BML-277 from MedChemExpress

Product Specs
ItemBML-277
CompanyMedChemExpress
Price $66.00Supplier Page View Company Product Page
Catalog NumberHY-13946
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.74%
TypeChemical
Molecular Weight363.8
FormulaC₂₀H₁₄ClN₃O₂
Research AreaCancer

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(1) Activation of the MEK1-CHK2 axis in macrophages by Staphylococcus aureus promotes mitophagy, resulting in a reduction in bactericidal efficacyMol MedMay 29, 2025Xiaohu Wu, Xin Guan, Chubin Cheng, Zhantao Deng, Zeng Li, Yuanchen Ma, Yanjie Xie, Qiujian Zhengpostoperative Day 7: GDC-0973 (2 mg/kg, i.p., #HY-13064, MCE, USA), GDC-0973 + BML-277 (2 mg/kg, i.p., #HY-13946, MCE, USA), and LY3214996 (1 mg/kg, i.p., #HY-101494, MCE, USA) + BML-277. The control group received

(2) Large-scale characterization of drug mechanism of action using proteome-wide thermal shift assaysElifeNovember 11, 2024Jonathan G Van Vranken, Jiaming Li, Julian Mintseris, Ting-Yu Wei, Catherine M Sniezek, Meagan Gadzuk-Shea, Steven P Gygi, Devin K Schweppecompound,BS-181,MedChemExpress,HY-13266, Chemical compound,Erlotinib,MedChemExpress,HY-50896, Chemical compound,BML-277,MedChemExpress,HY-13946, Chemical compound,BMS-911543,MedChemExpress,HY-15270, Chemical compound,Givinostat,Cayman,11045, Chemical

(3) Checkpoint kinase inhibitors: SAR and radioprotective properties of a series of 2-arylbenzimidazolesJournal of medicinal chemistryMarch 24, 2005Arienti KL, Brunmark A, Axe FU, McClure K, Lee A, Blevitt J, Neff DK, Huang L, Crawford S, Pandit CR, et al.

(4) Configuration mixing in 56Co and 46Sc using (dPhysical review. C, Nuclear physicsOctober 1, 1993Crosson ER, Ludwig EJ, Bisenberger M, Hertenberger R, Hofer D, Kader H, Schiemenz P, Graw G, Eiró AM, Santos FD, et al.

(5) Oncogene PRR14 promotes breast cancer through activation of PI3K signal pathway and inhibition of CHEK2 pathwayCell death & diseaseJanuary 1, 0001"Ren X, Long M, Li Z, Wu B, Jin T, Tu C, Qi L, Yang M."China) and validated by STR DNA analysis. Chemicals including selective CHEK2 inhibitor BML-277 (BML, HY-13946, MCE)46, and genotoxic chemicals, including bleomycin (Bleo, HY-17565, MCE), etoposide (Eto, HY-13629,

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BML-277 from MedChemExpress

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BML-277 from MedChemExpress

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