5-Aminothalidomide from Cayman Chemical

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5-Aminothalidomide

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Description

A derivative of (±)-thalidomide; inhibits the proliferation of EA.hy926 endothelial cells (IC50 = 200 µM); an intermediate in the synthesis of a PROTAC c-MET degrader with antiproliferative activity in c-MET-sensitive cancer cells; an intermediate in the synthesis of a thalidomide derivative that reduces clinical scores in a mouse model of EAE