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Protein Biochemistry
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SAR-20347
SAR-20347 from MedChemExpress
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Citations:
(3)
Supplier Page
Supplier Page from
MedChemExpress for
SAR-20347
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Description
SAR-20347 is an inhibitor of
TYK2
,
JAK1
,
JAK2
and
JAK3
with
IC
50
s of 0.6, 23, 26 and 41 nM, respectively
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
SAR-20347
Company
MedChemExpress
Price
$99.00
Supplier Page
View Company Product Page
Catalog Number
HY-100895
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Type
Chemical
Molecular Weight
444.84
Formula
C₂₁H₁₈ClFN₄O₄
Research Area
Cancer
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (3)
(1)
Activated T cell extracellular vesicle DNA transfer enhances antigen presentation and anti-tumor immunity
Cancer Cell
May 11, 2026
Mengying Hu, Di-Ao Liu, Inbal Wortzel, Paul Collier, Theodore M. Nelson, Jonathan Foox, Guojie Zhong, Gabriel Tobias, Tetsuhiko Asao, Linda Bojmar,
et al.
addition of PBS, 5 ng mL−1 of recombinant IFN-γ (
Biolegend
,
575302
), 2μM of
SAR-20347
(
MedChemExpress
,
HY-100895
),
mouse
ATEVs or NTEVs (containing 5 μg mL−1 of EVDNA), Baseline-ZERO DNase-pretreated ATEVs (containing
(2)
Virus-induced accumulation of intracellular bile acids activates the TGR5-β-arrestin-SRC axis to enable innate antiviral immunity
Cell research
March 1, 2019
Hu MM, He WR, Gao P, Yang Q, He K, Cao LB, Li S, Feng YQ, Shu HB.
METHODS Reagents, antibodies,
viruses
and cells The kinase
inhibitors
BMS-345541
(
HY-10518
),
SAR-20347
(
HY100895
),
MRT67307
(
HY-13018
),
INT-777
(
HY-15677
), LCA(
HYB0172
), CDCA(
HY-76847
), DCA(
HY-N0593
) and CA (
HY-N0324
) were
(3)
Inhibition of TYK2 and JAK1 ameliorates imiquimod-induced psoriasis-like dermatitis by inhibiting IL-22 and the IL-23/IL-17 axis
Journal of immunology (Baltimore, Md. : 1950)
October 1, 2014
Works MG, Yin F, Yin CC, Yiu Y, Shew K, Tran TT, Dunlap N, Lam J, Mitchell T, Reader J,
et al
.
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SAR-20347 from MedChemExpress
Supplier Page
View Company Product Page
$99.00
Product Specs
Company Info
Citations
Reviews
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