SHP836 from MedChemExpress | Biocompare.com

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SHP836

Description

SHP836 is a SHP2 allosteric inhibitor, with an IC₅₀ of 12 µM for the full length SHP2

Product Specs
ItemSHP836
CompanyMedChemExpress
Price $330.00Supplier Page View Company Product Page
Catalog NumberHY-121879
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.39%
TypeChemical
Molecular Weight352.26
FormulaC₁₆H₁₉Cl₂N₅
Research AreaCancer

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(1) Structure based design of selective SHP2 inhibitors by De novo design, synthesis and biological evaluationJournal of computer-aided molecular designAugust 1, 2019Liu WS, Jin WY, Zhou L, Lu XH, Li WY, Ma Y, Wang RL.

(2) Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase InhibitorJournal of medicinal chemistrySeptember 8, 2016Garcia Fortanet J, Chen CH, Chen YN, Chen Z, Deng Z, Firestone B, Fekkes P, Fodor M, Fortin PD, Fridrich C, et al.

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