PD 184352 from Tocris Bioscience, a Bio-Techne Brand | Biocompare.com

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PD 184352

Selective MEK inhibitor

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Tocris Bioscience, a Bio-Techne Brand for
PD 184352

Description

Selective MEK inhibitor

Product Specs
ItemPD 184352
CompanyTocris Bioscience, a Bio-Techne Brand
Price $335.00Supplier Page View Company Product Page
Catalog Number4237/10
Quantity10 mg (also 50 mg)
Molecular Weight478.66
Molecule Name2-[(2-Chloro-4-iodophenyl)amino]-N-cyclopropylmethoxy)-3,4-difluorobenzamide
FormulaC17H14ClF2IN2O2
StorageStore at +4°C
Purity98%

Specifications/Features

Sizes Available: 10 mg (also 50 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Phosphoinositide 3-kinase p110α negatively regulates thrombopoietin-mediated platelet activation and thrombus formationCellular signallingOctober 1, 2018Blair TA, Moore SF, Walsh TG, Hutchinson JL, Durrant TN, Anderson KE, Poole AW, Hers I.

(2) Activation of protein synthesis in mouse uterine epithelial cells by estradiol-17β is mediated by a PKC-ERK1/2-mTOR signaling pathwayProceedings of the National Academy of Sciences of the United States of AmericaMarch 17, 2015Wang Y, Zhu L, Kuokkanen S, Pollard JW.

(3) miR-155 induced transcriptome changes in the MCF-7 breast cancer cell line leads to enhanced mitogen activated protein kinase signalingGenes & cancerSeptember 1, 2014Martin EC, Krebs AE, Burks HE, Elliott S, Baddoo M, Collins-Burow BM, Flemington EK, Burow ME.

(4) Central role for protein kinase C in oxytocin and epidermal growth factor stimulated cyclooxygenase 2 expression in human myometrial cellsBMC research notesJune 10, 2014Wouters E, Hudson CA, McArdle CA, Bernal AL.

(5) Subtype-specific MEK-PI3 kinase feedback as a therapeutic target in pancreatic adenocarcinomaMolecular cancer therapeuticsOctober 1, 2013Mirzoeva OK, Collisson EA, Schaefer PM, Hann B, Hom YK, Ko AH, Korn WM.

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8/8/2019Investigating the Role of ERK Pathway in Microglia (Tocris) Joanna PlastiraA selective and orally active MEK inhibitor.