CL075 from MedChemExpress

Product Specs
ItemCL075
CompanyMedChemExpress
Price $105.00Supplier Page View Company Product Page
Catalog NumberHY-117066
TypeChemical
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Quantity10 mM * 1 mL
Purity99.18%
Research AreaInflammation/Immunology

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(1) Porcine decellularized nerve matrix hydrogel attenuates neuroinflammation after peripheral nerve injury by inhibiting the TLR4/MyD88/NF-κB axisNeural Regeneration ResearchMarch 1, 2026Rui Li, Jianquan Liu, Liuxun Li, Guotian Luo, Xinrong Yuan, Shichao Shen, Yongpeng Shi, Jianlong Wu, Bin Yan, Lei YangTAK242 (MedChemExpress, Monmouth Junction, NJ, USA, Cat# HY-11109), 2 µM CL075 (MedChemExpress, Cat# HY-117066), or 100 µM T6167923 (MedChemExpress, Cat# HY-19744; Additional Figure 3). In the LPS + pDNM-gel group,

(2) Porcine decellularized nerve matrix hydrogel attenuates neuroinflammation after peripheral nerve injury by inhibiting the TLR4/MyD88/NF-κB axisNeural Regen ResNovember 13, 2024Rui Li, Jianquan Liu, Liuxun Li, Guotian Luo, Xinrong Yuan, Shichao Shen, Yongpeng Shi, Jianlong Wu, Bin Yan, Lei YangTAK242 (MedChemExpress, Monmouth Junction, NJ, USA, Cat# HY-11109), 2 µM CL075 (MedChemExpress, Cat# HY-117066), or 100 µM T6167923 (MedChemExpress, Cat# HY-19744; Additional Figure 3). In the LPS + pDNM-gel group,

(3) TLR8, but not TLR7, induces the priming of the NADPH oxidase activation in human neutrophilsJournal of leukocyte biologyJune 1, 2015Makni-Maalej K, Marzaioli V, Boussetta T, Belambri SA, Gougerot-Pocidalo MA, Hurtado-Nedelec M, Dang PM, El-Benna J.

(4) TLR7/8 agonists activate a mild immune response in rabbits through TLR8 but not TLR7VaccineSeptember 29, 2014Lai CY, Liu YL, Yu GY, Maa MC, Leu TH, Xu C, Luo Y, Xiang R, Chuang TH.

(5) Generation of Th1-polarizing dendritic cells using the TLR7/8 agonist CL075Journal of immunology (Baltimore, Md. : 1950)July 1, 2010Spranger S, Javorovic M, Bürdek M, Wilde S, Mosetter B, Tippmer S, Bigalke I, Geiger C, Schendel DJ, Frankenberger B.

(6) A future prediction type artificial heart systemArtificial organsMarch 1, 1999Yambe T, Tanizuka N, Tanaka A, Yoshizawa M, Abe K, Takeda H, Tabayashi K, Nitta S.

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