NSC59984 from MyBioSource.com

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NSC59984

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Description

NSC59984 induces mutant p53 protein degradation via MDM2 and the ubiquitin-proteasome pathway. The EC50 of NSC59984 in most cancer cells is significantly lower than those of normal cells, with EC50 of 8.38uM for p53-null HCT116 cells