IKK 16 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemIKK 16
CompanyTocris Bioscience, a Bio-Techne Brand
Price $343.00Supplier Page View Company Product Page
Catalog Number2539/10
Purity98%
Molecular Weight520.09
Molecule NameN-(4-Pyrrolidin-1-yl-piperidin-1-yl)-[4-(4-benzo[b]thiophen-2-yl-pyrimidin-2-ylamino)phenyl]carboxamide hydrochloride
FormulaC28H29N5OS.HCl
StorageDesiccate at -20°C
Quantity10 mg (also 50 mg)

Sizes Available: 10 mg (also 50 mg)

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

(1) Inhibition of IκB Kinase at 24 Hours After Acute Kidney Injury Improves Recovery of Renal Function and Attenuates FibrosisJournal of the American Heart AssociationJuly 3, 2017Johnson FL, Patel NSA, Purvis GSD, Chiazza F, Chen J, Sordi R, Hache G, Merezhko VV, Collino M, Yaqoob MM, et al.

(2) Profiling drugs for rheumatoid arthritis that inhibit synovial fibroblast activationNature chemical biologyJanuary 1, 2017Jones DS, Jenney AP, Swantek JL, Burke JM, Lauffenburger DA, Sorger PK.

(5) Inhibition of IκB Kinase Attenuates the Organ Injury and Dysfunction Associated with Hemorrhagic ShockMolecular medicine (Cambridge, Mass.)June 18, 2015Sordi R, Chiazza F, Johnson FL, Patel NS, Brohi K, Collino M, Thiemermann C.

(6) IKK regulates the deubiquitinase CYLD at the postsynaptic densityBiochemical and biophysical research communicationsJuly 18, 2014Thein S, Pham A, Bayer KU, Tao-Cheng JH, Dosemeci A.

(7) Norepinephrine potentiates proinflammatory responses of human vaginal epithelial cellsJournal of neuroimmunologyJune 15, 2013Brosnahan AJ, Vulchanova L, Witta SR, Dai Y, Jones BJ, Brown DR.

(8) Small-molecule inducer of β cell proliferation identified by high-throughput screeningJournal of the American Chemical SocietyFebruary 6, 2013Shen W, Tremblay MS, Deshmukh VA, Wang W, Filippi CM, Harb G, Zhang YQ, Kamireddy A, Baaten JE, Jin Q, et al.

(1)

7/24/2019IKK 16 Blocks LPA-Mediated COX-2 Expression Peter Frankl.IKK 16 can be used to investigate IkB signaling.
(1)

4/22/2019IKK 16 Blocks LPA-mediated COX-2 Expression Chintan KoyaniIKK 16 abolished LPA-induced COX-2 expression in human osteosarcoma cells.

IKK 16