Pemetrexed from MedChemExpress

Product Specs
ItemPemetrexed
CompanyMedChemExpress
Price $66.00Supplier Page View Company Product Page
Catalog NumberHY-10820
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.95%
TypeChemical
Molecular Weight427.41
Molecule NamePemetrexed
FormulaC20H21N5O6
Research AreaCancer

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(1) Concurrent PIK3CA mutant promotes cachexia through inflammatory signaling in EGFR mutant lung cancerNature CommunicationsDecember 16, 2025Meiting Yue, Zhen Qin, Shijie Tang, Xinlei Cai, Yikai Zhao, Chen Yang, Liang Chen, Luonan Chen, Hongbin JiHY-15772) was prepared in a solution containing 5% DMSO, 40% PEG300, 5% Tween-80, and 50% saline. PEM (MCE, HY-10820) or aspirin (MCE, HY-14654) was prepared in a solution containing 10% DMSO, 40% PEG300, and 50% saline.

(2) The lysosomal cysteine protease cathepsin L promotes stemness and multidrug resistance of non-small cell lung cancer by targeting HGF activatorMolecular and Cellular BiochemistryNovember 3, 2025Hui Shi, Jianyu Xu, Juan Wu, Sha Hu, Xi Chen, Qianfang Hu, Qian Liu, Yanxia Yu, Xinyuan Ding, Wenjuan WangHY-B0015, MedChemExpress, Shanghai, China); Docetaxel (DTX, HY-B0011, MedChemExpress); Pemetrexed (PEM, HY-10820, MedChemExpress); Gemcitabine (GEM, HY-17026, MedChemExpress); Carboplatin (CBP, HY-17393, MedChemExpress);

(3) FL496, an FL118-derived small molecule, induces growth inhibition, senescence, and apoptosis of malignant pleural mesothelioma (MPM) cells, and exhibits anti-MPM tumor efficacy strikingly superior to the pemetrexed-cisplatin combinationJ Exp Clin Cancer ResOctober 21, 2025Ieman A. M. Aljahdali, Xiang Ling, Wenjie Wu, Wenchao Wang, Dan Li, Renyuan Zhang, Emma Zhang, Aimee Stablewski, Rami Azrak, Qingyong Li, et al.(active irinotecan metabolite) was purchased from Selleckchem (Houston, TX, USA). Pemetrexed disodium (HY-10820 A) was purchased from MedChemExpress (MCE, Monmouth Junction, NJ, USA). Cisplatin (232120) was purchased

(4) Using patient-derived organoids to predict locally advanced or metastatic lung cancer tumor response: A real-world studyCell Reports MedicineFebruary 21, 2023Han-Min Wang, Chan-Yuan Zhang, Kai-Cheng Peng, Ze-Xin Chen, Jun-Wei Su, Yu-Fa Li, Wen-Feng Li, Qing-Yun Gao, Shi-Ling Zhang, Yu-Qing Chen, et al.HY-B0011 Paclitaxel,MCE,Cat# HY-B0015 Gemcitabine,MCE,Cat# HY-17026 Etoposide,MCE,Cat# HY-13629 Pemetrexed,MCE,Cat# HY-10820 Cisplatin,MCE,Cat# HY-17394 Carboplatin,MCE,Cat# HY-17393 Irinotecan,MCE,Cat# HY-16562 ,, Experimental models

(5) Targeting mitochondrial one-carbon enzyme MTHFD2 together with pemetrexed confers therapeutic advantages in lung adenocarcinomaCell death discoveryJuly 5, 2022Mo J, Gao Z, Zheng L, Yan M, Xue M, Xu J, Bao Y, Wu J.at 37 °C with 5% CO2. A specific MTHFD2 inhibitor DS18561882 (HY-130251) and chemo-drug pemetrexed (HY-10820) were purchased from MedChemExpress (MCE, NJ, USA). To determine the half maximal inhibitory concentration

(6) Serine hydroxymethyltransferase 2 expression promotes tumorigenesis in rhabdomyosarcoma with 12q13-q14 amplificationThe Journal of clinical investigationAugust 2, 2021Nguyen TH, Vemu PL, Hoy GE, Boudjadi S, Chatterjee B, Shern JF, Khan J, Sun W, Barr FG.in assay medium with control (DMSO) or 2-fold serial dilutions of SHIN1 (AOB36697, AOBIOUS) or PEM (HY-10820, MedChemExpress). DMSO was adjusted to 0.064% as the final concentration in all wells. The assay was

(7) Synergistic antitumor effects of regulatory T cell blockade combined with pemetrexed in murine malignant mesotheliomaJournal of immunology (Baltimore, Md. : 1950)July 15, 2010Anraku M, Tagawa T, Wu L, Yun Z, Keshavjee S, Zhang L, Johnston MR, de Perrot M.

(8) LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymesCancer researchMarch 15, 1997Shih C, Chen VJ, Gossett LS, Gates SB, MacKellar WC, Habeck LL, Shackelford KA, Mendelsohn LG, Soose DJ, Patel VF, et al.

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Pemetrexed from MedChemExpress

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Pemetrexed from MedChemExpress

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