PR 619, DUB inhibitor from Abcam

Product Specs
ItemPR 619, DUB inhibitor
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab144641
Quantity5 mg, 25 mg
Purity0.99
TypeInhibitor, inhibitor
Molecule Name3,5-Dithiocyanatopyridine-2,6-diamine

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Targeting USP11 counteracts SFTPCI73T -associated interstitial lung disease in hiPSCs-derived alveolar organoids and in vivo modelsTheranosticsMarch 19, 2025Janardhan Keshav Karapurkar, Sripriya Rajkumar, Ji-Hye Jung, Ji-Young Kim, Girish Birappa, D. A. Ayush Gowda, Jencia Carminha Colaco, Bharathi Suresh, Jung-Yun Choi, Sang Hyeon Woo, et al.inhibitor mitoxantrone dihydrochloride (MTX; Sigma-Aldrich, Cat no. M6545-10mg), the DUB inhibitor PR-619 (ab144641, Abcam), CCK-8 assay reagent (Dojindo Molecular Technologies, MD, USA), and 4', 6-diamidino-2-phenylindole

(2) USP28 promotes tumorigenesis and cisplatin resistance by deubiquitinating MAST1 protein in cancer cellsCellular and molecular life sciences : CMLSMarch 18, 2024Karapurkar JK, Colaco JC, Suresh B, Tyagi A, Woo SH, Jo WJ, Ko N, Singh V, Hong SH, Oh SJ, et al.puromycin (Cat. no. 12122530, Gibco), cisplatin (Cat no. P4394, Sigma-Aldrich), the DUB inhibitor PR-619 (ab144641, Abcam), AZ1 USP25/28 inhibitor (Cat. no. 7845, Tocris), CCK-8 assay reagent (Dojindo Molecular Technologies,

(3) CRISPR/Cas9-based genome-wide screening for deubiquitinase subfamily identifies USP1 regulating MAST1-driven cisplatin-resistance in cancer cellsTheranosticsJanuary 1, 2022Tyagi A, Kaushal K, Chandrasekaran AP, Sarodaya N, Das S, Park CH, Hong SH, Kim KS, Ramakrishna S.pimozide (Cat no. P1793, Sigma-Aldrich), lestaurtinib (Cat no. 3395, Tocris), DUB inhibitor, PR-619 (ab144641, Abcam), ubiquitin activating enzyme inhibitor, MLN7243 (also called TAK243, Cat no. HY-100487, MedChemExpress)

(4) Precise Temporal Regulation of Post-transcriptional Repressors Is Required for an Orderly Drosophila Maternal-to-Zygotic TransitionCell ReportsJune 23, 2020Wen Xi Cao et al.GmbH,Cat#AG-CP3–0011-M005 (R)-(+)-limonene,Merck,Cat#8.18407.0500 "PR 619, DUB inhibitor",Abcam,Cat#ab144641 AEBSF,Bioshop,Cat#AEB602 Benzamidine,Bioshop,Cat#BEN666 Pepstatin,Bioshop,Cat#PEP605 Leupeptin,Bioshop,Cat#LEU001 RNase A

(5) Dynamic ubiquitination determines transcriptional activity of the plant immune coactivator NPR1eLifeOctober 7, 2019Skelly MJ, Furniss JJ, Grey H, Wong KW, Spoel SH.200519 Commercial assay or kit GFP-Trap A Chromotek Cat# gta-20 Chemical compound, drug PR-619 Abcam Cat# ab144641 Chemical compound, drug NSC632839 Abcam Cat# ab144599 Chemical compound, drug WP1130 Cayman Chemical Cat#

(6) Polyglutamine tracts regulate beclin 1-dependent autophagyNatureJanuary 1, 0001"Ashkenazi A, Bento CF, Ricketts T, Vicinanza M, Siddiqi F, Pavel M, Squitieri F, Hardenberg MC, Imarisio S, Menzies FM, et al."proteasome inhibitor MG132 (10 µM) and a 10 µM cell-permeable, non-selective DUB inhibitor PR616 (#ab144641, Abcam). Ubiquitinated beclin 1 was purified from cell lysates with anti-FLAG-affinity beads (Sigma,

(7) CRISPR/Cas9-based genome-wide screening of the deubiquitinase subfamily identifies USP3 as a protein stabilizer of REST blocking neuronal differentiation and promotes neuroblastoma tumorigenesisJournal of experimental & clinical cancer research : CRJanuary 1, 0001"Karapurkar JK, Kim MS, Colaco JC, Suresh B, Sarodaya N, Kim DH, Park CH, Hong SH, Kim KS, Ramakrishna S."Selleckchem. Puromycin (Cat. no. 12,122,530) was purchased from Gibco, and the DUB inhibitor PR-619 (ab144641) was purchased from Abcam. The ubiquitin activating enzyme inhibitor MLN7243 (also called TAK243, Cat

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PR 619, DUB inhibitor from Abcam

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PR 619, DUB inhibitor from Abcam

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