SB 415286 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemSB 415286
CompanyTocris Bioscience, a Bio-Techne Brand
Price $264.00Supplier Page View Company Product Page
Catalog Number1617/10
Purity98%
Molecular Weight359.73
Molecule Name3-[(3-Chloro-4-hydroxyphenyl)amino]-4-(2-nitrophenyl)-1H-pyrrole-2,5-dione
FormulaC16H10ClN3O5
StorageStore at RT
Quantity10 mg (also 50 mg)

Sizes Available: 10 mg (also 50 mg)

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

(1) mTOR-dependent phosphorylation controls TFEB nuclear exportNature communicationsAugust 17, 2018Napolitano G, Esposito A, Choi H, Matarese M, Benedetti V, Di Malta C, Monfregola J, Medina DL, Lippincott-Schwartz J, Ballabio A.

(2) Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytesJournal of neuroinflammationFebruary 26, 2016Liddell JR, Lehtonen S, Duncan C, Keksa-Goldsteine V, Levonen AL, Goldsteins G, Malm T, White AR, Koistinaho J, Kanninen KM.

(3) GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signallingThe Biochemical journalSeptember 1, 2015Stretton C, Hoffmann TM, Munson MJ, Prescott A, Taylor PM, Ganley IG, Hundal HS.

(4) Tau reduction prevents Aβ-induced axonal transport deficits by blocking activation of GSK3βThe Journal of cell biologyMay 11, 2015Vossel KA, Xu JC, Fomenko V, Miyamoto T, Suberbielle E, Knox JA, Ho K, Kim DH, Yu GQ, Mucke L.

(7) Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiationScientific reportsApril 10, 2015Wang X, Wei L, Cramer JM, Leibowitz BJ, Judge C, Epperly M, Greenberger J, Wang F, Li L, Stelzner MG, et al.

(8) GSK3β inhibition promotes synaptogenesis in Drosophila and mammalian neuronsPloS oneJanuary 1, 2015Cuesto G, Jordán-Álvarez S, Enriquez-Barreto L, Ferrús A, Morales M, Acebes Á.

(12) Tristetraprolin mediates radiation-induced TNF-α production in lung macrophagesPloS oneJanuary 1, 2013Ray D, Shukla S, Allam US, Helman A, Ramanand SG, Tran L, Bassetti M, Krishnamurthy PM, Rumschlag M, Paulsen M, et al.

(13) Sequential dosing in chemosensitization: targeting the PI3K/Akt/mTOR pathway in neuroblastomaPloS oneJanuary 1, 2013Westhoff MA, Faham N, Marx D, Nonnenmacher L, Jennewein C, Enzenmüller S, Gonzalez P, Fulda S, Debatin KM.

(14) GSK3 is a regulator of RAR-mediated differentiationLeukemiaJune 1, 2012Gupta K, Gulen F, Sun L, Aguilera R, Chakrabarti A, Kiselar J, Agarwal MK, Wald DN.

(20) Molecular imaging of glycogen synthase kinase-3beta and casein kinase-1alpha kinasesAnalytical biochemistryOctober 15, 2010Nyati S, Ranga R, Ross BD, Rehemtulla A, Bhojani MS.

SB 415286