Description
An LDH-A inhibitor (Ki = 8 µM); selective for LDH-A over GAPDH (Ki = >300 µM); increases oxygen consumption and the production of ROS, as well as induces cell death in P493-6 cells; reduces tumor volume in a P493-6 mouse xenograft model at 42 µg/animal, i.p.; reduces tumor weight in a BxPC-3 mouse xenograft model at 2 mg/kg