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Protein Biochemistry
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NSC 87877
NSC 87877 from Cayman Chemical
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Citations:
(2)
Supplier Page
Supplier Page from
Cayman Chemical for
NSC 87877
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Description
A cell-permeable, potent inhibitor of both SHP-1 and SHP-2 (IC50 = 355 and 318 nM, respectively); much less effective against other protein tyrosine phosphatases and DUSP26
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
NSC 87877
Company
Cayman Chemical
Price
$143.00
Supplier Page
View Company Product Page
Catalog Number
14908
Quantity
50 mg
Research Area
Calcium Mobilization, Cell Biology, Cell Signaling
Format
A crystalline solid
Molecular Weight
459.4
Purity
≥98%
Storage
-20
Formula
C19H13N3O7S2
Origin
USA
Type
Inhibitors
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (2)
(1)
Enhanced mitochondrial fission promotes chemosensitivity via SHP-1 activity in triple-negative breast cancer
Mol Biol Rep
August 25, 2026
Elizabeth K. Croom, Lillian E. Walton, Alessandro J. Bono, Anne Zhang, Brock A. Humphries
mitochondrial fusion. NSC87877, a pan SHP-1/2
inhibitor
, was purchased from
Cayman Chemical Company
(cat:
14908
) and used at 25 μM. Doxorubicin was obtained from Pfizer (New York, NY, USA), salinomycin was purchased
(2)
Enhanced mitochondrial fission inhibits triple-negative breast cancer cell migration through an ROS-dependent mechanism
iScience
June 16, 2023
Humphries BA, Zhang A, Buschhaus JM, Bevoor A, Farfel A, Rajendran S, Cutter AC, Luker GD.
7722-84-1 N-acetyl cysteine,Sigma-Aldrich,Cat# A7250;CAS: 616-91-1 NSC87877,
Cayman Chemical
,Cat#
14908
;CAS: 56990-57-9 MitoTracker Deep Red FM,
ThermoFisher
,Cat#
M22426
Hoechst 33342,
ThermoFisher
,Cat#
H1399
Texas Red-X Phalloidin
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NSC 87877 from Cayman Chemical
Supplier Page
View Company Product Page
$143.00
Product Specs
Company Info
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Reviews
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