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Protein Biochemistry
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PSB 0739
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PSB 0739
Highly potent P2Y12 antagonist
PSB 0739 from Tocris Bioscience, a Bio-Techne Brand
Be the first to write a review!
Citations:
(17)
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Tocris Bioscience, a Bio-Techne Brand for
PSB 0739
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Description
Highly potent P2Y12 antagonist
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
PSB 0739
Company
Tocris Bioscience, a Bio-Techne Brand
Price
$282.00
Supplier Page
View Company Product Page
Catalog Number
3983/10
Quantity
10 mg
Purity
95%
Molecular Weight
609.54
Molecule Name
1-Amino-9,10-dihydro-9,10-dioxo-4-[[4-(phenylamino)-3-sulfophenyl]amino]-2-anthracenesulfonic acid sodium salt
Formula
C26H17N3Na2O8S2
Storage
Desiccate at RT
Specifications/Features
Sizes Available:
10 mg
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Tocris Bioscience, a Bio-Techne Brand
614 McKinley Place N.E.
Minneapolis
,
Minnesota
55413
United States
Phone
: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400
Company Profile
Website:
http://www.tocris.com
Citations (17)
(1)
Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions
The Journal of experimental medicine
March 7, 2022
Császár E, Lénárt N, Cserép C, Környei Z, Fekete R, Pósfai B, Balázsfi D, Hangya B, Schwarcz AD, Szabadits E,
et al
.
(2)
TREM2 regulates purinergic receptor-mediated calcium signaling and motility in human iPSC-derived microglia
eLife
February 22, 2022
Jairaman A, McQuade A, Granzotto A, Kang YJ, Chadarevian JP, Gandhi S, Parker I, Smith I, Cho H, Sensi SL,
et al
.
(3)
The dualistic role of the purinergic P2Y12-receptor in an in vivo model of Parkinson's disease: Signalling pathway and novel therapeutic targets
Pharmacological research
February 1, 2022
Iring A, Tóth A, Baranyi M, Otrokocsi L, Módis LV, Gölöncsér F, Varga B, Hortobágyi T, Bereczki D, Dénes Á,
et al
.
(4)
Involvement of P2Y(12) receptors in a nitroglycerin-induced model of migraine in male mice
British journal of pharmacology
December 1, 2021
Gölöncsér F, Baranyi M, Iring A, Hricisák L, Otrokocsi L, Benyó Z, Sperlágh B.
(5)
Prevention of P2 Receptor-Dependent Thrombocyte Activation by Pore-Forming Bacterial Toxins Improves Outcome in A Murine Model of Urosepsis
International journal of molecular sciences
August 6, 2020
Christensen MG, Johnsen N, Skals M, Hamilton ADM, Rubak P, Hvas AM, Praetorius H.
(6)
Microglia monitor and protect neuronal function through specialized somatic purinergic junctions
Science (New York, N.Y.)
January 31, 2020
Cserép C, Pósfai B, Lénárt N, Fekete R, László ZI, Lele Z, Orsolits B, Molnár G, Heindl S, Schwarcz AD,
et al
.
(7)
Antiplatelet Drug Ticagrelor Enhances Chemotherapeutic Efficacy by Targeting the Novel P2Y12-AKT Pathway in Pancreatic Cancer Cells
Cancers
January 20, 2020
Elaskalani O, Domenichini A, Abdol Razak NB, E Dye D, Falasca M, Metharom P.
(8)
Resident Macrophages Cloak Tissue Microlesions to Prevent Neutrophil-Driven Inflammatory Damage
Cell
April 18, 2019
Uderhardt S, Martins AJ, Tsang JS, Lämmermann T, Germain RN.
(9)
Microglial Ramification, Surveillance, and Interleukin-1β Release Are Regulated by the Two-Pore Domain K
+
Channel THIK-1
Neuron
January 17, 2018
Madry C, Kyrargyri V, Arancibia-Cárcamo IL, Jolivet R, Kohsaka S, Bryan RM, Attwell D.
(10)
Infection of microglia with Porphyromonas gingivalis promotes cell migration and an inflammatory response through the gingipain-mediated activation of protease-activated receptor-2 in mice
Scientific reports
September 18, 2017
Liu Y, Wu Z, Nakanishi Y, Ni J, Hayashi Y, Takayama F, Zhou Y, Kadowaki T, Nakanishi H.
(11)
Protease-activated receptor-4 and purinergic receptor P2Y12 dimerize, co-internalize, and activate Akt signaling via endosomal recruitment of β-arrestin
The Journal of biological chemistry
August 18, 2017
Smith TH, Li JG, Dores MR, Trejo J.
(12)
iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases
Neuron
April 19, 2017
Abud EM, Ramirez RN, Martinez ES, Healy LM, Nguyen CHH, Newman SA, Yeromin AV, Scarfone VM, Marsh SE, Fimbres C,
et al
.
(13)
Inverse agonism at the P2Y12 receptor and ENT1 transporter blockade contribute to platelet inhibition by ticagrelor
Blood
December 8, 2016
Aungraheeta R, Conibear A, Butler M, Kelly E, Nylander S, Mumford A, Mundell SJ.
(14)
Diurnal dynamic behavior of microglia in response to infected bacteria through the UDP-P2Y6 receptor system
Scientific reports
July 21, 2016
Takayama F, Hayashi Y, Wu Z, Liu Y, Nakanishi H.
(15)
The Suramin Derivative NF449 Interacts with the 5-fold Vertex of the Enterovirus A71 Capsid to Prevent Virus Attachment to PSGL-1 and Heparan Sulfate
PLoS pathogens
October 1, 2015
Nishimura Y, McLaughlin NP, Pan J, Goldstein S, Hafenstein S, Shimizu H, Winkler JD, Bergelson JM.
(16)
Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice
PloS one
January 1, 2015
Charolidi N, Schilling T, Eder C.
(17)
Nucleolin down-regulation is involved in ADP-induced cell cycle arrest in S phase and cell apoptosis in vascular endothelial cells
PloS one
January 1, 2014
Wang W, Luo J, Xiang F, Liu X, Jiang M, Liao L, Hu J.
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PSB 0739 from Tocris Bioscience, a Bio-Techne Brand
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$282.00
Product Specs
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