i-Series Integrated HPLC/UHPLC from Shimadzu

Product Specs
Itemi-Series Integrated HPLC/UHPLC
CompanyShimadzu
Price Get Pricing
Catalog Numberi-Series LC-2070/2080
QuantityEA
Maximum Pressure50 Mpa or 70 Mpa
TypeHPLC / UHPLC
SoftwareLabSolutions
Temperature RangeUp to 90°C
ApplicationsPharmaceutical, Food and Beverage, Chemical and Environmental analyses
Capacity6 Columns
Flow Rate0.0001 to 10 mL/min

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Shimadzu

7102 Riverwood Drive

Columbia, Maryland

United States

Phone: 1-800-477-1227
1-800-477-1227
1-410-381-1222

Company Profile

Website: https://www.ssi.shimadzu.com/

(1) High-yield production of hydroxytyrosol through metabolic engineering of Yarrowia lipolyticaSynthetic and Systems BiotechnologySeptember 1, 2026Bihuan Chen, Yuanyuan Wang, Danlin Wang, Yina Wang, Xiangyu Liu, Guanghui Zhang, Shengchao Yangby high-performance liquid chromatography (HPLC). Quantitative analysis was performed on a SHIMADZU (LC-2050C 3D) instrument equipped with a SHIMSEN SuperbII C18 column (4.6 × 250 mm, 5 μm) at 35 °C, with a 10 μL

(2) Minicells derived from Escherichia coli Nissle 1917 for efficient phenylalanine degradationApplied and Environmental MicrobiologyAugust 19, 2026Xiaoya Tian, Kanghui Ju, Jun Zeng, Xiaona Pang, Jingyu Chenfiltered (0.22 µm) for HPLC analysis. Phe, PP, TCA, and other metabolites were quantified using HPLC (LC-2050; Shimadzu, Japan), with an Agilent ZORBAX SB-C18 column (250 mm × 4.6 mm, 5 µm) and an ultraviolet (UV)

(3) 6'‑O‑Caffeoylarbutin attenuates experimental hyperuricemia by regulating renal and intestinal urate transport, intestinal barrier integrity, and gut microbiotaMol Med RepAugust 18, 2026Xuezhi Yu, Yang Zhang, Konchun Sun, Rui Yang, Xingde Li, Xiuzhen Chen, Tiantian Li, Xiaolei Yang, Ming Li, Lu Liu, et al.Briefly, the sample was dissolved in methanol, filtered through a 2.5-µm membrane and analyzed using an LC-2050C 3D HPLC (Shimadzu Corporation) system equipped with a Hypersil GOLD C18 column (Thermo Fisher Scientific,

(4) Green Tea Extract Attenuates Oxidative Stress and Prolongs Red Blood Cell Survival in Iron-Overloaded β-Thalassemic MiceAntioxidants (Basel)August 10, 2026Yanping Zhong, Sakaewan Ounjaijean, Sirichai Srichairatanakool, Narisara Paradee, Suphatta Yubo, Honghong Xu, Pimpisid Koonyosying, Phatchariya Phannasil, Saovaros Svasti, Somdet Srichairatanakoolmethods [14,21]. Briefly, 10 µL of GTE solution (1.1 mg) was injected into an HPLC system (i-Series LC-2050, Shimadzu Corporation, Kyoto, Japan) equipped with a PDA detector (SPD-M20A, Shimadzu Corporation).

(5) Latanoprost Acid-Brimonidine, a New Amide Prodrug for Glaucoma Management Based on the Concept of Sustained ReleaseMoleculesAugust 10, 2026Hong-Jia Lin, Shih-Horng Su, Wen-Chung WuLiquid Chromatograph (HPLC) and Mass Spectrometer (MS) Both spectra were measured using a SHIMADZU LC-2050C equipped with different columns. For HPLC, ODS-100V, 4.6 × 250 mm, purchased from TOSOH; mobile phase:

(6) Liquisolid Technology Improves and Reduces Source-Dependent Variability in Andrographolide Dissolution from Andrographis paniculata ExtractsPharmaceuticsAugust 8, 2026Peera Tabboon, Ekapol Limpongsa, Sarunya Tuntiyasawasdikul, Tanyarat Yodthong, Watchara Kanjanakawinkul, Napaphak Jaipakdee[43]. 2.7. HPLC Methodology for AG Measurement The AG and DDAG levels were measured using an HPLC system (LC-2050, Shimadzu, Kyoto, Japan) consisting of a photodiode array detector and a temperature control module,

(7) Xeniaphyllane-Type Diterpenoids from the Soft Coral Sclerophytum humesi: Resolving Absolute Configurations and Anti-Alzheimer's PotentialJ Nat ProdJuly 24, 2026Phuong Vu Luu, Cuong-Quoc Nguyen, Huong Lien Ton-Nu, Thuy-Tien Thi Phan, Quoc-Dung Tran Huynh, Ngoc-Thac Pham, Huong-Giang Le, Lo-Yun Chen, Yu-Chia Chang, Jui-Hsin Su, et al.high-performance liquid chromatography (HPLC). Semipreparative separations were performed on a Shimadzu LC-2050 system (Kyoto, Japan) equipped with a Galaksil EF-C18–H reverse-phase column (120 Å, 5 μm, 10 × 250

(8) DNAJC12 Stabilizes Phenylalanine Hydroxylase and Facilitates Its Substrate‐Dependent ActivationFASEB JJuly 24, 2026Mary Dayne S. Tai, Trond‐André Kråkenes, Gloria Gamiz‐Arco, Christer F. Didriksen, Juha P. Kallio, Marte I. Flydal, Fernando Moro, Aurora MartinezThe proteins were analyzed using a Superdex 200 Increase (1.0 × 30 cm) column connected to an iSeries LC‐2050 (Shimadzu) HPLC system coupled to a RefractoMax 520 module (ERC GmbH) to measure the refractive index

(9) Structure-based functionality of a multi-domain periplasmic chitodextrinase from marine bacterium Vibrio choleraeJournal of Biological ChemistryJuly 21, 2026Kanokbhorn Khumnonkhro, Thitipat Chongrungreang, Shohei Sakuda, Robert Chales Robinson, Tamo Fukamizo, Wipa Sugintaspherical silica particles, Tosoh, Tokyo, Japan) (59) connected to an HPLC system (Shimadzu i-series, LC-2050C 3D, Genzo Shimadzu). The separation of the individual products, including α- and β-anomers was conducted

(10) Analytical Validation of an HPLC-DAD Method for Ivermectin Quantification in Polymeric NanocapsulesACS OmegaJuly 14, 2026Mariana Alice Gonzaga Gabú, Mylena Lemos Dos Santos, Laryssa Ferreira do Nascimento Silva, Paloma Manuelle Marques da Silva, Danilo César Galindo Bedor, Douglas Dourado, Fábio Rocha FormigaChromatography Conditions The High-Performance Liquid Chromatography (HPLC) system consisted of a Shimadzu LC-2050C 3D model equipped with a Diode Array Detector (DAD). Chromatographic separation was performed using a Zorbax

(11) Cetyl All-Trans-Retinoate as a Lipidic ATRA Prodrug with Enhanced Anticancer and Chemosensitizing ActivityInt J Mol SciJuly 3, 2026Paweł Moroz, Klaudia Muciek, Marta Świtalska, Joanna Wietrzyk, Zbigniew Lazar, Anna Gliszczyńskathin-layer chromatography (TLC). Samples were also analyzed by high-performance liquid chromatography (HPLC) using a Shimadzu LC-2050C 3D system (Shimadzu, Kyoto, Japan) equipped with an evaporative light scattering detector (ELSD). The autosampler

(12) "Optimization of Extraction Buffer Conditions for Improved Heparin Affinity-Based Quantification of Bovine Lactoferrin in Various Dairy Products"Journal of AOAC InternationalJuly 1, 2026Tomoaki Fukushima, Keisuke Yamamoto, Yukino Sato, Tatsuya Nojima, Mirei Odaka, Norichika Nishida, Hiroshi Ochistandard extraction buffer (phosphate buffer). Experimental Apparatus HPLC.—HPLC was performed on an LC-2050C 3D system (Shimadzu, Kyoto, Japan) with a UV detector. Reversed-phase HPLC column.—A Waters XBridge Protein

(13) Sclerofish A and B: Two Pairs of Enantiomeric Diterpenoids Featuring a 4/7/6-Fused Tricyclic Scaffold from the Soft Coral Sclerophytum humesiJ Org ChemJune 19, 2026Phuong Vu Luu, Thuy-Tien Thi Phan, Quoc-Dung Tran Huynh, Ngoc-Thac Pham, Huong-Giang Le, Lo-Yun Chen, Huong Lien Ton-Nu, Cuong-Quoc Nguyen, Yao-An Shen, Yu-Jui Fan, et al.(HPLC) was employed to purify the target constituents. Semipreparative HPLC was performed on a Shimadzu LC-2050 system (Shimadzu, Kyoto, Japan) using a Galaksil EF-C18–H reverse-phase column (120 Å, 5 μm, 10 × 250

(14) Adaptive evolution of electron transfer pathways in Thermoanaerobacterium saccharolyticumJournal of BacteriologyJune 18, 2026João H. T. M. Fabri, Shu Huang, T. Emme Burgin, Luana W. Bergamo, Lee R. Lynd, Daniel G. Olsonsyringe filters. Fermentation substrate and product concentrations were quantified using a Shimadzu LC-2050C high-performance liquid chromatograph (HPLC) coupled to an HPX-87H column and an additional UV detector.

(15) Structural basis and immunogenic efficacy of porcine circovirus type 3 virus-like particleNature CommunicationsJune 16, 2026Jinfu Su, Xiaodan Tong, Yanan Jiang, Yu Li, He Yan, Yan Liu, Yanwei Wang, Xiaorui Su, Zhe Sun, Mengyue Wang, et al.analysis. For high-performance size-exclusion chromatography (HPSEC), purified PCV3 VLPs were analyzed using an LC-2050C high-performance liquid chromatography system (Shimadzu). The mobile phase was PBS, pH 7.2–7.4, filtered

(16) Visualizing cellular G-quadruplexes with a bioinspired chemiluminescent probeNucleic Acids ResJune 12, 2026Pengfei Wang, Xiaoyu Li, Zhichun Wang, Ziyue Guan, Jean-Louis Mergny, Jing Yang, Mingpan Chengmeasurements Chemical stability of PCL and CLA under varied pHs was determined by the HPLC (Shimadzu LC-2050C, Japan). The compounds (100 μM) were added onto the Eppendorf tubes with 0.02 M buffers, which are constructed

(17) A Pyrone Glucoside from Maerua angolensis Induces Caspase-Dependent Apoptosis and Targets AKT1, PARP-1, and Caspase-7 in Triple-Negative Breast CancerBiomoleculesJune 11, 2026Jamila Aminu, Amina Jega Yusuf, Bor-Jang Hwang, Sonia Kamran, Nasiru Abdullahi, Adamu Jibril Alhassan, John Obadipe, Valerie Odero-Marah, Hajjagana Hamza, Abdullahi Ibrahim Uba, et al.(ESI) source operated in positive-ion mode. Analytical HPLC analysis was carried out on a Shimadzu LC-2050C 3D liquid chromatography system (Shimadzu Corporation, Kyoto, Japan) using a reversed-phase C18 column

(18) Synthesis of bundle copolymers as an emergent class of copolymer architectureNat CommunJune 10, 2026Yuki Kametani, Rintaro Yamaguchi, Yusuke Ando, Yuta Kawasaki, Takashi Uemuratreated under reduced pressure (<10−2 Pa) at 393 K overnight. GPC was performed at 40 °C using a Shimadzu LC-2050 liquid chromatograph equipped with two PS gel columns in series (Shodex LF-804) and refractive index

(19) Machine learning combined with population pharmacokinetics: a hybrid model for predicting the plasma concentration of linezolid in critically ill pediatric patientsFront PharmacolJune 2, 2026Yanping Zhang, Lin Zhu, Li Shen, Guangfei Wang, Junqi Zhang, Yang Chen, Yi Wang, Zhiping Liconcentrations were determined using a validated high-performance liquid chromatography (HPLC) method (LC-2050C 3D; Shimadzu Inc.) with ultraviolet detection. The chromatographic column was a Waters XBridge C18 (4.6

(20) A Green and Sustainable Approach for Melatonin Determination: Comparative Assessment of Hybrid Micellar Liquid Chromatography and Differential Pulse VoltammetryACS OmegaJune 2, 2026Zehra Üstün, Ümran Sofu, İlkay Konçe, Ebru Çubuk DemiralayInstrumentation All chromatographic analyses were performed using a Shimadzu i-Series HPLC system (Model LC-2050C 3D, Kyoto, Japan) equipped with a quaternary solvent delivery unit, an autosampler, a column oven with

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