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Protein Biochemistry
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G-36
G-36 from Cayman Chemical
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Citations:
(9)
Supplier Page
Supplier Page from
Cayman Chemical for
G-36
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Description
A cell-permeable non-steroidal antagonist of GPER, inhibiting activation by either 17β-estradiol or the GPER-selective agonist LNS 8801 (IC50 = 112 and 165 nM, respectively); has no detectable binding activity to either ERα or ERβ
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
G-36
Company
Cayman Chemical
Price
$128.00
Supplier Page
View Company Product Page
Catalog Number
14397
Quantity
5 mg
Research Area
Endocrinology & Metabolism, Estrogens & Progestins, Hormones & Receptors
Format
A crystalline solid
Molecular Weight
412.3
Purity
≥98%
Storage
-20
Formula
C22H22BrNO2
Origin
USA
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (9)
(1)
LNS8801 inhibits Acute Myeloid Leukemia by Inducing the Production of Reactive Oxygen Species and Activating the Endoplasmic Reticulum Stress Pathway
Cancer Research Communications
August 18, 2023
Inyoung Lee, Miriam Doepner, Jillian Weissenrieder, Ariana D. Majer, Sophia Mercado, Angela Estell, Christopher A. Natale, Pamela J. Sung, J. Kevin Foskett, Martin P. Carroll,
et al.
Kira6
(
Cayman
,
19151
) and PERK
inhibitor
GSK2606414
(
Cayman
,
17376
).
GPER
antagonist G-36 (
Cayman
,
14397
) was used to block
CREB
phosphorylation.
Thapsigargin
(
Cayman
,
10522
) was used as a positive control
(2)
LNS8801 inhibits Acute Myeloid Leukemia by Inducing the Production of Reactive Oxygen Species and Activating the Endoplasmic Reticulum Stress Pathway
Cancer Res Commun
August 18, 2023
Inyoung Lee, Miriam Doepner, Jillian Weissenrieder, Ariana D. Majer, Sophia Mercado, Angela Estell, Christopher A. Natale, Pamela J. Sung, J. Kevin Foskett, Martin P. Carroll,
et al.
Kira6
(
Cayman
,
19151
) and PERK
inhibitor
GSK2606414
(
Cayman
,
17376
).
GPER
antagonist G-36 (
Cayman
,
14397
) was used to block
CREB
phosphorylation.
Thapsigargin
(
Cayman
,
10522
) was used as a positive control
(3)
GRP75-faciliated Mitochondria-associated ER Membrane (MAM) Integrity controls Cisplatin-resistance in Ovarian Cancer Patients
International journal of biological sciences
January 1, 2022
Li J, Qi F, Su H, Zhang C, Zhang Q, Chen Y, Chen P, Su L, Chen Y, Yang Y,
et al
.
Life technologies
. Mito-Tracker Green (C1048) and pluronic F-127 (ST501) were obtained from Beyolife.
MKT-077
(
14397
) was obtained from
Cayman Chemical
.
Percoll
(P8370) was obtained from Solarbio.
Protein A/G PLUS-agarose
(4)
G Protein-Coupled Estrogen Receptor Agonist G-1 Inhibits Mantle Cell Lymphoma Growth in Preclinical Models
Frontiers in oncology
January 1, 2021
Zhou L, Yu T, Yang F, Han J, Zuo B, Huang L, Bai X, Jiang M, Wu D, Chen S,
et al
.
Methods Reagents and Antibodies G-1 (B5455) and
G-15
(B5469) were purchased from APExBIO (Texas, USA).
G-36
(
14397
) was purchased from the
Cayman Chemical Company
(Michigan, USA). N-Acetyl-L-cysteine (NAC) (A9165) and
(5)
Sex steroids regulate skin pigmentation through nonclassical membrane-bound receptors
eLife
April 26, 2016
Christopher A Natale, Elizabeth K Duperret, Junqian Zhang, Rochelle Sadeghi, Ankit Dahal, Kevin Tyler O'Brien, Rosa Cookson, Jeffrey D Winkler, Todd W Ridky
αMSH (
M4135
) were purchased from
Sigma-Aldrich
(St. Louis, MO). G-1 (
10008933
),
G-15
(
14673
) and
G-36
(
14397
) were purchased from
Cayman Chemical
(Ann Arbor, MI). CH2P4 (
2085
) was purchased from
Axon
Medchem (Groningen,
(6)
Sex steroids regulate skin pigmentation through nonclassical membrane-bound receptors
Elife
April 26, 2016
Christopher A Natale, Elizabeth K Duperret, Junqian Zhang, Rochelle Sadeghi, Ankit Dahal, Kevin Tyler O'Brien, Rosa Cookson, Jeffrey D Winkler, Todd W Ridky
αMSH (
M4135
) were purchased from
Sigma-Aldrich
(St. Louis, MO). G-1 (
10008933
),
G-15
(
14673
) and
G-36
(
14397
) were purchased from
Cayman Chemical
(Ann Arbor, MI). CH2P4 (
2085
) was purchased from
Axon
Medchem (Groningen,
(7)
Pharmacologic Activation of the G Protein-Coupled Estrogen Receptor Inhibits Pancreatic Ductal Adenocarcinoma
Cellular and molecular gastroenterology and hepatology
January 1, 0001
"Natale CA, Li J, Pitarresi JR, Norgard RJ, Dentchev T, Capell BC, Seykora JT, Stanger BZ, Ridky TW."
tested by using
MycoAlert Mycoplasma Detection Kit
from
Lonza
(Allendale, NJ). G-1 (
10008933
) and
G-36
(
14397
) were purchased from
Cayman Chemical
(Ann Arbor, MI). Cells were trypsinized by using 0.05% trypsin
(8)
Activation of G protein-coupled estrogen receptor signaling inhibits melanoma and improves response to immune checkpoint blockade
eLife
January 1, 0001
"Natale CA, Li J, Zhang J, Dahal A, Dentchev T, Stanger BZ, Ridky TW."
17b-Estradiol
(E8875) were purchased from
Sigma-Aldrich
(St. Louis, MO, USA). G-1 (
10008933
) and
G-36
(
14397
) were purchased from
Cayman Chemical
(Ann Arbor, MI, USA).
Rp-8-Br-cAMPS
was purchased from
Santa Cruz
(9)
The G-Protein-Coupled Estrogen Receptor Agonist G-1 Inhibits Proliferation and Causes Apoptosis in Leukemia Cell Lines of T Lineage
Frontiers in cell and developmental biology
January 1, 0001
"Torres-López L, Olivas-Aguirre M, Villatoro-Gómez K, Dobrovinskaya O."
(3aS,4R,9bR)-4-(6bromo-1,3-benzodioxol-5-yl)-8-propan-2-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c] quinoline (
14397
), both from
Cayman Chemical
, were dissolved in DMSO. Typically, stock solutions were prepared at a concentration
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G-36 from Cayman Chemical
Supplier Page
View Company Product Page
$128.00
Product Specs
Company Info
Citations
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