AICAR from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemAICAR
CompanyTocris Bioscience, a Bio-Techne Brand
Price $171.00Supplier Page View Company Product Page
Catalog Number2840/50
Quantity50 mg
Purity99%
Molecular Weight258.23
Molecule NameN1-(β-D-Ribofuranosyl)-5-aminoimidazole-4-carboxamide
FormulaC9H14N4O5
StorageStore at -20°C

Specifications/Features

Sizes Available: 50 mg

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Metformin inhibits PDGFβ signaling to suppress hyaluronan and cytokine production in thyroid eye diseaseExperimental Eye ResearchJune 1, 2026Farha Husain, Charkira C. Patrick, Elisa Roztocil, Steven E. Feldon, Collynn F. Woeller(Millipore Sigma, Burlington, MA, cat no. 3172405GM) or AICAR (Tocris Bioscience, Bristol, UK, cat no. 2840/50) for 1 hour before the addition of PDGFβ. 2.2 Determination of the HA levels via agarose gel electrophoresis Conditioned

(2) Bisphenol A Induces Agrp Gene Expression in Hypothalamic Neurons through a Mechanism Involving ATF3NeuroendocrinologyJanuary 1, 2021Loganathan N, McIlwraith EK, Belsham DD.Tocris Bioscience (Cedarlane, Burlington, ON, Canada). 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR; cat. 2840/50) was purchased from Tocris Bioscience, dissolved in H2O to 50 mM, and diluted 1:100 in medium for a

(3) AMP-Activated Protein Kinase Is Essential for the Maintenance of Energy Levels during Synaptic ActivationiScienceNovember 30, 2018Marinangeli C, Didier S, Ahmed T, Caillerez R, Domise M, Laloux C, Bégard S, Carrier S, Colin M, Marchetti P, et al.

(4) EWS-FLI1 reprograms the metabolism of Ewing sarcoma cells via positive regulation of glutamine import and serine-glycine biosynthesisMolecular carcinogenesisOctober 1, 2018Sen N, Cross AM, Lorenzi PL, Khan J, Gryder BE, Kim S, Caplen NJ.

(5) Berberine Attenuated Proliferation, Invasion and Migration by Targeting the AMPK/HNF4α/WNT5A Pathway in Gastric CarcinomaFrontiers in pharmacologyJanuary 1, 2018Hu Q, Li L, Zou X, Xu L, Yi P.

(6) Direct versus indirect actions of ghrelin on hypothalamic NPY neuronsPloS oneJanuary 1, 2017Hashiguchi H, Sheng Z, Routh V, Gerzanich V, Simard JM, Bryan J.

(7) Anti-Inflammatory Effects of Metformin Irrespective of Diabetes StatusCirculation researchAugust 19, 2016Cameron AR, Morrison VL, Levin D, Mohan M, Forteath C, Beall C, McNeilly AD, Balfour DJ, Savinko T, Wong AK, et al.

(8) AMP-activated protein kinase modulates tau phosphorylation and tau pathology in vivoScientific reportsMay 27, 2016Domise M, Didier S, Marinangeli C, Zhao H, Chandakkar P, Buée L, Viollet B, Davies P, Marambaud P, Vingtdeux V.

(9) Role of Inflammatory Signaling in the Differential Effects of Saturated and Poly-unsaturated Fatty Acids on Peripheral Circadian ClocksEBioMedicineMay 1, 2016Kim SM, Neuendorff N, Chapkin RS, Earnest DJ.

(10) Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathwayNature cell biologyApril 1, 2015Mo JS, Meng Z, Kim YC, Park HW, Hansen CG, Kim S, Lim DS, Guan KL.

(11) Mitochondrial complex IV deficiency, caused by mutated COX6B1, is associated with encephalomyopathy, hydrocephalus and cardiomyopathyEuropean journal of human genetics : EJHGFebruary 1, 2015Abdulhag UN, Soiferman D, Schueler-Furman O, Miller C, Shaag A, Elpeleg O, Edvardson S, Saada A.

(12) A cell-autonomous molecular cascade initiated by AMP-activated protein kinase represses steroidogenesisMolecular and cellular biologyDecember 1, 2014Abdou HS, Bergeron F, Tremblay JJ.

(13) Myostatin regulates energy homeostasis in the heart and prevents heart failureCirculation researchJuly 7, 2014Biesemann N, Mendler L, Wietelmann A, Hermann S, Schäfers M, Krüger M, Boettger T, Borchardt T, Braun T.

(14) Transcriptomic analysis reveals inhibition of androgen receptor activity by AMPK in prostate cancer cellsOncotargetJune 15, 2014Jurmeister S, Ramos-Montoya A, Neal DE, Fryer LG.

(15) Reduced oxidative stress contributes to the lipid lowering effects of isoquercitrin in free fatty acids induced hepatocytesOxidative medicine and cellular longevityJanuary 1, 2014Hassan W, Rongyin G, Daoud A, Ding L, Wang L, Liu J, Shang J.

(16) A genetic screen identifies an LKB1-MARK signalling axis controlling the Hippo-YAP pathwayNature cell biologyJanuary 1, 2014Mohseni M, Sun J, Lau A, Curtis S, Goldsmith J, Fox VL, Wei C, Frazier M, Samson O, Wong KK, et al.

(17) AMPKα1 regulates macrophage skewing at the time of resolution of inflammation during skeletal muscle regenerationCell metabolismAugust 6, 2013Mounier R, Théret M, Arnold L, Cuvellier S, Bultot L, Göransson O, Sanz N, Ferry A, Sakamoto K, Foretz M, et al.

(18) Calcium release-dependent actin flow in the leading process mediates axophilic migrationThe Journal of neuroscience : the official journal of the Society for NeuroscienceJuly 10, 2013Hutchins BI, Klenke U, Wray S.

(19) Activation of AMPK inhibits cervical cancer cell growth through AKT/FOXO3a/FOXM1 signaling cascadeBMC cancerJuly 3, 2013Yung MM, Chan DW, Liu VW, Yao KM, Ngan HY.

(20) Moderate excess of pyruvate augments osteoclastogenesisBiology openApril 15, 2013Fong JE, Le Nihouannen D, Tiedemann K, Sadvakassova G, Barralet JE, Komarova SV.

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7/24/2019AICAR Inhibits LPS-Mediated Energy Depletion Chintan KoyaniAICAR can be used to study AMPK signaling in various cells.

AICAR

AICAR from Tocris Bioscience, a Bio-Techne Brand

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Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

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AICAR from Tocris Bioscience, a Bio-Techne Brand

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