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Protein Biochemistry
Chemicals and Reagents
PI-273
PI-273 from MedChemExpress
Be the first to write a review!
Citations:
(5)
Supplier Page
Supplier Page from
MedChemExpress for
PI-273
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Description
PI-273 is a first reversibly and specific
phosphatidylinositol 4-kinase (PI4KIIα)
inhibitor with an
IC
50
of 0.47 µM. PI-273 can inhibit breast cancer cell proliferation, block the cell cycle and induce cell
apoptosis
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
PI-273
Company
MedChemExpress
Price
$336.00
Supplier Page
View Company Product Page
Catalog Number
HY-103489
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
98.47%
Type
Chemical
Molecular Weight
381.9
Formula
C₁₆H₁₆ClN₃O₂S₂
Research Area
Cancer
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (5)
(1)
Dynamic assessment of PI4P metabolism using split GFP based sensors
Sci Rep
August 21, 2025
Samantha K. A. Manuel, Erika Bilenka, Monica Gupta, Vincent T. Moy, Ralf Landgraf
30310
), IN10 (PI4KIIIbeta-IN10;
MedChemExpress
HY-100198
) or PI273 (PI4KIIα
inhibitor
;
MedChemExpress
HY-103489
) at the indicated concentrations. Plasmids and creation of stable lines
Transfections
were performed
(2)
A phosphoinositide switch mediates exocyst recruitment to multivesicular endosomes for exosome secretion
Nature Communications
October 28, 2023
Di-Ao Liu, Kai Tao, Bin Wu, Ziyan Yu, Malwina Szczepaniak, Matthew Rames, Changsong Yang, Tatyana Svitkina, Yueyao Zhu, Fengyuan Xu,
et al.
removed). Antibodies and reagents Antibody information is included in Supplementary Table 1.
PI-273
(
HY-103489
) was purchased from
MedChemExpress
. Endosidine-2 (ES2) was purchased from Sigma (1839524-44-5). from
(3)
EMT-activated secretory and endocytic vesicular trafficking programs underlie a vulnerability to PI4K2A antagonism in lung cancer
The Journal of clinical investigation
April 3, 2023
Tan X, Xiao GY, Wang S, Shi L, Zhao Y, Liu X, Yu J, Russell WK, Creighton CJ, Kurie JM.
(
ab92964
) from
Abcam
; recombinant Gas6 (885-GSB) and
SPP1
(
1433-OP-050
) proteins from
R&D Systems
;
PI-273
(
HY-103489
) from
MedChemExpress
;
NC03
(AOB17420) from Aobious; and miRNA mimics (HMI0508, HMI0275, and HMI0280)
(4)
PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KIIα, Inhibits the Growth of Breast Cancer Cells
Cancer research
November 15, 2017
Li J, Gao Z, Zhao D, Zhang L, Qiao X, Zhao Y, Ding H, Zhang P, Lu J, Liu J,
et al
.
(5)
Results for 79 patients with neuroblastoma detected through mass screening at 6 months of age in a single institute
Pediatrics international : official journal of the Japan Pediatric Society
December 1, 2006
Nishio N, Mimaya J, Nara T, Takashima Y, Horikoshi Y, Urushihara N, Hasegawa S, Aoki K, Hamasaki M.
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PI-273 from MedChemExpress
Supplier Page
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$336.00
Product Specs
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