GelCount™ 2 imager and counter of colonies, organoids and spheroids from Oxford Optronix Ltd.

Product Specs
ItemGelCount^™ 2 imager and counter of colonies, organoids and spheroids
CompanyOxford Optronix Ltd.
Price Get Pricing Get Quote for this Product
Catalog NumberGELCOUNT 2
Dimensions(WxDxH) 615 x 460 x 200 mm
Mode of OperationHigh resolution 16-bit greyscale matrix CCD, white light LED trans-illumination
Operating Temperature15 – 30°C
Electrical RequirementsExternal PSU (100-240V / 50-60 Hz), 24V DC, 2.5A, 60W max
Plate Formats6, 12, 24, 48, 96-well plates; 35 mm, 50 mm, 100 mm Petri dishes
TypeDigital colony counter for cancer cell colonies, spheriods or organoids
TimeTypical acquisition time: 8 mins (four 6-well plates at 1,200 dpi)
Scan AreaApprox. 30 µm (min. colony diameter)
ResolutionImaging resolution: 300 to 2,400 dpi, user selectable
QuantityEA

Specifications/Features

Second-generation imaging and analysis platform for 3D cell colonies, spheroids and organoids in multi-well plates and Petri dishes High-resolution whole well or whole dish view, no z-stacking Substantial throughput and objectivity benefits over manual microscope counting Generate object counts AND diameter statistics per well or dish Direct exportation of output data to Excel® Unlimited software installations for image processing on other workstations

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Oxford Optronix Ltd.

9 & 10 Somerville Court

Trinity Way

Banbury Business Park, Adderbury OX17 3SN

United Kingdom

Phone: +44 (0)1235 821 803

Email: sales@oxford-optronix.com
info@oxford-optronix.com
support@oxford-optronix.com

Company Profile

Website: www.oxford-optronix.com

(1) CDX2 loss in colorectal cancer cells is associated with invasive properties and tumor buddingSci RepJuly 6, 2025Nils Bodmer, Kristin Uth, Rina Mehmeti, Cansaran Saygili Demir, Deborah Stroka, Nassim Ghaffari-Tabrizi-Wizsy, Alessandro Lugli, Olivier de Wever, Inti Zlobec, Mario P. TschanPBS, once with distilled water, then dried overnight. Colonies were counted using an Oxford Optronix Gelcount TM apparatus (Oxford Optronix, UK). Wound-healing assays Wound healing: CaCo2 cells and the respective

(2) BCL2 drives castration resistance in castration-sensitive prostate cancer by orchestrating reciprocal crosstalk between oncogenic pathwaysCell ReportsJune 24, 2025Rahim Hirani, Subhiksha Nandakumar, Nabila Zaman, Prathiksha Prabhakaraalva, Sarah Ann King, Teja Muralidhar Kalidindi, Romina Ghale, Sai Harisha Rajanala, Deborah C. Fidele, Elisa De Stanchina, et al.treated with 10 μM ENZA or an equivalent amount of DMSO for two weeks. Tumorspheres were counted using GelCount 2 (Oxford Optronix) and photographed under a microscope at 50x magnification. Six wells were used for

(3) Inter-Relationship Between Melanoma Vemurafenib Tolerance Thresholds and Metabolic Pathway ChoiceCellsJune 18, 2025Pratima Nangia-Makker, Madison Ahrens, Neeraja Purandare, Siddhesh Aras, Jing Li, Katherine Gurdziel, Hyejeong Jang, Seongho Kim, Malathy P Shekharform for two to three weeks and detected by crystal violet staining. Colonies were quantified using GelCount™ Oxford Optronix and the CHARM algorithm (Oxford Optronics, Ltd., London, ON, Canada), with a minimum

(4) S- and R-Carvedilol Prevent Benzo(a)pyrene-Induced Lung CarcinogenesisThorac CancerJune 18, 2025Ayaz Shahid, Steven Yeung, Bradley T. Andresen, Ying HuangColonies larger than ten cells were counted under a microscope, and images were captured using the GelCount imaging system (Oxford Optronix, Abingdon, United Kingdom). 2.5 Dual‐Luciferase Reporter Assay A dual‐luciferase reporter assay

(5) High-throughput 3D spheroid screens identify microRNA sensitizers for improved thermoradiotherapy in locally advanced cancersMolecular Therapy Nucleic AcidsJune 10, 2025MengFei Xu, Mark A. van de Wiel, Dominika Martinovičová, Angelina Huseinovic, Victor W. van Beusechem, Lukas J.A. Stalpers, Arlene L. Oei, Renske D.M. Steenbergen, Barbara C. Snoekcrystal violet in 10% ethanol, 50% methanol, and 40% water) followed by scanning and counting with GelCount (Oxford Optronix, Abington, UK). Plating efficiencies were defined by dividing the amount of counted

(6) Targeting BATF2-RGS2 axis reduces T-cell exhaustion and restores anti-tumor immunityMol CancerMay 30, 2025Xuyu Gu, Chanchan Gao, Xiangyu Su, Yaoyao Zhu, Qiyu Fang, Jia Yu, Ziming Wang, Deping Zhao, Wentian Zhangincluded 0.5% crystal violet/20% methanol/PBS. The number of colonies was measured with Oxford Optronix-GELCOUNT. EdU labeling assay Cells were resuspended in 500 ul and seeded into a 24-well plate at a ratio of

(7) Co-inhibition of Notch1 and ChK1 triggers genomic instability and melanoma cell death increasing the lifespan of mice bearing melanoma brain metastasisJournal of experimental & clinical cancer research : CRMay 28, 2025Thakur V, Thakur VS, Wang D, de Freitas JT, Bianchi A, Nivelo LA, Umland O, Welford SM, Bedogni B.nM) or both. After 10–12 days incubation, colonies were stained with crystal violet and scored using GelCount (Oxford Optronix) as previously described [15]. DNA fiber assay DNA fiber assay to determine replication

(8) FOXA2 promotes metastatic competence in small cell lung cancerNat CommunMay 26, 2025Kenta Kawasaki, Sohrab Salehi, Yingqian A. Zhan, Kevin Chen, Jun Ho Lee, Eralda Salataj, Hong Zhong, Parvathy Manoj, Dennis Kinyua, Barbara P. Mello, et al.Doxycycline was added from day1 and replenished every 48 hr. The images were taken using an Oxford Optronix Gelcount instrument and the number of formed clusters was counted. Cell proliferation assays were performed with

(9) Substituted benzylamino-2'-deoxyadenosine a modified nucleoside with radiosensitizing propertiesScientific reportsMay 20, 2025Datta M, Szczyrba A, Czaja A, Zdrowowicz M, Demkowicz S, Rak J.(v/v) glutaraldehyde and 0.5% crystal violet. The stained colonies were evaluated and counted using a GelCount Oxford Optronix automated colony counter. The experiment was conducted in triplicate. The control consisted

(10) Gα13 Promotes Clonogenic Growth by Increasing Tolerance to Oxidative Metabolic Stress in Prostate Cancer CellsInt J Mol SciMay 20, 2025Di Wu, Wei Kiang Lim, Xiaoran Chai, Veerabrahma Pratap Seshachalam, Suhail Ahmed Kabeer Rasheed, Sujoy Ghosh, Patrick J. Caseytetrazolium bromide (MTT, #M2128, Sigma, St. Louis, MO, USA). Colonies (>40 µm) were counted using GelCount™ (Oxford Optronix Ltd., Abingdon, UK) using a 24-well plate mask at 2400 DPI resolution and CHARM settings

(11) Targeting YY1-DR5 Axis by Pyripyropene O as a Novel Therapeutic Strategy Against Prostate Cancer: Molecular Mechanisms and In Vivo Zebrafish ValidationMar DrugsMay 19, 2025Wenxuan Fang, Ying Chen, Mingyi Nie, Xuefeng Zhou, Yonghong Liu, Huaming Tao, Bin Yang, Xueni Wang4% tissue fixative, stained with crystal violet, and analyzed for the number of colonies using the GelCount system (GelCount, Oxford Optronix). For three-dimensional sphere formation analysis, 200 μL of a mixed

(12) AXL promotes inflammatory breast cancer progression by regulating immunosuppressive macrophage polarizationBreast Cancer ResMay 6, 2025Lan T. H. Phi, Yating Cheng, Yohei Funakoshi, Francois Bertucci, Pascal Finetti, Steven J. Van Laere, Fang Zou, James P. Long, Suguru Ogata, Savitri Krishnamurthy, et al.Spheres were stained with MTT (0.4 mg/ml), and the spheres larger than 80 μm were quantified using GelCount scanning software (Oxford Optronix, Oxford, UK). Cell growth assay Cancer cells were plated in 96-well

(13) Identification of a TNIK-CDK9 Axis as a Targetable Strategy for Platinum-Resistant Ovarian CancerMolecular Cancer TherapeuticsApril 2, 2025Noah Puleo, Harini Ram, Michele L. Dziubinski, Dylan Carvette, Jessica Teitel, Sreeja C. Sekhar, Karan Bedi, Aaron Robida, Michael M. Nakashima, Sadaf Farsinejad, et al.(Corning). Treatment was added to spheres 3 days after plating and imaged 7 days after treatment using a GelCount: mammalian cell colony, spheroid and organoid counter (Oxford Optronix; https://www.oxford-optronix.com/gelcount-cell-colony-counter;

(14) The Combination of Temporal and Spatial Dose Fractionation in Microbeam Radiation TherapyBiomedicinesMarch 10, 2025Jessica Stolz, Kristina Rogal, Sandra Bicher, Johanna Winter, Mabroor Ahmed, Susanne Raulefs, Stephanie E. Combs, Stefan H. Bartzsch, Thomas E. Schmidwith crystal violet (Crystal-Violet, TUM University Hospital, Munich, Germany) and analyzed with the GelCount™ (GelCount™, Oxford Optronix, Abingdon, UK). A colony was counted if it consisted of at least 50 cells.

(15) Biguanides antithetically regulate tumor properties by the dose-dependent mitochondrial reprogramming-driven c-Src pathwayCell Rep MedFebruary 18, 2025Jun Hyoung Park, Kwang Hwa Jung, Dongya Jia, Sukjin Yang, Kuldeep S. Attri, Songyeon Ahn, Divya Murthy, Tagari Samanta, Debasmita Dutta, Meron Ghidey, et al.were seeded onto top agar of six-well plates. Colonies were counted at different intervals using the GelCount colony counting system (Oxford Optronix) according to the manufacturer’s instructions. Mammosphere

(16) Preparation and Characterization of an Engineered FGF1 Conjugated to 161Tb for Targeting of FGFRsACS OmegaFebruary 18, 2025Linlin Song, Michal Kostas, Jon K. Laerdahl, Marie Skálová, Tereza Janská, Asta Juzeniene, Svein Ræstad, Alexander Krivokapic, Georgios N. Kalantzopoulos, Jaroslav Soltes, et al.washed with PBS three times, and dried at room temperature for 1 h. Colony images were captured by a GelCount (OXFORD OPTRONIX). To assess the survival fraction of eFGF1-161Tb, stained colonies were dissolved in

(17) An Autophagy-Targeting Chimera Induces Degradation of Androgen Receptor Mutants and AR-v7 in Castration-Resistant Prostate CancerCancer researchJanuary 15, 2025Bae TH, Sung KW, Pham TM, Najy AJ, Zamiri A, Jang H, Mun SR, Kim S, Kwon HK, Son YS, et al.fixed with 70% ethanol and stained with 1% crystal violet. The colonies were imaged and counted using GelCount (Oxford Optronix Ltd.) Subcellular fractionation The subcellular fractionation of 22Rv1 was conducted

(18) NOS inhibition sensitizes metaplastic breast cancer to PI3K inhibition and taxane therapy via c-JUN repressionNature communicationsDecember 30, 2024Reddy T, Puri A, Guzman-Rojas L, Thomas C, Qian W, Zhou J, Zhao H, Mahboubi B, Oo A, Cho YJ, et al.(Stem Cells) in low-adherent 6-well and 24-well plates. Mammospheres were imaged and counted using GelCount imaging and software system (Oxford Optronix Ltd.). For secondary MSFE, mammospheres were collected,

(19) Bestrophin-4 relays HES4 and interacts with TWIST1 to suppress epithelial-to-mesenchymal transition in colorectal cancer cellseLifeDecember 19, 2024Zijing Wang, Bihan Xia, Shaochong Qi, Xian Zhang, Xiaoshuang Zhang, Yan Li, Huimin Wang, Miao Zhang, Ziyi Zhao, David Kerr, et al.stained with crystal violet (0.005% in 20% methanol). The numbers of colonies were quantified using GelCount (Oxford Optronix Ltd, Oxford, UK). The assay was carried out in triplicate wells for three independent

(20) Drug repurposing screen targeting PARP identifies cytotoxic activity of efavirenz in high-grade serous ovarian cancerMol Ther OncolDecember 19, 2024Matthews B, Wong-Brown M, Liu D, Yee C, Dickson KA, Schneider J, Islam S, Head R, Martin JH, Ford CE, et al.stained with 0.25% w/v crystal violet in 25% v/v methanol for 5 min.48 Colonies were counted using the GelCount imager (Oxford Optronix, Abingdon, England) and plating efficiency (PE) and surviving fraction (SF)

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2/23/2015Couldn't do without it Dominic JamesI work in drug discovery and use colony formation assays, mainly in 6-well plates, to determine the effect of compounds on the clonogenic potential of cells. I have examined both the effect of a ... Read Review

GelCount^™ 2 imager and counter of colonies, organoids and spheroids

GelCount^™ 2 imager and counter of colonies, organoids and spheroids from Oxford Optronix Ltd.

Description

Specifications/Features

Oxford Optronix Ltd.

Citations (494)

Reviews

GelCount^™ 2 imager and counter of colonies, organoids and spheroids from Oxford Optronix Ltd.

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