Description
Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with an IC 50 of 82 nM and 1.7 µM for STAT5b and STAT5a, respectively. Stafib-2 exhibits poor cell permeabilityIn VitroStafib-2 has an extremely high affinity for STAT5b (K i =8.8 nM). Stafib-2 (3-10 µM; 4-48 h) does not show significant activity in K562 and MDA-MB-231 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:IC50: 82 nM (STAT5b)