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Protein Biochemistry
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APY0201
APY0201 from MedChemExpress
Be the first to write a review!
Citations:
(4)
Supplier Page
Supplier Page from
MedChemExpress for
APY0201
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Description
APY0201 is a potent
PIKfyve
inhibitor, which inhibits the conversion of PtdIns3P to PtdIns(3,5)P
2
in the presence of in the presence of [
33
P]ATP with an
IC
50
of 5.2 nM. APY0201 also inhibits
IL-12/IL-23
production
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
APY0201
Company
MedChemExpress
Price
$145.00
Supplier Page
View Company Product Page
Catalog Number
HY-15982
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.42%
Type
Chemical
Molecular Weight
413.48
Formula
C₂₃H₂₃N₇O
Research Area
Inflammation/Immunology
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (4)
(1)
Concurrent Inhibition of the RAS-MAPK Pathway and PIKfyve is a Therapeutic Strategy for Pancreatic Cancer
Cancer Res
April 15, 2025
Jonathan M. DeLiberty, Mallory K. Roach, Clint A. Stalnecker, Ryan Robb, Elyse G. Schechter, Noah L. Pieper, Khalilah E. Taylor, Lily M. Pita, Runying Yang, Scott Bang,
et al.
specific
KRAS
inhibitors
(MRTX1133, G12Di; MRTX849, G12Ci) were purchased from
Selleckchem
.
APY0201
(
HY-15982
) was purchased from
MedChemExpress
. Chloroquine diphosphate (
C6628
) and polybrene (#TR-1003) was purchased
(2)
Concurrent Inhibition of the RAS-MAPK Pathway and PIKfyve Is a Therapeutic Strategy for Pancreatic Cancer
Cancer Research
April 15, 2025
Jonathan M. DeLiberty, Mallory K. Roach, Clint A. Stalnecker, Ryan Robb, Elyse G. Schechter, Noah L. Pieper, Khalilah E. Taylor, Lily M. Pita, Runying Yang, Scott Bang,
et al.
specific
KRAS
inhibitors
(MRTX1133, G12Di; MRTX849, G12Ci) were purchased from
Selleckchem
.
APY0201
(
HY-15982
) was purchased from
MedChemExpress
. Chloroquine diphosphate (
C6628
) and polybrene (#TR-1003) was purchased
(3)
Identification of PIKfyve kinase as a target in multiple myeloma
Haematologica
June 1, 2020
de Campos CB, Zhu YX, Sepetov N, Romanov S, Bruins LA, Shi CX, Stein CK, Petit JL, Polito AN, Sharik ME,
et al
.
dilution of drug concentration, starting at 40 μM, and incubated for 72 h with
APY0201
(
MedChemExpress
,
HY-15982
, Monmouth Junction, NJ, USA), apilimod (
Santa Cruz Biotechnology
, sc-480051, Dallas, TX, USA), and
YM201636
(4)
Structure-activity relationship study, target identification, and pharmacological characterization of a small molecular IL-12/23 inhibitor, APY0201
Bioorganic & medicinal chemistry
June 1, 2014
Hayakawa N, Noguchi M, Takeshita S, Eviryanti A, Seki Y, Nishio H, Yokoyama R, Noguchi M, Shuto M, Shima Y,
et al
.
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APY0201 from MedChemExpress
Supplier Page
View Company Product Page
$145.00
Product Specs
Company Info
Citations
Reviews
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