Hydroxy-Dynasore from MedChemExpress

Product Specs
ItemHydroxy-Dynasore
CompanyMedChemExpress
Price $64.00Supplier Page View Company Product Page
Catalog NumberHY-13863
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
TypeChemical
Molecular Weight338.31
FormulaC₁₈H₁₄N₂O₅
Research AreaNeurological Disease
Purity99.11%

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(1) Fully human anti-B7-H4 antibody induces lysosome-dependent ferroptosis to reverse primary resistance to PD-1 blockadeJournal for immunotherapy of cancerJanuary 12, 2026Zhang R, Wang Y, Wu Y, Zheng B, Cao Q, Chen Y, Cao Z, Zhu Y, Zhou L, Zhang Q.(#D9542, Merck) for indicated durations. To block endocytosis, cells were pretreated with 30 µM Dyngo 4a (#HY-13863, MedChemExpress). Internalization in 293T-mH4-GFP cells was observed after 24 hours. For lysosomal colocalization

(2) Antibody-induced internalization and degradation of PLA2R amplifies CD4+ T cell activationTheranosticsJanuary 1, 2026Yuning Liu, Yinyin Li, Hui Zhou, Jieli Yu, Pei Deng, Weiwei Xu, Bingqian Pan, Lei Zhang, Hong Zhou, Jing Zhang, et al.were purchased from Selleck Chemicals; Cocktail (HY-K0010), Nocodazole(HY-13520, 10 μM), Dynasore (HY-13863, 90 μM), Cytochalasin D (HY-N6682, 30 μM) were obtained from MedChemExpress. CD19 magnetic beads (130-050-301)

(3) Endocytotic Albumin Uptake Pathways in Human Adipose Stem Cells and Connection to Intracellular Calcium Oscillations and the Neonatal Fc receptor (FcRn)Cells Tissues OrgansApril 16, 2025Md Tanvir Morshed, Anne Bernhardt, Maria Wartenberg, Heinrich SauerDMSO, cat. No. Cay11330-1, Cayman Chemical, Ann Arbor, MI, USA), Dyngo-4a (10 mm in DMSO, cat. No. HY-13863, MedChemExpress), ethylisopropylamiloride (EIPA) (10 mm in DMSO, cat. No. 14406, Cayman Chemical), FcRn

(4) MSC-derived exosomes protect auditory hair cells from neomycin-induced damage via autophagy regulationBiological ResearchJanuary 13, 2024Huan Liu, Huijuan Kuang, Yiru Wang, Lili Bao, Wanxin Cao, Lu Yu, Meihao Qi, Renfeng Wang, Xiaoshan Yang, Qingyuan Ye, et al.(30 μg/ml for 24 h) or the same amount of PBS. Chloroquine (HY-17589A), 3-MA (HY-19312), Dynasore (HY-13863), and Cytochalasin D (HY-N6682) were purchased from MCE (USA). Western blot Cells and tissue samples

(5) Ubiquitin ligase RNF125 targets PD-L1 for ubiquitination and degradationFrontiers in oncologyJanuary 1, 2022Wei M, Mo Y, Liu J, Zhai J, Li H, Xu Y, Peng Y, Tang Z, Wei T, Yang X, et al.(Shanghai, China). Pitstop-2 (ab120687) was purchased from Abcam (Illinois, USA). Hydroxy-Dynasore (HY-13863) was purchased from MedChemExpress (New Jersey, USA). CellTiter-Glo® Luminescent Cell Viability Assay

(6) Building a better dynasore: the dyngo compounds potently inhibit dynamin and endocytosisTraffic (Copenhagen, Denmark)December 1, 2013McCluskey A, Daniel JA, Hadzic G, Chau N, Clayton EL, Mariana A, Whiting A, Gorgani NN, Lloyd J, Quan A, et al.

(7) Dynamin inhibition blocks botulinum neurotoxin type A endocytosis in neurons and delays botulismThe Journal of biological chemistryOctober 14, 2011Harper CB, Martin S, Nguyen TH, Daniels SJ, Lavidis NA, Popoff MR, Hadzic G, Mariana A, Chau N, McCluskey A, et al.

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Hydroxy-Dynasore from MedChemExpress

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Hydroxy-Dynasore from MedChemExpress

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