Brefeldin A from Cayman Chemical

Product Specs
ItemBrefeldin A
CompanyCayman Chemical
Price $71.00Supplier Page View Company Product Page
Catalog Number11861
Quantity10 mg
Research AreaCell Biology, Endomembrane System & Vesicular Trafficking
FormatA crystalline solid
Molecular Weight280.4
Purity≥98%
TypeInhibitors
OriginUSA
FormulaC16H24O4
Storage-20

Add to Compare List

Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) A PI(3,5)P2/CHMP4B axis on lysosomes is essential for microautophagic degradation of STINGNat CommunMay 27, 2026Tsumugi Shoji, Ayumi Shinojima, Takuma Kishimoto, Kanako Sato, Nana Ikegami, Eisuke Yumoto, Ruri Shindo, Yasunori Uchida, Satoshi Kusumi, Daisuke Koga, et al.from the manufacturers as noted: DMXAA (14617, Cayman), bafilomycin A1 (11038, Cayman), brefeldin A (11861, Cayman), Custom Kinase Screening Library (9003376, Cayman), apilimod (HY-14644, MCH MedChemExpress

(2) Hypoxia Impairs CD8+ T Cell Fitness and Is Associated with a Dysfunctional CD8+ T Cell State in Pancreatic CancerCancers (Basel)May 8, 2026Ashley M. Mello, Marina Pasca di Magliano, Kyoung Eun LeeCayman Chemical, Ann Arbor, MI, USA), ionomycin (0.5 μg/mL, #11932, Cayman Chemical), and Brefeldin A (10 μg/mL, #11861, Cayman Chemical). For the proliferation assays, naive CD8+ T cells were loaded with 5 µM carboxyfluorescein

(3) Aromatic microbial metabolite hippuric acid enhances inflammatory responses in macrophages via TLR-MyD88 signaling and lipid remodelingCell ReportsJanuary 27, 2026Gauri Mirji, Sajad Ahmad Bhat, Mohamed El El Sayed, Sarah Kim Reiser, Siva Pushpa Gavara, Ying Ye, Taito Miyamoto, Wujuan Zhang, Peter Vogel, Joel Cassel, et al.True nuclear transcription factor buffer set,BioLegend,Cat# 424401 Ionomycin,MedChemExpress,Cat# HY-13434 Brefeldin A,Cayman chemical,Cat# 11861 Monensin,Cayman chemical,Cat#16488 Phorbol 12-myristate 13-acetate,Cayman chemical,Cat# 10008014 25-Hydroxycholesterol,MedChemExpress,Cat#

(4) LC3 and GABARAP independent autophagy of misfolded procollagen in mouse osteoblastsAutophagySeptember 9, 2025Elena Makareeva, Shakib Omari, Anna M. Roberts-Pilgrim, Laura Gorrell, Bella Radant, Muthulakshmi Sellamani, Edward L. Mertz, Basma Khoury, Kenneth Kozloff, Sergey Leikin50μg/mL leupeptin (Cayman chemicals, 14026) for 6 h or with 10 μg/mL brefeldin A (Cayman chemicals, 11861) for 1 h or 7 h. The treated cells were stained with SiR700-Lysosome kit (Cytoskeleton, CY-SC016), fixed

(5) FVIII Trafficking Dynamics Across Subcellular Organelles Using CRISPR/Cas9 Specific Gene KnockoutsInt J Mol SciJuly 1, 2025Salime El Hazzouri, Rawya Al-Rifai, Nicole Surges, Melanie Rath, Heike Singer, Johannes Oldenburg, Osman El-Maarricells were treated with decreasing concentrations of Brefeldin A (Biomol GmbH/Cayman Chemical, Item No. 11861, Hamburg, Germany) ranging from 1 µg/mL to 0.1 µg/mL for 6 to 12 h. Treatment efficacy was confirmed

(6) DMXL1 promotes recruitment of V1-ATPase to lysosomes upon TRPML1 activationNature Structural & Molecular BiologyJune 17, 2025Chan Lee, Matthew J. G. Eldridge, Miguel A. Gonzalez-Lozano, Thomas Bresnahan, Zachary Niday, Donato Del Camino, Tao Fu, Joao A. Paulo, Magdalene M. Moran, Sophie Helaine, et al.Cayman Chemicals, cat. no. 11308; torin1, Sellekchem, cat. no. S2827; brefeldin A, Cayman Chemicals, cat. no. 11861; pierce anti-HA magnetic beads, Thermo Fisher Scientific, cat. no. 88837; TMTpro 18-plex label reagent

(7) A land plant‐specific VPS13 mediates polarized vesicle trafficking in germinating pollenNew PhytologistDecember 1, 2024Surachat Tangpranomkorn, Yuka Kimura, Motoko Igarashi, Fumiko Ishizuna, Yoshinobu Kato, Takamasa Suzuki, Takuya Nagae, Sota Fujii, Seiji Takayamaimaging of pollen tube after drug treatments, Latrunculin B (LatB; L5288; Sigma) or Brefeldin A (BFA, 11861; Cayman Chemical, Ann Arbor, MI, USA) stock solutions in DMSO were first diluted to 2× working concentration

(8) A TBK1-independent primordial function of STING in lysosomal biogenesisMolecular CellOctober 17, 2024Bo Lv, William A. Dion, Haoxiang Yang, Jinrui Xun, Do-Hyung Kim, Bokai Zhu, Jay Xiaojun Tan(Sigma-Aldrich, # D6898, 1 μg/ml), G150 (Cayman Chemical, #28318, 5 μM), Brefeldin A (Cayman Chemical, #11861, 1 μg/ml), Golgicide A (Cayman Chemical, #18430, 5 μM), Puromycin dihydrochloride (Sigma, # P9620, 1

(9) Endocannabinoids and their receptors modulate endometriosis pathogenesis and immune responseeLifeAugust 9, 2024Lingegowda H, Zutautas KB, Wei Y, Yolmo P, Sisnett DJ, McCallion A, Koti M, Tayade C.simulate a sterile inflammatory challenge. Following a 48 hr incubation period, brefeldin A [(10 μg/ml), (11861, Cayman Chemicals, USA)] was introduced to the cells to measure intracellular interferon-gamma (IFNγ)

(10) Targeting dermatophyte Cdc42 and Rac GTPase signaling to hinder hyphal elongation and virulenceiScienceJune 21, 2024Masaki Ishii, Yasuhiko Matsumoto, Tsuyoshi Yamada, Hideko Uga, Toshiaki Katada, Shinya Ohata,Cayman Chemical Company,Cat#17694 Ketorolac,Cayman Chemical Company,Cat#9001148 Brefeldin A,Cayman Chemical Company,Cat#11861 NAV2729,TOCRIS Bioscience,Cat#5986 TrRac,This paper,N/A TrCdc42-His,This paper,N/A TrCdc24 DH-PH,This

(11) Modulation of Paracellular Permeability in SARS-CoV-2 Blood-to-Brain TranscytosisVirusesMay 15, 2024Taylor E. Martinez, Karthick Mayilsamy, Shyam S. Mohapatra, Subhra MohapatraUSA)","Binds to cholesterol, a component of caveolae, and disrupts caveolar formation." Brefeldin A,"11861; Cayman Chemical (Ann Arbor, MI, USA)",Causes fragmentation of the Golgi apparatus. Monensin (sodium salt

(12) Perinuclear damage from nuclear envelope deterioration elicits stress responses that contribute to LMNA cardiomyopathyScience AdvancesMay 10, 2024Kunal Sikder, Elizabeth Phillips, Zhijiu Zhong, Nadan Wang, Jasmine Saunders, David Mothy, Andrew Kossenkov, Timothy Schneider, Zuzana Nichtova, Gyorgy Csordas, et al.concentrations of thapsigargin (Cayman Chemical, catalog no. 10522), BFA (Cayman Chemical, catalog no. 11861), tunicamycin (Cayman Chemical, catalog no. 11445), monensin (Cayman Chemical, catalog no. 16488), golgicide A

(13) IFN-λ drives distinct lung immune landscape changes and antiviral responses in human metapneumovirus infectionmBioMay 8, 2024Jorna Sojati, Olivia B. Parks, Yu Zhang, Sara Walters, Jie Lan, Taylor Eddens, Dequan Lou, Li Fan, Kong Chen, Tim D. Oury, et al.injected 18 h post-infection intraperitoneally (I.P.) with 250 µg brefeldin A (Cayman Chemicals; catalog #11861) reconstituted in dimethyl sulfoxide (DMSO). At 24 h post-infection, lung tissue was isolated and processed

(14) IRE1 signaling increases PERK expression during chronic ER stressCell Death & DiseaseApril 18, 2024Gideon Ong, Rosemund Ragetli, Katarzyna Mnich, Bradley W. Doble, Wafa Kammouni, Susan E. Logue1:1000), XBP1s (BioLegend, 9D11A43, 1:1000). Tunicamycin (11445), Thapsigargin (10522), Brefeldin A (11861) were acquired from Cayman Chemicals. MKC8866 was purchased from CSNPharm (CSN23751) or AmBeed (A1003533).

(15) Phospholipids with two polyunsaturated fatty acyl tails promote ferroptosisCellFebruary 29, 2024Baiyu Qiu, Fereshteh Zandkarimi, Carla T. Bezjian, Eduard Reznik, Rajesh Kumar Soni, Wei Gu, Xuejun Jiang, Brent R. StockwellS8254), ONO-RS-082 (Cayman Chemical 20243), CCCP (Cayman Chemical 25458), brefeldin A (Cayman Chemical 11861), thapsigargin (Cayman Chemical 10522), mitoquinone mesylate (Cayman Chemical 29317), decylubiquinone

(16) Hepatic SEL1L-HRD1 ER-associated degradation regulates systemic iron homeostasis via ceruloplasminProceedings of the National Academy of Sciences of the United States of AmericaJanuary 10, 2023Thepsuwan P, Bhattacharya A, Song Z, Hippleheuser S, Feng S, Wei X, Das NK, Sierra M, Wei J, Fang D, et al.degradation of endogenous CP, cells were pretreated with 1 μg/mL brefeldin A (BFA, Cayman Chemical 11861) for 30 min, then treated with vehicle or 150 μM cycloheximide (CHX, Sigma 01810) for 2 or 4 h. To induce

(17) Single-cell monitoring of dry mass and dry mass density reveals exocytosis of cellular dry contents in mitosiseLifeMay 10, 2022Teemu P Miettinen, Kevin S Ly, Alice Lam, Scott R Manalisdrug",Vacuolin-1,Cayman Chemical,Cat#20425; CAS:351986-85-1, "Chemical compound, drug",Brefeldin A,Cayman Chemical,Cat#11861; CAS:20350-15-6, Antibody,Anti-LAMP-1 conjugated to Alexa Fluor 488 (rat monoclonal),Thermo Fisher Scientific

(18) Single-cell monitoring of dry mass and dry mass density reveals exocytosis of cellular dry contents in mitosisElifeMay 10, 2022Teemu P Miettinen, Kevin S Ly, Alice Lam, Scott R Manalisdrug",Vacuolin-1,Cayman Chemical,Cat#20425; CAS:351986-85-1, "Chemical compound, drug",Brefeldin A,Cayman Chemical,Cat#11861; CAS:20350-15-6, Antibody,Anti-LAMP-1 conjugated to Alexa Fluor 488 (rat monoclonal),Thermo Fisher Scientific

(19) Specific association of TBK1 with the trans-Golgi network following STING stimulationCell Structure and FunctionMarch 8, 2022Haruka Kemmoku, Yoshihiko Kuchitsu, Kojiro Mukai, Tomohiko Taguchipurchased from the manufacturers as noted: DMXAA (14617, Cayman); Nocodazole (13857, Cayman); Brefeldin A (11861, Cayman); MRT67307 (19916, Cayman). PCR cloning N-terminal mNeonGreen- or EGFP -tagged mouse STING

(20) The activity of disease-causative STING variants can be suppressed by wild-type STING through heterocomplex formationFrontiers in cell and developmental biologyJanuary 1, 2022Shindo R, Kuchitsu Y, Mukai K, Taguchi T.days (4321, Peptide Institute), pepstatinA (4397, Peptide Institute), DMXAA (D5235, Vadimezan), BFA (11861, Cayman). Cell culture HEK293T cells were purchased from the American Type Culture Collection (ATCC).

Be the First to Write a Review!

Brefeldin A from Cayman Chemical

Description

Cayman Chemical

Citations (31)

Reviews

Brefeldin A from Cayman Chemical

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map