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Protein Biochemistry
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Nelfinavir
Nelfinavir from MedChemExpress
Be the first to write a review!
Citations:
(9)
Supplier Page
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MedChemExpress for
Nelfinavir
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Description
Nelfinavir (AG-1341) is a potent and orally bioavailable
HIV-1 protease
inhibitor (
K
i
=2 nM) for HIV infection. Nelfinavir is a broad-spectrum, anticancer agent
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Nelfinavir
Company
MedChemExpress
Price
$125.00
Supplier Page
View Company Product Page
Catalog Number
HY-15287
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
98.65%
Type
Chemical
Molecular Weight
567.78
Formula
C₃₂H₄₅N₃O₄S
Research Area
Infection; Cancer
Add to Compare List
MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (9)
(1)
Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution
Molecular Oncology
June 5, 2026
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska,
et al.
MedChemExpress
,
Carfilzomib
(
HY‐10455
);
MedChemExpress
,
VER‐155008
(
HY‐10941
);
MedChemExpress
,
Nelfinavir
(
HY‐15287
);
MedChemExpress
,
Nab‐paclitaxel
(
HY‐P99974
);
MedChemExpress
,
Gemcitabine
(
HY‐17026
);
MedChemExpress
,
(2)
Nelfinavir triggers ferroptosis by inducing ER stress mediated downregulation of GPX4/GSH system, upregulation of NRF2/HO-1 axis, and mitochondrial impairment in hepatocellular carcinoma cells
Cell Death Discov
October 6, 2025
Lei Zhang, Xuejun Wang
were initially dissolved in DMSO. The manufactures of the drugs are listed as follows: nelfinavir (
HY-15287
,
MCE
),
Chloroquine
(
HY-17589A
,
MCE
), Cycloheximide (HY-12320, MCE),
Sorafenib
(
HY-10201
,
MCE
),
RSL3
(3)
A genetically based computational drug repurposing framework for rapid identification of candidate compounds: application to COVID-19
medRxiv
January 14, 2025
Georgios Voloudakis, Kyung Min Lee, James M. Vicari, Wen Zhang, Daisy Hoagland, Sanan Venkatesh, Jiantao Bian, Marios Anyfantakis, Zhenyi Wu, Samir Rahman,
et al.
J6231403), retinol (Alfa Aesar, Cat # J6207903), and the aHIV
protease inhibitors
; nelfinavir (
MCE
, Cat #
HY-15287
) and saquinavir (
MCE
, Cat #
HY-17007
) were reconstituted in 100% DMSO. Stocks were further diluted in
(4)
Bardoxolone and bardoxolone methyl, two Nrf2 activators in clinical trials, inhibit SARS-CoV-2 replication and its 3C-like protease
Signal transduction and targeted therapy
May 29, 2021
Sun Q, Ye F, Liang H, Liu H, Li C, Lu R, Huang B, Zhao L, Tan W, Lai L.
(5)
Nelfinavir suppresses insulin signaling and nitric oxide production by human aortic endothelial cells: protective effects of thiazolidinediones
The Ochsner journal
March 1, 2013
Mondal D, Liu K, Hamblin M, Lasky JA, Agrawal KC.
(6)
The human immunodeficiency virus-1 protease inhibitor nelfinavir impairs proteasome activity and inhibits the proliferation of multiple myeloma cells in vitro and in vivo
Haematologica
July 1, 2012
Bono C, Karlin L, Harel S, Mouly E, Labaume S, Galicier L, Apcher S, Sauvageon H, Fermand JP, Bories JC,
et al
.
(7)
Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo
Clinical cancer research : an official journal of the American Association for Cancer Research
September 1, 2007
Gills JJ, Lopiccolo J, Tsurutani J, Shoemaker RH, Best CJ, Abu-Asab MS, Borojerdi J, Warfel NA, Gardner ER, Danish M,
et al
.
(8)
Viracept (nelfinavir mesylate, AG1343): a potent, orally bioavailable inhibitor of HIV-1 protease
Journal of medicinal chemistry
November 21, 1997
Kaldor SW, Kalish VJ, Davies JF 2nd, Shetty BV, Fritz JE, Appelt K, Burgess JA, Campanale KM, Chirgadze NY, Clawson DK,
et al
.
(9)
[Presence of conjugated catecholamines in the normal human amniotic fluid]
Archives internationales de physiologie et de biochimie
January 1, 1976
Bourdon V, Lecomte J, Juchmès J, Piret J.
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Nelfinavir from MedChemExpress
Supplier Page
View Company Product Page
$125.00
Product Specs
Company Info
Citations
Reviews
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