DMH-1 from MedChemExpress

Product Specs
ItemDMH-1
CompanyMedChemExpress
Price $119.00Supplier Page View Company Product Page
Catalog NumberHY-12273
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.95%
TypeChemical
Molecular Weight380.44
FormulaC₂₄H₂₀N₄O
Research AreaCancer

Add to Compare List

MedChemExpress

1 Deer Park Drive, Suite F

MONMOUTH JUNCTION, NJ 08852

United States

Phone: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910

Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com

Company Profile

Website: medchemexpress.com

(1) CRISPR/Cas9-mediated B2m knockout paves the way for allogeneic basal cell transplantationRespiratory ResearchFebruary 28, 2026Huanjie Chen, Weizhan Luo, Ning Ma, Shiyue LiChina) supplemented with Y‐27,632 (#HY‐10182, MCE, USA), CHIR‐99,021 (#HY‐10182, MCE, USA), D‐MH1 (#HY‐12273, MCE, USA), and A‐8301 (#HY‐10432, MCE, USA). Mesenchymal cells were removed through magnetic separation

(2) Rapid and Simplified Induction of Spinal Motor Neurons From Human Induced Pluripotent Stem CellsBio ProtocOctober 20, 2025YaoYao Chen, Fan Yang, Timothy O'Brien, Sanbing Shen, Meimei YangHY-10182) 17. SB-431542 (MedChemExpress, catalog number: HY-10431) 18. DMH-1 (MedChemExpress, catalog number: HY-12273) 19. Retinoic acid (MedChemExpress, catalog number: HY-14649) 20. Purmorphamine (MedChemExpress, catalog

(3) Rapid and Simplified Induction of Spinal Motor Neurons From Human Induced Pluripotent Stem CellsBIO-PROTOCOLOctober 20, 2025YaoYao Chen, Fan Yang, Timothy O'Brien, Sanbing Shen, Meimei YangHY-10182) 17. SB-431542 (MedChemExpress, catalog number: HY-10431) 18. DMH-1 (MedChemExpress, catalog number: HY-12273) 19. Retinoic acid (MedChemExpress, catalog number: HY-14649) 20. Purmorphamine (MedChemExpress, catalog

(4) Delaying pyroptosis with an AI-screened gasdermin D pore blocker mitigates inflammatory responseNature immunologyOctober 1, 2025Sun J, Yang J, Tao J, Yang Y, Wang R, Zhang H, Liu W, Zhao S, Shao R, He Y, et al.SB431542 (HY-10431, MCE), 3 μM CHIR99021 (HY-10182, MCE), 1 μM BIRB796 (HY-10320, MCE), 1 μM DMH-1 (HY-12273, MCE), 10 μM Y-27632 (HY-10071, MCE), 50 ng ml−1 human EGF (236-EG-200, R&D Systems), 10 ng ml−1 human

(5) Polyethyleneimine facilitates the growth and electrophysiological characterization of iPSC-derived motor neuronsScientific ReportsOctober 30, 2024Meimei Yang, Daofeng You, Gang Liu, Yin Lu, Guangming Yang, Timothy O’Brien, David C. Henshall, Orla Hardiman, Li Cai, Min Liu, et al.replenished with NIM medium and 3 μM CHIR99021 (HY-10182, MCE), 2 μM SB (HY-10431, MCE), and 2 μM DMH1 (HY-12273, MCE) were freshly added. Cells were subsequently split 1:3 onto Geltrex-coated plates in NIM containing

(6) Genetic Screening of Haploid Neural Stem Cells Reveals that Nfkbia and Atp2b4 are Key Regulators of Oxidative Stress in Neural PrecursorsAdvanced ScienceAugust 1, 2024Shaochen Nie, Wenhao Zhang, Xin Jin, Xiaoyan Li, Shengyi Sun, Yiding Zhao, Qingshen Jia, Luyuan Li, Yan Liu, Dayong Liu, et al.24 h. Then the Ndiff medium was supplemented with 2 µm SB‐431542 (MCE, HY10431, China) and DMH1(MCE, HY12273, USA) for 7 days, with medium half‐changed daily. After 7 days of culture, the aggregates were transferred

(7) NAT10‐mediated ac4C modification promotes ectoderm differentiation of human embryonic stem cells via acetylating NR2F1 mRNACell ProliferationApril 1, 2024Junbang Ge, Zhaoxia Wang, Ji Wusupplement (12587010; Gibco), 3 μM CHIR99021 (SML1046; Sigma), 1% GlutaMax™ (35050061; Gibco), 2 μM DMH1(HY‐12273; MCE) and 2 μM SB431542 (HY‐10431; MCE) and it took 6 days to culture the cells. Differentiation of

(8) A novel protocol to derive cervical motor neurons from induced pluripotent stem cells for amyotrophic lateral sclerosisStem cell reportsSeptember 12, 2023Yang M, Liu M, Sánchez YF, Avazzadeh S, Quinlan LR, Liu G, Lu Y, Yang G, O''Brien T, Henshall DC, et al.renewed every other day with fresh 3 μM CHIR (HY-10182, MCE), 2 μM SB (HY-10431, MCE), and 2 μM DMH1 (HY-12273, MCE) for 6 days. Cells were then split 1:3 onto Geltrex-coated plates in NIM with 1 μM CHIR, 2 μM SB,

(9) CoQ10 enhances the efficacy of airway basal stem cell transplantation on bleomycin-induced idiopathic pulmonary fibrosis in miceRespiratory researchFebruary 26, 2022Liu H, Liu S, Jiang J, Zhang Y, Luo Y, Zhao J, Xu J, Xie Y, Liao W, Wang W, et al.ROCK inhibitor Y-27632 (Sigma, Cat. SCM075), 1 μM A-83-01 (Sigma, Cat.SML0788), 1 μM DMH-1 (MedChemExpress, Cat. HY-12273), 1 μM CHIR99021 (Sigma, Cat.SML1046), and 1× Antibiotic–Antimycotic medium (ThermoFisher, Cat. 15240062)

(10) Small molecule inhibitor of the bone morphogenetic protein pathway DMH1 reduces ovarian cancer cell growthCancer lettersNovember 1, 2015Hover LD, Young CD, Bhola NE, Wilson AJ, Khabele D, Hong CC, Moses HL, Owens P.

(11) DMH1 (4-[6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline) inhibits chemotherapeutic drug-induced autophagyActa pharmaceutica Sinica. BJuly 1, 2015Sheng Y, Sun B, Xie X, Li N, Dong D.

(12) DMH1, a small molecule inhibitor of BMP type i receptors, suppresses growth and invasion of lung cancerPloS oneJanuary 1, 2014Hao J, Lee R, Chang A, Fan J, Labib C, Parsa C, Orlando R, Andresen B, Huang Y.

(13) Synthesis and structure-activity relationships of a novel and selective bone morphogenetic protein receptor (BMP) inhibitor derived from the pyrazolo[1.5-a]pyrimidine scaffold of dorsomorphin: the discovery of ML347 as an ALK2 versus ALK3 selective MLPCN probeBioorganic & medicinal chemistry lettersJune 1, 2013Engers DW, Frist AY, Lindsley CW, Hong CC, Hopkins CR.

(14) DMH1, a highly selective small molecule BMP inhibitor promotes neurogenesis of hiPSCs: comparison of PAX6 and SOX1 expression during neural inductionACS chemical neuroscienceJune 20, 2012Neely MD, Litt MJ, Tidball AM, Li GG, Aboud AA, Hopkins CR, Chamberlin R, Hong CC, Ess KC, Bowman AB.

Be the First to Write a Review!

Description

MedChemExpress

Citations (14)

Reviews

DMH-1 from MedChemExpress

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map