Description
InformationFPL 62064 FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and prostaglandin synthetase (cyclooxygenase, COX) with IC50 of 3.5 µM and 3.1 µM for RBL-1 cytosolic 5-lipoxygenase and seminal vesicle prostaglandin synthetase, respectively. FPL 62064 has potent anti-inflammatory activity.Targetsseminal vesicle prostaglandin synthetase (Cell-free assay); RBL-1 cytosolic 5-LOX (Cell-free assay) 3.1 µM; 3.5 µM