Marimastat from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemMarimastat
CompanyTocris Bioscience, a Bio-Techne Brand
Price $205.00Supplier Page View Company Product Page
Catalog Number2631/1
Quantity1 mg (also 10 mg)
Purity98%
Molecular Weight331.41
Molecule Name(2S,3R)-N4-[(1S)-2,2-Dimethyl-1-[(methylamino)carbonyl]propyl]-N1,2-dihydroxy-3-(2-methylpropyl)butanediamide
FormulaC15H29N3O5
StorageStore at -20°C

Specifications/Features

Sizes Available: 1 mg (also 10 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Cell fate coordinates mechano-osmotic forces in intestinal crypt formationNature cell biologyJuly 1, 2021Yang Q, Xue SL, Chan CJ, Rempfler M, Vischi D, Maurer-Gutierrez F, Hiiragi T, Hannezo E, Liberali P.GM6001(MMP inhibitor, R&D Systems cat# 2983/10), or 0.3 μM Marimastat (MMP inhibitor, R&D Systems cat# 2631/1) or 5 μM DMSO in ENR medium, from 72 hours until fixation at 96 hours. Organoid immunostaining and

(2) Bimodal fluorogenic sensing of matrix proteolytic signatures in lung cancerOrganic & biomolecular chemistryNovember 7, 2018Megia-Fernandez A, Mills B, Michels C, Chankeshwara SV, Krstajić N, Haslett C, Dhaliwal K, Bradley M.

(3) Matrix mechanical plasticity regulates cancer cell migration through confining microenvironmentsNature communicationsOctober 8, 2018Wisdom KM, Adebowale K, Chang J, Lee JY, Nam S, Desai R, Rossen NS, Rafat M, West RB, Hodgson L, et al.

(4) Composite regulation of ERK activity dynamics underlying tumour-specific traits in the intestineNature communicationsJune 5, 2018Muta Y, Fujita Y, Sumiyama K, Sakurai A, Taketo MM, Chiba T, Seno H, Aoki K, Matsuda M, Imajo M.

(5) Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewalNature communicationsMarch 14, 2018Rayagiri SS, Ranaldi D, Raven A, Mohamad Azhar NIF, Lefebvre O, Zammit PS, Borycki AG.

(6) The enhanced susceptibility of ADAM-17 hypomorphic mice to DSS-induced colitis is not ameliorated by loss of RIPK3, revealing an unexpected function of ADAM-17 in necroptosisOncotargetFebruary 27, 2018Fuchslocher Chico J, Falk-Paulsen M, Luzius A, Saggau C, Ruder B, Bolik J, Schmidt-Arras D, Linkermann A, Becker C, Rosenstiel P, et al.

(7) Evaluating the potential of endothelial cells derived from human induced pluripotent stem cells to form microvascular networks in 3D culturesScientific reportsFebruary 8, 2018Bezenah JR, Kong YP, Putnam AJ.

(8) Neuroprotective astrocyte-derived insulin/insulin-like growth factor 1 stimulates endocytic processing and extracellular release of neuron-bound Aβ oligomersMolecular biology of the cellOctober 1, 2017Pitt J, Wilcox KC, Tortelli V, Diniz LP, Oliveira MS, Dobbins C, Yu XW, Nandamuri S, Gomes FCA, DiNunno N, et al.

(9) Human stem cells alter the invasive properties of somatic cells via paracrine activation of mTORC1Nature communicationsSeptember 19, 2017Rosner M, Pham HTT, Moriggl R, Hengstschläger M.

(10) Matrix degradability controls multicellularity of 3D cell migrationNature communicationsAugust 29, 2017Trappmann B, Baker BM, Polacheck WJ, Choi CK, Burdick JA, Chen CS.

(11) Adam17 Deficiency Promotes Atherosclerosis by Enhanced TNFR2 Signaling in MiceArteriosclerosis, thrombosis, and vascular biologyFebruary 1, 2017Nicolaou A, Zhao Z, Northoff BH, Sass K, Herbst A, Kohlmaier A, Chalaris A, Wolfrum C, Weber C, Steffens S, et al.

(12) Signaling pathways induced by serine proteases to increase intestinal epithelial barrier functionPloS oneJanuary 1, 2017Lahey KA, Ronaghan NJ, Shang J, Dion SP, Désilets A, Leduc R, MacNaughton WK.

(13) Discovery of an enzyme and substrate selective inhibitor of ADAM10 using an exosite-binding glycosylated substrateScientific reportsDecember 5, 2016Madoux F, Dreymuller D, Pettiloud JP, Santos R, Becker-Pauly C, Ludwig A, Fields GB, Bannister T, Spicer TP, Cudic M, et al.

(14) Mathematical framework for activity-based cancer biomarkersProceedings of the National Academy of Sciences of the United States of AmericaOctober 13, 2015Kwong GA, Dudani JS, Carrodeguas E, Mazumdar EV, Zekavat SM, Bhatia SN.

(15) WISP-2 in human gastric cancer and its potential metastatic suppressor role in gastric cancer cells mediated by JNK and PLC-γ pathwaysBritish journal of cancerSeptember 15, 2015Ji J, Jia S, Jia Y, Ji K, Hargest R, Jiang WG.

(16) SAR Studies of Exosite-Binding Substrate-Selective Inhibitors of A Disintegrin And Metalloprotease 17 (ADAM17) and Application as Selective in Vitro ProbesJournal of medicinal chemistryAugust 13, 2015Knapinska AM, Dreymuller D, Ludwig A, Smith L, Golubkov V, Sohail A, Fridman R, Giulianotti M, LaVoi TM, Houghten RA, et al.

(17) Cleavage/alteration of interleukin-8 by matrix metalloproteinase-9 in the female lower genital tractPloS oneJanuary 1, 2015Zariffard MR, Anastos K, French AL, Munyazesa E, Cohen M, Landay AL, Spear GT.

(18) Nestin depletion induces melanoma matrix metalloproteinases and invasionLaboratory investigation; a journal of technical methods and pathologyDecember 1, 2014Lee CW, Zhan Q, Lezcano C, Frank MH, Huang J, Larson AR, Lin JY, Wan MT, Lin PI, Ma J, et al.

(19) Cellular contractility and extracellular matrix stiffness regulate matrix metalloproteinase activity in pancreatic cancer cellsFASEB journal : official publication of the Federation of American Societies for Experimental BiologyAugust 1, 2014Haage A, Schneider IC.

(20) Functional impact of NOTCH1 mutations in chronic lymphocytic leukemiaLeukemiaMay 1, 2014Arruga F, Gizdic B, Serra S, Vaisitti T, Ciardullo C, Coscia M, Laurenti L, D'Arena G, Jaksic O, Inghirami G, et al.

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Marimastat

Marimastat from Tocris Bioscience, a Bio-Techne Brand

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Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

Citations (32)

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Marimastat from Tocris Bioscience, a Bio-Techne Brand

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