Anisomycin from MedChemExpress

Product Specs
ItemAnisomycin
CompanyMedChemExpress
Price $73.00Supplier Page View Company Product Page
Catalog NumberHY-18982
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.82%
TypeChemical
Molecular Weight265.31
FormulaC₁₄H₁₉NO₄
Research AreaInfection; Cancer

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(1) Ouabain Relieves Sleep Deprivation-Induced Anxiety-Like Behavior in Mice by Suppressing Hippocampal Neuroinflammation and Oxidative StressBrain BehavJuly 24, 2026Hanxiao Zhu, Wei Wangpurity; CAS 11018‐89‐6; Sigma, St. Louis, USA), SU6656 (HY‐B0789; MedChemExpress, USA), anisomycin (HY‐18982; MedChemExpress), and TNF‐α (HY‐P1860; MedChemExpress) were dissolved in DMSO and then diluted with

(2) Learning Shapes the Energy Cost of Neural TasksbioRxivJuly 2, 2026Kaili Xue, Farid Rezayat, Tianbo Qi, Leyao Shen, Bohan Zhao, Xun Huang, Jonathan S. Marvin, Li Ye#ab120003), tetrodotoxin (TTX; 2 ng/site; Tocris, #1069), and anisomycin (25 μg/site; MedChemExpress, HY-18982). Histology and immunohistochemistry Mice were deeply anesthetized with isoflurane and transcardially

(3) Single-granule profiling reveals that RNP granule pH marks cellular translationiScienceJune 19, 2026Yue Zhang, Shining Wu, Yifeng He, Xuhan Xia, Jinchao Wei, Shijia Wu, Ruijie DengHoechst 33342,Solarbio,Cat# IH0070 H2O2,Macklin,Cat# H792077 Sorbitol,MCE,Cat# HY-B0400B Anisomycin,MCE,Cat# HY-18982 Myrtenol,OriLeaf,Cat# T78057 Curcumin,Adamas-beta,Cat# 01076873 Oridonin,OriLeaf,Cat# B20310 C12FDG,MCE,Cat#

(4) Metabolomic profiling delineates the role of adenosine in oocyte quality and embryonic developmentCell Death & DiseaseJune 9, 2026Jihong Yang, Hui Wang, Yangbai Li, Xinyue Zhang, Ting Feng, Suying Li, Yao Chen, Yuntian Xu, Ruizhi Feng, Minjian Chen, et al.gene reversal group was supplemented with individual treatment with 100 nM anisomycin (MedChemExpress, HY-18982, purity 99.82%) [84], 500 nM Ro-3306 (MedChemExpress, HY-12529, purity 99.57%) [85] or 5 nM proTAME

(5) Echinocystic Acid Antagonizes Post-Stroke Depression in Mice by Suppressing the JNK/NF-κB Signaling PathwayNeuropsychiatr Dis TreatJune 5, 2026Dandan Wang, Wei Li, Xuan Zhang, Kaiqi Zhu, Yuzhen Wang, Yaozhuo Cai, Hao Chen, Xueli Cai, Jingping Sun(510-30-5, Nanjing Spring & Autumn Biological Engineering Co., Ltd, China) and AN (0.1 mg/kg, i.p.) (HY-18982, MCE, USA). The concentrations of EA and AN were determined based on previously described studies.23,24

(6) ARAF regulates malignant progression of bladder cancer through the p38MAPK pathwayOpen Med (Wars)May 26, 2026Xian Zhao, Xiaojing Xuhumidified incubator at 37 °C with 5 % CO2. To induce p38 activity, cells were treated with 5 μM anisomycin (HY-18982, MCE) for 24 h according to previous study [23]. Public databases The GeneCards (https://www.genecards.org/)

(7) In Silico Prediction of EZHIP Post-Translational Modification Sites and Small-Molecule High-Throughput Screening for Quantitative EZHIP ModulationBrain Tumor Res TreatApril 30, 2026Jimin Moon, Jiwon Hwang, Chan ChungµM [23], A23187 (MCE, HY-N6687); 1 µM [24], Spermine (MCE, HY-B1777); 200 µM [25], Anisomycin (MCE, HY-18982); 5 µM [26], Forskolin (MCE, HY-15371); 10 µM [27], Phorbol 12-myristate 13-acetate, PMA (MCE, HY-18739);

(8) ADAM15 promotes the progression and metastasis of hepatocellular carcinoma by activating the JNK/p38 pathwayScientific ReportsApril 15, 2026Xu Junhui, Su Mengyun(1:5000, Servicebio, GB23301). JNK inhibitor (SP600125, HY-12041, MCE, America); JNK agonist (Anisomycin, HY-18982, MCE, America). The densities of the proteins were quantified with ImageJ software. Cell proliferation

(9) Pterostilbene attenuates lung ischemia-reperfusion injury: integrative insights from network pharmacology, molecular dynamics, and experimental validationFront PharmacolApril 1, 2026Haotian Bai, Heng Zhao, Jinteng Feng, Hongyi Wang, Yixing Li, Zhe Chen, Bin He, Chi Wang, Rui Gao, Rui Zhao, et al.and drug administration Pterostilbene (PTE, HY-N0828), LY294002 (LY, HY-10108), and Anisomycin (Ani, HY-18982) were all purchased from MedChemExpress (MCE, United States), and dissolved in dimethyl sulfoxide (DMSO,

(10) 40 Hz light flickering alleviates chronic pain via adenosine signaling in the retina-amygdala pathwayCell ResearchMarch 4, 2026Jiawang Chen, Tao Xu, Chenchen Zhang, Li Li, Yan He, Zhaoxia Sun, Jiasheng He, Zhimo Yao, Peng Cai, Yipeng Huang, et al.concentrations (0.05 mg/mL, 0.2 mg/mL, and 0.5 mg/mL) and vortexed for 30 s prior to injection. Anisomycin (HY-18982, MCE) was dissolved in 3 N HCl at 37 °C with continuous gentle agitation for 10 min to ensure complete

(11) Selenoprotein GPX3 regulates NADPH oxidase expression by inhibiting the MAPK signaling pathway and thereby attenuating the inflammatory response in renal ischemia-reperfusion injuryGenes & DiseasesMarch 1, 2026Jun Pei, Jie Zhang, Chengjun Yu, Jin Luo, Sheng Wen, Yi Hua, Guanghui WeiCat#APs0057), anti-JNK (Proteintech, Cat#28007-1-AP), and anti-p-JNK (ABclonal, Cat#AP0631). Anisomycin (Cat#HY-18982), a MAPK pathway activator, and dihydroethidium (Cat#HY-D0079) were purchased from MCE. TUNEL Andy Fluor™

(12) f-SPION-mediated magnetic stimulation induces reparative Schwann cell reprogramming via cytoskeletal dynamics - gated activation of Piezo1Journal of NanobiotechnologyFebruary 24, 2026Ting Liu, Mingxi Yang, Wantao Tian, Jingyan Ren, Laijin Lu, Yang Wangmagnetomechanical stimulation via the f-SPION–GMF interaction, followed by 0.2 μM anisomycin treatment (MCE, Cat. #HY-18982, Monmouth Junction, NJ, USA) for 12 h to inhibit protein synthesis-dependent responses. To investigate

(13) Linezolid‐mediated Prevention of Fibroblast Activation and Tissue Fibrosis via Mitochondrial Translation InhibitionArthritis & RheumatologyFebruary 13, 2026Xuezhi Hong, Yanhua Xiao, Haodong Qi, Shihao Zhu, Tim Filla, Andrea‐Hermina Györfi, Yi‐Nan Li, Meilin Xu, Langxian Zhi, Thuong Trinh‐Minh, et al.Scientific, Eschwege, Germany), and 10% FBS (10500‐064; Gibco), met‐free DMEM + 100 μg/mL anisomycin (ANS) (HY‐18982; MCE), or met‐free DMEM + 100 μg/mL ANS + 100 μM HPG (CLK‐1067‐25; Jena Bioscience, Jena, Germany) for

(14) Combined Effects of Puerarin and Adipose‐Derived Stem Cells on Alveolar Bone Preservation and Inflammation Control in Periodontitis Through p38MAPK ModulationThe Kaohsiung Journal of Medical SciencesFebruary 3, 2026Ting Yang, Xu Zhang, Liang‐Fu Zhangcounteracts puerarin‐induced osteogenic effects: Control (0.1% DMSO), anisomycin (25 μg/mL; MedChemExpress, HY‐18982; 30 min), and puerarin + anisomycin. In the puerarin + anisomycin group, puerarin (10−6 M; DMSO ≤ 0.1%)

(15) A MIF-p38-GSDMD inflammatory loop in keratinocytes underlies UVB-induced cutaneous lupusCell Death DisFebruary 2, 2026Chipeng Guo, Siweier Luo, Jigang Luo, Siyao Lu, Xiaomei You, Junlin Cao, Yufei Du, Haoran Lv, Hanzhi Liang, Le Wang, et al.for 24 or 48 h [33, 35]. To activate the ZAKα pathway, cells were exposed to 1 μM anisomycin (ANS, HY-18982, MCE) for 3 h [37]. For pathway inhibition studies, cells were pretreated with 10 μM SB203580 (S1863,

(16) proBDNF-SorCS2 Axis Suppresses Osteogenesis and Augments Inflammation of Human Periodontal Ligament Stem Cells in Inflammatory ConditionsInternational dental journalFebruary 1, 2026Pan L, Yang Y, Jia X, Zhao R, Wang Y, Guan X, Hou T.50 µg/mL for 24, 48, or 72 hours at 37 °C. For anisomycin, cells were treated with anisomycin (MCE, #HY-18982) at a concentration of 0.025, 0.05, 0.1, 0.2, 0.5, 1.0, 2.0, 4.0, and 8.0 µM for 48 hours at 37 °C.

(17) TKI-mediated inhibition of NLRP1 inflammasome restores erythropoiesis in DBA syndromeEMBO Molecular MedicineJanuary 9, 2026Juan M Lozano-Gil, Lola Rodríguez-Ruiz, Manuel Palacios, Jorge Peral, Susana Navarro, José L Fuster, Cristina Beléndez, Andrés Jérez, Laura Murillo-Sanjuán, Cristina Díaz-de-Heredia, et al.Peprotech" SCF,,"300-07, PeproTech" IL-3,,"200-03, PeproTech" Hemin,,"16009-13-5, Sigma-Aldrich" Anysomicin,,"HY-18982, MedChemExpress" MethoCult™,,"H4431, StemCell Technologies" Human AB plasma,,501973 (SeraCare) Human

(18) Ferulic acid in combination with ginsenoside Rb1 alleviates myocardial no-reflow by inhibiting platelet HMGB1 release and NET formationChinese MedicineJanuary 8, 2026Jia Li, Yue You, Yilin Wang, Jialu Zou, Shunli Xiao, Xiaojie Yin, Jing Xu, Fulong Liao, Huamin Zhang, Yun Youbought from Sigma-Aldrich (St Louis, MO, USA). SB203580 (HY-10256), U0126 (HY-12031A), and anisomycin (HY-18982) were purchased from MedChemExpress (New Jersey, USA). Percoll (17–0891-01) was purchased from Cytiva

(19) Mitochondrial CISD1 Modulates Microglial Metabolic Reprogramming to Drive Stress Susceptibility in MiceAdvanced ScienceJanuary 1, 2026Wanting Dong, Duo Liu, Songsen Fu, Jiaming Zhang, Xi Chen, Songqiang HuangmM), glucose (0.5%), actinomycin D (5 mg mL−1), triptolide (10 mM), and anisomycin (27.1 mg mL−1; MCE, HY‐18982). Tissue suspensions were homogenized using a Dounce homogenizer, passed through a 70 µm strainer, and

(20) Targeting p38 MAPK signaling pathway: Quercetin as a novel therapy for TMJ synovitisInternational journal of molecular medicineJanuary 1, 2026Cheng M, Guan Y, Xin X, Yi X, Liu Y.pretreated for 30 min with either the p38 MAPK activator anisomycin (10 μM; MedChemExpress; cat. no. HY-18982) or the inhibitor SB203580 (10 μM, HY-10256, MedChemExpress), followed by co-treatment with 40 μM quercetin

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Anisomycin from MedChemExpress

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Anisomycin from MedChemExpress

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