Apremilast from MedChemExpress | Biocompare.com

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Apremilast

Description

Apremilast (CC-10004) is an orally available inhibitor of type-4 cyclic nucleotide phosphodiesterase (PDE-4) with an IC₅₀ of 74 nM. Apremilast inhibits TNF-α release by lipopolysaccharide (LPS) with an IC₅₀ of 104 nM

Product Specs
ItemApremilast
CompanyMedChemExpress
Price $61.00Supplier Page View Company Product Page
Catalog NumberHY-12085
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.91%
TypeChemical
Molecular Weight460.50
Molecule NameApremilast
FormulaC22H24N2O7S
Research AreaInflammation/Immunology

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(1) Determination of Apremilast in Rat Plasma by UPLC-MS-MS and Its Application to a Pharmacokinetic StudyJournal of chromatographic scienceSeptember 1, 2016Chen LG, Wang Z, Wang S, Li T, Pan Y, Lai X.

(2) Apremilast, a novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectorsArthritis research & therapySeptember 15, 2015Perez-Aso M, Montesinos MC, Mediero A, Wilder T, Schafer PH, Cronstein B.

(3) Research methods in sport and exercise psychology: quantitative and qualitative issuesJournal of sports sciencesOctober 1, 2001Biddle SJ, Markland D, Gilbourne D, Chatzisarantis NL, Sparkes AC.

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