GS 143 from Aladdin Scientific

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GS 143

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Description

GS143 is a selective inhibitor of IκBα ubiquitination with IC50 of 5.2 µM for SCFβTrCP1-mediated IκBα ubiquitylation. GS143 suppresses NF-κB activation and transcription of target genes. GS143 exhibits anti-asthma effect