A 803467 from Tocris Bioscience, a Bio-Techne Brand | Biocompare.com

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A 803467

Selective NaV1.8 channel blocker

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Tocris Bioscience, a Bio-Techne Brand for
A 803467

Description

Selective NaV1.8 channel blocker

Product Specs
ItemA 803467
CompanyTocris Bioscience, a Bio-Techne Brand
Price $182.00Supplier Page View Company Product Page
Catalog Number2976/10
Quantity10 mg (also 50 mg)
Purity98%
Molecular Weight357.79
Molecule Name5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)-2-furancarboxamide
FormulaC19H16ClNO4
StorageStore at +4°C

Specifications/Features

Sizes Available: 10 mg (also 50 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) SCN4B acts as a metastasis-suppressor gene preventing hyperactivation of cell migration in breast cancerNature communicationsDecember 5, 2016Bon E, Driffort V, Gradek F, Martinez-Caceres C, Anchelin M, Pelegrin P, Cayuela ML, Marionneau-Lambot S, Oullier T, Guibon R, et al.

(2) CXCL13/CXCR5 enhances sodium channel Nav1.8 current density via p38 MAP kinase in primary sensory neurons following inflammatory painScientific reportsOctober 6, 2016Wu XB, Cao DL, Zhang X, Jiang BC, Zhao LX, Qian B, Gao YJ.

(3) Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-αNature medicineJune 1, 2015Mascanfroni ID, Takenaka MC, Yeste A, Patel B, Wu Y, Kenison JE, Siddiqui S, Basso AS, Otterbein LE, Pardoll DM, et al.

(4) Modeling nociception in zebrafish: a way forward for unbiased analgesic discoveryPloS oneJanuary 1, 2015Curtright A, Rosser M, Goh S, Keown B, Wagner E, Sharifi J, Raible DW, Dhaka A.

(5) Functional upregulation of nav1.8 sodium channels on the membrane of dorsal root Ganglia neurons contributes to the development of cancer-induced bone painPloS oneJanuary 1, 2014Liu XD, Yang JJ, Fang D, Cai J, Wan Y, Xing GG.

(6) Attenuation of autonomic reflexes by A803467 may not be solely caused by blockade of NaV 1.8 channelsNeuroscience lettersMay 24, 2013Stone AJ, Kim JS, Yamauchi K, Ruiz-Velasco V, Kaufman MP.

(7) Common mechanisms of drug interactions with sodium and T-type calcium channelsMolecular pharmacologySeptember 1, 2012Bladen C, Zamponi GW.

(8) Involvement of Nav 1.8 sodium ion channels in the transduction of mechanical pain in a rodent model of osteoarthritisArthritis research & therapyJanuary 7, 2012Schuelert N, McDougall JJ.

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