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Protein Biochemistry
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FMK
FMK from MedChemExpress
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Citations:
(6)
Supplier Page
Supplier Page from
MedChemExpress for
FMK
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Description
FMK is a an irreversible
RSK2
kinase inhibitor, that covalently modifies the C-terminal kinase domain of RSK
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
FMK
Company
MedChemExpress
Price
$249.00
Supplier Page
View Company Product Page
Catalog Number
HY-52101A
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.83%
Type
Chemical
Molecular Weight
342.37
Molecule Name
FMK
Formula
C18H19FN4O2
Research Area
Cancer
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (6)
(1)
EGFR-phosphorylated GDH1 harmonizes with RSK2 to drive CREB activation and tumor metastasis in EGFR-activated lung cancer
Cell reports
December 13, 2022
Kang J, Chun J, Hwang JS, Pan C, Li J, Boese AC, Young I, Malin CM, Kang Y, Gibbons DL,
et al
.
189197-69-1 "
2,4-Diamino-6-hydroxypyrimidine
, DAHP",Selleckchem,Cat#S3688; CAS: 56-06-4 fmk,
MedChemExpress
,Cat#
HY-52101A
; CAS: 821794-92-7
BI-D1870
,
Selleckchem
,Cat#
S2843
; CAS: 501437-28-1
LJI308
,
Selleckchem
,Cat#
S7871
; CAS:
(2)
The selectivity of protein kinase inhibitors: a further update
The Biochemical journal
December 15, 2007
Bain J, Plater L, Elliott M, Shpiro N, Hastie CJ, McLauchlan H, Klevernic I, Arthur JS, Alessi DR, Cohen P.
(3)
FGFR3 activates RSK2 to mediate hematopoietic transformation through tyrosine phosphorylation of RSK2 and activation of the MEK/ERK pathway
Cancer cell
September 1, 2007
Kang S, Dong S, Gu TL, Guo A, Cohen MS, Lonial S, Khoury HJ, Fabbro D, Gilliland DG, Bergsagel PL,
et al
.
(4)
Evidence for direct regulation of myocardial Na+/H+ exchanger isoform 1 phosphorylation and activity by 90-kDa ribosomal S6 kinase (RSK): effects of the novel and specific RSK inhibitor fmk on responses to alpha1-adrenergic stimulation
Molecular pharmacology
March 1, 2007
Cuello F, Snabaitis AK, Cohen MS, Taunton J, Avkiran M.
(5)
[Reflex algodystrophy of the lower limbs during pregnancy]
Revue du rhumatisme et des maladies osteo-articulaires
February 1, 1978
Cayla J, Chaouat D, Rondier J, Guérin K, Frugier JC.
(6)
ADAM Sheddase Activity Promotes the Detachment of Small Extracellular Vesicles From the Plasma Membrane
Journal of extracellular vesicles
January 1, 0001
"Bizingre C, Arellano-Anaya Z, Picard F, Pietri M, Baudry A, Roussel F, Bianchi C, Alleaume-Butaux A, Ardila-Osorio H, Romao M,
et al
."
SL0101 (
TOCRIS Bioscience
,
2250
) and the C‐terminal kinase domain of RSK2
inhibitor
FMK
(
MedChemExpress
,
HY‐52101A
) were prepared as 10 mM stock solution dissolved in 0.22 µM filtered water for
TAPI‐2
or 90%
dimethyl sulfoxide (DMSO
<<
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FMK from MedChemExpress
Supplier Page
View Company Product Page
$249.00
Product Specs
Company Info
Citations
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