Description
InformationIndophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 nM. Indophagolin antagonizes the purinergic receptor P2X4, P2X1 and P2X3 with IC50 of 2.71 µM, 2.40 µM and 3.49 µM, respectively. Indophagolin also antagonizes the Gq-protein-coupled P2Y4, P2Y6, and P2Y11 receptors with IC50 of 3.4~15.4 µM. Indophagolin has a strong antagonistic effect on serotonin receptor 5-HT6 with IC50 of 1.0 µM