CometSlide from R&D Systems, a Bio-Techne Brand

Product Specs
ItemCometSlide
CompanyR&D Systems, a Bio-Techne Brand
Price $312.00Supplier Page View Company Product Page
Catalog Number4250-200-03
Quantity100 Tests
TypeSlide
StorageStore the unopened product at room temperature. Do not use past expiration date

Specifications/Features

Available conjugates: Sizes Available: 100 Tests

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) DNA damage burden causes selective CUX2 neuron loss in neuroinflammationNatureApril 1, 2026Laura Morcom, Wenlong Xia, Zhaoyang Xu, Yashika Awasthi, Celine Geywitz, Matthew O. Ellis, Tomas Noli, Amel Zulji, Daniel Yamamoto, Gemma C. Girdler, et al.agarose (R&D systems, 4250-050-02) and 75 μl was applied to a single well of a Comet slide (R&D systems, 4250-200-03). The slides were set for 15 min at 4 °C, before being subjected to lysis solution (R&D systems, 4250-050-01)

(2) BTAF1: a key regulator of DNA end resection and predictor of chemotherapy sensitivity in gastric cancerCell death and differentiationMarch 17, 2026Xie JJ, Lin JL, Xiang ZC, Qu CH, Cai XX, Nie RC, Lin P, Yin YX, Duan JL, Xie D, et al.

(3) DNA-damage dependent isoform switching modulates RIF1 DNA repair complex assembly and phase separationThe Journal of biological chemistryDecember 1, 2025Koo AS, Jia W, Kim SH, Scalf M, Boos CE, Chen Y, Wang D, Voter AF, Bajaj A, Smith LM, et al.

(4) The 9-1-1 complex protects ssDNA gaps in BRCA2-deficient cancerbioRxiv : the preprint server for biologyOctober 7, 2025Grimsley HE, Courtemanche K, Cox S, McDermott N, Sharma A, Bright J, Setton J, Orman M, Powell SN.

(5) CLNS1A regulates genome stability and cell cycle progression to control CD4 T cell function and autoimmunityScience ImmunologyJune 20, 2025Liwei Wang, Lucile Noyer, Miki Jishage, Yin-Hu Wang, Anthony Y. Tao, Maxwell McDermott, Ivan Gando, Ikjot Sidhu, Ke Hu, Li Zhong, et al.collected and subjected to comet assay following the manufacturer’s instructions (R&D systems, Cat. No. 4250–200-03). Briefly, cells were embedded in LMAgarose on a CometSlide and treated with lysis solution at 4°C for

(6) Ultrasound-activated cilia for biofilm control in indwelling medical devicesProceedings of the National Academy of SciencesMay 6, 2025Pedro Amado, Cornel Dillinger, Chaimae Bahou, Ali Hashemi Gheinani, Dominik Obrist, Fiona Burkhard, Daniel Ahmed, Francesco ClavicaR&D Systems, 4250-050-02) at 37 °C and immediately pipetted (50 μl) onto CometSlides™ (R&D Systems, 4250-200-03). The mixture was spread evenly, and the slides were placed flat at 4 °C in the dark for 10 min to allow

(7) Combining Multiplexed CRISPR/Cas9-Nickase and PARP Inhibitors Efficiently and Precisely Targets Cancer CellsCancer ResMay 6, 2025Soyoung Lee, Kyunghwan Kim, Hye-Jin Jeong, Subin Choi, Himchan Cheng, Dayoung Kim, Soomin Heo, Jinhee Mun, Minjong Kim, Eunjin Lee, et al.system. Alkaline comet assay The alkaline comet assay was performed using CometSlide (R&D Systems, #4250-200-03) according to the manufacturer’s instructions. Briefly, a cell suspension in cold PBS was mixed with

(8) BET inhibitor and CDK4/6 inhibitor synergistically inhibit breast cancer by suppressing BRD4 stability and DNA damage repairTranslational oncologyJanuary 1, 2025Chi S, Wei F, Li Y, Yu L, Ma C, Fang Y, Yang B, Chen Y, Ding J.

(9) PNKP safeguards stalled replication forks from nuclease-dependent degradation during replication stressCell reportsDecember 24, 2024Mashayekhi F, Ganje C, Caron MC, Heyza JR, Gao Y, Zeinali E, Fanta M, Li L, Ali J, Mersaoui SY, et al.

(10) UHRF1 poly-auto-ubiquitination induced by the anti-cancer drug, thymoquinone, is involved in the DNA repair machinery recruitmentThe international journal of biochemistry & cell biologyJune 1, 2024Almalki NAR, Sabir JSM, Ibrahim A, Alhosin M, Asseri AH, Albiheyri RS, Zari AT, Bahieldin A, Javed A, Mély Y, et al.

(11) Temporal coordination of the transcription factor response to H(2)O(2) stressNature communicationsApril 23, 2024Jose E, March-Steinman W, Wilson BA, Shanks L, Parkinson C, Alvarado-Cruz I, Sweasy JB, Paek AL.

(12) Biotin-conjugated Ru(II) complexes with AIE characteristics as mitochondria-targeted photosensitizers for enhancing photodynamic therapy by disrupting cellular redox balanceEuropean journal of medicinal chemistryJanuary 15, 2024Wei L, He X, Zhao D, Kandawa-Shultz M, Shao G, Wang Y.

(13) Therapeutic targeting of CPSF3-dependent transcriptional termination in ovarian cancerScience advancesNovember 24, 2023Shen P, Ye K, Xiang H, Zhang Z, He Q, Zhang X, Cai MC, Chen J, Sun Y, Lin L, et al.

(14) Prolonged particulate hexavalent chromium exposure induces RAD51 foci inhibition and cytoplasmic accumulation in immortalized and primary human lung bronchial epithelial cellsToxicology and applied pharmacologyNovember 15, 2023Meaza I, Williams AR, Lu H, Kouokam JC, Toyoda JH, Croom-Perez TJ, Wise SS, Aboueissa AE, Wise JP Sr.

(15) Innovative technology for evaluation of sperm DNA double-strand breaks diagnoses male factor infertility and prevents reproductive failuresScientific reportsNovember 3, 2023Wang TE, Lee CI, Huang CC, Tsao HM, Chang HC, Chang LS, Chang TA, Lee MS, Hsu CT.

(16) Repair of topoisomerase 1-induced DNA damage by tyrosyl-DNA phosphodiesterase 2 (TDP2) is dependent on its magnesium bindingThe Journal of biological chemistryAugust 1, 2023Shimizu N, Hamada Y, Morozumi R, Yamamoto J, Iwai S, Sugiyama KI, Ide H, Tsuda M.(4250-050-02, R&D Systems) at 37 °C. Cell suspensions were immediately transferred onto a CometSlide slide (4250-200-03, R&D Systems) and maintained at 4 °C for 10 min. The slides were immersed in prechilled CometAssay Lysis Solution

(17) Efficient bioremediation of laboratory wastewater co-contaminated with PAHs and dimethylformamide by a methylotrophic enrichment cultureJournal of environmental managementJanuary 1, 2023Dhar K, Sivaram AK, Panneerselvan L, Venkateswarlu K, Megharaj M.

(18) NEDDylated Cullin 3 mediates the adaptive response to topoisomerase 1 inhibitorsScience advancesDecember 9, 2022Meroni A, Grosser J, Agashe S, Ramakrishnan N, Jackson J, Verma P, Baranello L, Vindigni A.

(19) Istradefylline protects from cisplatin-induced nephrotoxicity and peripheral neuropathy while preserving cisplatin antitumor effectsJ Clin InvestNovember 15, 2022Edmone Dewaeles, KÃ©vin Carvalho, Sandy Fellah, Jaewon Sim, Nihad Boukrout, Raphaelle Caillierez, Hariharan Ramakrishnan, Cynthia Van der Hauwaert, Jhenkruthi Vijaya Shankara, Nathalie Martin, et al.(1613111, Bio-Rad) 0.5% in PBS at 42°C. The suspension was then immediately spread on a comet slide (4250-200-03, R&D Systems). Agarose was allowed to cool down for 20 minutes at 4°C. Then, cell membranes were permeabilized

(20) Istradefylline protects from cisplatin-induced nephrotoxicity and peripheral neuropathy while preserving cisplatin antitumor effectsJ Clin InvestNovember 15, 2022Edmone Dewaeles, Kévin Carvalho, Sandy Fellah, Jaewon Sim, Nihad Boukrout, Raphaelle Caillierez, Hariharan Ramakrishnan, Cynthia Van der Hauwaert, Jhenkruthi Vijaya Shankara, Nathalie Martin, et al.(1613111, Bio-Rad) 0.5% in PBS at 42°C. The suspension was then immediately spread on a comet slide (4250-200-03, R&D Systems). Agarose was allowed to cool down for 20 minutes at 4°C. Then, cell membranes were permeabilized

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CometSlide from R&D Systems, a Bio-Techne Brand

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R&D Systems, a Bio-Techne Brand

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CometSlide from R&D Systems, a Bio-Techne Brand

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