Milrinone from MedChemExpress

Product Specs
ItemMilrinone
CompanyMedChemExpress
Price $73.00Supplier Page View Company Product Page
Catalog NumberHY-14252
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.80%
TypeChemical
Molecular Weight211.22
Molecule NameMilrinone
FormulaC12H9N3O
Research AreaCardiovascular Disease

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(1) The mechanisms of DEPDC7-mediated actin cap establishment and meiosis progression in oocytesEMBO ReportsJune 22, 2026Jian Mu, Siyuan Xie, Lin Zhao, Yang Zeng, Hao Gu, Zhiqi Pan, Ran Yu, Zhihua Zhang, Tianyu Wu, Weijie Wang, et al.,Thermo Fisher,A22282 Hoechst 33342,MedChemExpress,HY-15559 M2 medium,Aibei Biotechnology,M1205 Milrinone,MCE,HY-14252 Hyaluronidase,Aibei Biotechnology,M2215 Fetal bovine serum (FBS),Gibco,A5256701 Bovine serum albumin (BSA

(2) Loss of DLGAP5 impairs human and mouse oocyte maturation via disrupting the PI3K-AKT signaling axisJournal of Ovarian ResearchMay 13, 2026Meng Wang, Juepu Zhou, Youzhu Li, Zhou Li, Rui Long, Xiangfei Wang, Ruolin Mao, Lei Xu, Lei Cai, Bing Han, et al.endogenous DLGAP5 knockdown in a G1-plus medium (Vitrolife, Sweden) supplemented with milrinone (Cat: HY-14252, MCE, Shanghai, China) in a time-lapse incubator with 6% CO2 and 5% O2 at 37 ℃. After release, GV oocytes

(3) Maternal obesity disrupts epigenetic reprogramming via peroxisomal-dependent phospholipid-methyl uncoupling during zygotic genome activationNature CommunicationsMarch 18, 2026Xiao-Guohui Zhang, Lin-Li Yang, Xie Feng, Yu-Wei Zhang, Lei Guo, Sun-Xing Huang, Tie-Gang Meng, Pei-Ying Li, Lei-Ning Chen, Rui-Bao Su, et al.The GV oocyte were collected by M2 medium (Sigma Aldrich, M7167) containing 2.5 μM Milrinone (MCE, HY-14252) to inhibit spontaneous GVBD. After microinjection, oocytes were washed and cultured in M2 medium at

(4) hnRNPM cooperates with BCAS2 to modulate alternative splicing during oocyte developmentNature CommunicationsFebruary 12, 2026Shumin Zhou, Dalin Liu, Shiming Gan, Ziqi Yu, Ruibao Su, Hao Zhou, Jiaqi Zhang, Haoran Xu, Yifan Zhao, Hua Zhang, et al.pipette. GV oocytes were harvested in M2 medium (Sigma, M7167) supplemented with 2.5 μM milrinone (MCE, HY-14252). Only full-grown GV oocytes were cultured in M16 medium (Sigma, M7292) and covered with mineral oil

(5) IRE1α RNase activity is critical for early embryo development by degrading maternal transcriptsNucleic Acids ResJune 18, 2025Chao Li, Yong-Peng Tan, Di Gao, Ruibao Su, Ke Xu, Shu-Chen Liu, Xu-Feng Li, You-Hui Lu, Li-Tao Yi, Guang Wang, et al.vesicle (GV) oocytes were collected from ovaries using M2 medium containing 2.5 μM milrinone (MCE, HY-14252), and then washed five times with milrinone-free M2 medium and cultured in M2 medium at 37°C in a 5%

(6) CDK1 mediates the metabolic regulation of DNA double-strand break repair in metaphase II oocytesBMC BiolFebruary 6, 2025Tian-Jin Xia, Feng-Yun Xie, Juan Chen, Xiao-Guohui Zhang, Sen Li, Qing-Yuan Sun, Qin Zhang, Shen Yin, Xiang-Hong Ou, Jun-Yu Masurrounding cumulus cells by a mouth pipette. To block GV-stage oocytes from GVBD, 2.5 μM milrinone (MCE, HY-14252) was added to M2 medium for oocyte manipulation. To isolate in vivo oocytes at different maturation

(7) PATL2 mutations affect human oocyte maternal mRNA homeostasis and protein interactions in cell cycle regulationCell & bioscienceDecember 31, 2024Zhang YL, Hu Z, Jiang H, Jin J, Zhou Y, Lai M, Ren P, Liu S, Zhang YY, Rong Y, et al.(Sigma, M5910). For microinjection, the GV oocytes were cultured in M2 medium with 2.5 µM milrinone (HY14252, MCE). The GV oocytes were matured in vitro to MII stage in M2 medium for 14 h. In vitro mRNA transcription

(8) Dynamic of centromere associated RNAs and the centromere loading of DNA repair proteins in growing oocytesFrontiers in GeneticsMarch 24, 2023Lin-Li Yang, Yan-Chu Li, Tian-Jin Xia, Sen Li, Xie Feng, Chao Li, Feng-Yun Xie, Xiang-Hong Ou, Jun-Yu Maovarian tissue fragments were dispersed by M2 medium (Sigma-Aldrich, M7167) with 2.5 μM Milrinone (MCE, HY-14252). The denuded oocytes were picked out with mouth pipette. To isolate the NSN oocytes from preantral

(9) Aristolochic acid I exposure decreases oocyte qualityFrontiers in Cell and Developmental BiologyAugust 11, 2022Weidong Li, Jiaming Zhang, Xiaoxia Yu, Fei Meng, Ju Huang, Liangran Zhang, Shunxin Wangcollected in the M2 medium (M7167, Sigma-Aldrich, United States) supplemented with 2.5 μM milrinone (HY-14252, MCE, United States). Collected ovaries were then gently and repeatedly punctured with a 1 ml syringe

(10) Double-strand breaks induce short-scale DNA replication and damage amplification in the fully grown mouse oocytesGeneticsJune 24, 2021Ma JY, Feng X, Xie FY, Li S, Chen LN, Luo SM, Yin S, Ou XH.resumption, all of the manipulations were in the M2 medium (Sigma, M7167) with 2.5 μM Milrinone (MCE, HY-14252). Treatment of oocytes by molecule compounds DSBs in oocytes were introduced with Bleomycin at different

(11) ADAMTS1 and HSPG2 mRNA levels in cumulus cells are related to human oocyte quality and controlled ovarian hyperstimulation outcomesJournal of Assisted Reproduction and GeneticsMarch 1, 2020Yerong Ma, Jiamin Jin, Xiaomei Tong, Weijie Yang, Peipei Ren, Yongdong Dai, Yibin Pan, YinLi Zhang, Songying ZhangIU PMSG treatment for 48 h. IVM medium (Easy Check, China, M2115) with 2.5 μM milrinone (MCE, USA, HY-14252) was used to inhibit CCs expansion during collection and culture with siRNA. Prior to COCs collection,

(12) Cruciform DNA in mouse growing oocytes: Its dynamics and its relationship with DNA transcriptionPloS oneJanuary 1, 2020Feng X, Xie FY, Ou XH, Ma JY.in this study were under the oocyte manipulation media M2 (Sigma, M7167) with 2.5 μM milrinone (MCE, HY-14252) to block the oocytes from meiosis resumption. To isolate the large antral follicle oocytes, ovaries

(13) Milrinone attenuates thromboxane receptor-mediated hyperresponsiveness in hypoxic pulmonary arterial myocytesBritish journal of pharmacologyJuly 1, 2011Santhosh KT, Elkhateeb O, Nolette N, Outbih O, Halayko AJ, Dakshinamurti S.

(14) Inhalation of the phosphodiesterase-3 inhibitor milrinone attenuates pulmonary hypertension in a rat model of congestive heart failureAnesthesiologyJanuary 1, 2007Hentschel T, Yin N, Riad A, Habbazettl H, Weimann J, Koster A, Tschope C, Kuppe H, Kuebler WM.

(15) Effects of milrinone on left ventricular end-systolic pressure-volume relationship of rat hearts in situClinical and experimental pharmacology & physiologySeptember 1, 2001Kishi T, Nakahashi K, Ito H, Taniguchi S, Takaki M.

(16) Effect of milrinone on small mesenteric artery vasoconstriction: role of K(+) channelsThe American journal of physiologyJuly 1, 1999Taylor MS, Benoit JN.

(17) Tyrosine hydroxylase and dopamine-beta-hydroxylase: distribution in discrete areas of the rat limbic systemBrain researchApril 9, 1976Saavedra JM, Zivin J.

(18) RSPO2 Coordinates with GDF9:BMP15 Heterodimers to Promote Granulosa Cell and Oocyte Development in Mice"Advanced science (Weinheim, Baden-Wurttemberg, Germany)"January 1, 0001"Wang Y, Li H, You L, Wang S, Bie J, Su Z, Shi L, Su YQ."ROS labeling) or 20 min (JC‐1 staining) at 37 °C in a humidified atmosphere of 5% CO₂. Milrinone (Cat#HY‐14252/CS‐1367, MedChemExpress, Monmouth Junction, New Jersey, USA) was added into the GV‐stage oocyte culture

(19) The E3 ubiquitin ligase adaptor KLHL8 targets ZAR1 to regulate maternal mRNA degradation in oocytesEMBO reportsJanuary 1, 0001"Fan H, Liu R, Yu R, Chen B, Li Q, Mu J, Wang W, Wu T, He L, Wang L, et al."medium,Aibei Biotechnology,M1205 PMSG,Aibei Biotechnology,M2620 hCG,Aibei Biotechnology,M2520 Milrinone,MCE,HY-14252 Hyaluronidase,Aibei Biotechnology,M2215 DMEM high glucose,meilun,MA0212 Fetal bovine serum (FBS),Gibco,A5256701 Penicillin–streptomycin,meilun,MA0110 0.25%

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Milrinone from MedChemExpress

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Milrinone from MedChemExpress

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