PugNAc, hexosaminidase A and B inhibitor from Abcam

Product Specs
ItemPugNAc, hexosaminidase A and B inhibitor
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab144670
Quantity5 mg, 25 mg
TypeInhibitor, inhibitor
Molecule NamePugnac

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) O-GlcNAcylation with ubiquitination stabilizes METTL3 to promoting HMGB1 degradation to inhibit ferroptosis and enhance gemcitabine resistance in pancreatic cancerMol MedJune 10, 2025Qiuhong Wang, Dong Wei, Chunman Li, Xiawei Yang, Kun Su, Tao Wang, Renchao Zou, Lianmin Wang, Dongyun Cun, Bo Tang, et al.5′-GCACAGAAGTTGCAAGCAA − 3′; siOGT: 5′-GCCUGAUAGAUCUGGCAAUTT-3′; siEIF3H: 5ʹ-GCAACTCTTGGAAGAAATATA-3ʹ. PugNAc (ab144670) was purchased from Abcam; Cycloheximide (S7418) was purchased from Selleck. Actinomycin D (50-76-0)

(2) Genistein inhibits HIF-1α and attenuates high glucose-induced peritoneal mesothelial-mesenchymal transition and fibrosis via the mTOR/OGT pathwayScientific ReportsOctober 17, 2024Jian Wang, Xin Lv, Yao Lin, Ashanjiang Aniwan, Hongyan Liu, Saijun Zhou, Pei Yuconcentration of 2.5%. Various pharmacological agents, including FG-4592 (T2515, TargetMol), PUGNAc (ab144670, Abcam), MG-132 (T2154, TargetMol), MHY1485 (HY-B0795, MCE), ICI 182,780 (HY-13636, MCE) and Genistein

(3) O-GlcNAcylation regulates HIF-1α and induces mesothelial-mesenchymal transition and fibrosis of human peritoneal mesothelial cellsHeliyonDecember 1, 2023Jian Wang, Xin Lv, Ashanjiang Aniwan, Hongyan Liu, Yao Lin, Xian Shao, Saijun Zhou, Pei Yu(China). The 4′-6-diamidino-2-phenylindole (DAPI) (C0065) was obtained from Solarbio (China) and PUGNAc (ab144670) was obtained from Abcam. OGT inhibitor OSMI-1 (T16409), MG-132 (T2154) and FG-4592 (T2515) were obtained

(4) O-GlcNAcylation and stablization of SIRT7 promote pancreatic cancer progression by blocking the SIRT7-REGγ interactionCell death and differentiationOctober 1, 2022He X, Li Y, Chen Q, Zheng L, Lou J, Lin C, Gong J, Zhu Y, Wu Y.above cells are tested. Reagents PugNAc, a potent O-GlcNAcase and hexosaminidase A and B inhibitor (ab144670) was purchased from Abcam. Thiamet-G (TMG) is an inhibitor of O-GlcNAcylase (S7213), which potently

(5) A cold-stress-inducible PERK/OGT axis controls TOM70-assisted mitochondrial protein import and cristae formationCell metabolismMarch 2, 2021Latorre-Muro P, O'Malley KE, Bennett CF, Perry EA, Balsa E, Tavares CDJ, Jedrychowski M, Gygi SP, Puigserver P.cocktail,Roche,Cat#4693159001 PhosStop phosphatase inhibitor,Roche,Cat#4906845001 Trichostatin A,Sigma,Cat#T8552 PUGNAc,Abcam,Cat#Ab144670 35S-methionine,Perkin Elmer,Cat#NEG709A 32P-ATP,Perkin Elmer,Cat#BLU002Z "CL316,243",Sigma Aldrich,Cat#C5976 DMEM no glucose

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PugNAc, hexosaminidase A and B inhibitor from Abcam

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PugNAc, hexosaminidase A and B inhibitor from Abcam

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