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemNecrostatin-1
CompanySanta Cruz Biotechnology, Inc.
Price $92.00Supplier Page View Company Product Page
Catalog Numbersc-200142
Quantity20 mg
TypeBiochemical Reagents
Molecular Weight259.32

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Conjugated fatty acids drive ferroptosis through chaperone-mediated autophagic degradation of GPX4 by targeting mitochondriaCell Death & DiseaseDecember 6, 2024Yusuke Hirata, Yuto Yamada, Soma Taguchi, Ryota Kojima, Haruka Masumoto, Shinnosuke Kimura, Takuya Niijima, Takashi Toyama, Ryoji Kise, Emiko Sato, et al.(#SML2234), Ferrostatin-1 (#SML0583) (Sigma, Burlington, MA, USA), mito-TEMPO (#sc-221945), Necrostatin-1 (#sc-200142), MG132 (#sc-201270) (Santa Cruz, Dallas, TX, USA), z-VAD-fmk (#3188-v) (Peptide Institute, Osaka, Japan),

(2) Superparamagnetic Iron Oxide Nanoparticles Reprogram the Tumor Microenvironment and Reduce Lung Cancer Regrowth after Crizotinib TreatmentACS NanoApril 30, 2024Natalie K. Horvat, Sara Chocarro, Oriana Marques, Tobias A. Bauer, Ruiyue Qiu, Alberto Diaz-Jimenez, Barbara Helm, Yuanyuan Chen, Stefan Sawall, Richard Sparla, et al.Diagnostika), 0.25 mM 3-methyladenine (HY-19312-100 mg, Hoelzel Diagnostika), and 0.2 μM necrostatin-1 (sc-200142, Santa Cruz Biotechnology) were used on cocultures of BMDMs and cancer cells for the indicated times. Flow Cytometry

(3) Role of ATP5G3 in sodium nitroprusside-induced cell death in cervical carcinoma cellsJournal of biochemical and molecular toxicologyMarch 1, 2023Lee KH, Rim DE, Lee JH, Jeong SW.

(4) Direct activation of microglia by β-glucosylceramide causes phagocytosis of neurons that exacerbates Gaucher diseaseImmunityFebruary 14, 2023Shimizu T, Schutt CR, Izumi Y, Tomiyasu N, Omahdi Z, Kano K, Takamatsu H, Aoki J, Bamba T, Kumanogoh A, et al.

(5) MyD88 deficiency aggravates the severity of acute pancreatitis by promoting MyD88-independent TRIF pathway-mediated necrosisAnnals of translational medicineNovember 1, 2022Yang DJ, Wang XD, Fu XY, Lu HM, Zhou ZG, Liu Y.

(6) Podocytes are lost from glomeruli before completing apoptosisAmerican journal of physiology. Renal physiologyNovember 1, 2022Yamamoto K, Okabe M, Tanaka K, Yokoo T, Pastan I, Araoka T, Osafune K, Udagawa T, Koizumi M, Matsusaka T.

(7) The Anti-Tumor and Immunomodulatory Effects of PLGA-Based Docetaxel Nanoparticles in Lung Cancer: The Potential Involvement of Necroptotic Cell Death through Reactive Oxygen Species and Calcium Build-UpVaccinesOctober 26, 2022Gupta P, Singh A, Verma AK, Kant S, Pandey AK, Khare P, Prakash V.

(8) The Possible Connection of Two Dual Function Processes: The Relationship of Ferroptosis and the JNK PathwayInternational journal of molecular sciencesSeptember 20, 2022Varga D, Hajdinák P, Makk-Merczel K, Szarka A.solved in DMSO), 50 μM final concentration of necrostatin-1 (Santa Cruz Biotechnology, Dallas, TX, USA, sc-200142, solved in DMSO), 500 nM final concentration of liproxstatin-1 (MCE®, HY-12726, solved in DMSO), 5 μM

(9) N6-isopentenyladenosine induces cell death through necroptosis in human glioblastoma cellsCell death discoveryApril 7, 2022Pagano C, Navarra G, Coppola L, Avilia G, Pastorino O, Della Monica R, Buonaiuto M, Torelli G, Caiazzo P, Bifulco M, et al.

(10) RETRA induces necroptosis in cervical cancer cells through RIPK1, RIPK3, MLKL and increased ROS productionEuropean journal of pharmacologyApril 5, 2022Mohanty S, Yadav P, Lakshminarayanan H, Sharma P, Vivekanandhan A, Karunagaran D.

(11) Therapeutic potentials of cell death inhibitors in rats with cardiac ischaemia/reperfusion injuryJournal of cellular and molecular medicineApril 1, 2022Luo Y, Apaijai N, Liao S, Maneechote C, Chunchai T, Arunsak B, Benjanuwattra J, Yanpiset P, Chattipakorn SC, Chattipakorn N.

(12) Innate immune sensing of influenza A viral RNA through IFI16 promotes pyroptotic cell deathiScienceJanuary 21, 2022Mishra S, Raj AS, Kumar A, Rajeevan A, Kumari P, Kumar H.proteins" ,, Z-VAD(OMe)-FMK,Santa Cruz Biotechnology,sc-311561 Necrostatin-1,Santa Cruz Biotechnology,sc-200142 ,, Critical commercial assays,Critical commercial assays,Critical commercial assays ,, FAM-FLICA,Immunochemistry

(13) Ferroptosis as a Novel Determinant of β-Cell Death in Diabetic ConditionsOxidative medicine and cellular longevityJanuary 1, 2022Stancic A, Saksida T, Markelic M, Vucetic M, Grigorov I, Martinovic V, Gajic D, Ivanovic A, Velickovic K, Savic N, et al.and MitoTracker Red-FM were obtained from Thermo Fisher Scientific (CA, USA). Necrostatin-1 (Nec-1) (sc-200142) was purchased from Santa Cruz Biotechnology (TX, USA). Caspase inhibitor Z-VAD-FMK (Z-VAD) (G7231)

(14) Oncolytic reovirus-mediated killing of mouse cancer-associated fibroblastsInternational journal of pharmaceuticsDecember 15, 2021Kurisu N, Kaminade T, Eguchi M, Ishigami I, Mizuguchi H, Sakurai F.

(15) Sequential oncogenic mutations influence cell competitionCurrent biology : CBSeptember 27, 2021Kohashi K, Mori Y, Narumi R, Kozawa K, Kamasaki T, Ishikawa S, Kajita M, Kobayashi R, Tamori Y, Fujita Y.

(16) The Performance of HepG2 and HepaRG Systems through the Glass of Acetaminophen-Induced ToxicityLife (Basel, Switzerland)August 21, 2021Lőrincz T, Deák V, Makk-Merczel K, Varga D, Hajdinák P, Szarka A.

(17) The E3 Ubiquitin-Protein Ligase RNF4 Promotes TNF-α-Induced Cell Death Triggered by RIPK1International journal of molecular sciencesMay 28, 2021Shimada T, Kudoh Y, Noguchi T, Kagi T, Suzuki M, Tsuchida M, Komatsu H, Takahashi M, Hirata Y, Matsuzawa A.

(18) trans-Fatty acids promote p53-dependent apoptosis triggered by cisplatin-induced DNA interstrand crosslinks via the Nox-RIP1-ASK1-MAPK pathwayScientific reportsMay 14, 2021Hirata Y, Takahashi M, Yamada Y, Matsui R, Inoue A, Ashida R, Noguchi T, Matsuzawa A.

(19) Acute Increases in Intracellular Zinc Lead to an Increased Lysosomal and Mitochondrial Autophagy and Subsequent Cell Demise in Malignant MelanomaInternational journal of molecular sciencesJanuary 11, 2021Rudolf E, Rudolf K.

(20) Clustering of Tir during enteropathogenic E. coli infection triggers calcium influx-dependent pyroptosis in intestinal epithelial cellsPLoS biologyDecember 1, 2020Zhong Q, Roumeliotis TI, Kozik Z, Cepeda-Molero M, Fernández LÁ, Shenoy AR, Bakal C, Frankel G, Choudhary JS.