Pomalidomide from MedChemExpress

Product Specs
ItemPomalidomide
CompanyMedChemExpress
Price $73.00Supplier Page View Company Product Page
Catalog NumberHY-10984
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.96%
TypeChemical
Molecular Weight273.24
Molecule NamePomalidomide
FormulaC13H11N3O4
Research AreaCancer

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(1) Targeted Degradation of Picornaviral 3C Protease via PROTACs Confers High Barrier to Viral Resistance and Broad-Spectrum Antiviral ActivityAdv Sci (Weinh)July 17, 2026Weilong Deng, Junyu Chen, Yingyue Pang, Yuanyuan Zhang, Siqian Chen, Guoliang You, Xiaoman Tian, Zhongxin Xu, Jing Wang, Luqing Shangtransfected cells were seeded into 12‐well plates and treated with 10 µM A8, 10 µM Pomalidomide (MCE, HY‐10984), 5 µM MLN4924 (MCE, HY‐70062), 5 µM TAK‐243 (MCE, HY‐100487), 5 µM Carfilzomib (MCE, HY‐10455), or

(2) A bulk cell heterozygous knock-in strategy for targeted protein degradationbioRxivMay 25, 2026Beibei Liu, Chao Qi, Tomoharu KanieBiological Materials). Compounds FKBP12 PROTAC dTAG-13 (HY-114421, MedChemExpress), Pomalidomide (HY-10984, MedChemExpress), HaloPROTAC3 (AOB36136, Aobious), were dissolved in dimethyl sulfoxide (DMSO) at a

(3) Development of PROTACs for targeted degradation of oncogenic TRK fusionsRSC Chemical BiologyApril 16, 2026Saurav Kumar, Jiewei Jiang, Mia S. Donald-Paladino, Joy Chen, Andrea Gutierrez, Alexander J. Federation, Frank Szulzewsky, Eric C. Holland, Fleur M. Ferguson, Behnam Nabet(Millipore Sigma, #901558), bafilomycin A1 (Cambridge Bioscience, #b0025) and pomalidomide (MedChemExpress, #HY-10984) were purchased from the indicated sources. Cell line culturing KM12 (kindly provided by the MD Anderson

(4) CAND1 and CAND2 drive CUL4 substrate receptor exchange with largely comparable biochemical efficiency, unlike their relative effects on CUL1StructureMarch 20, 2026Kankan Wang, Sebastian Kenny, Zhana Chagan, Lihong Li, Chittaranjan Das, Xing Liuproteins" MLN4924,MedChemExpress,Cat # HY-70062 CSN5i-3,MedChemExpress,Cat # HY-112134 Pomalidomide,MedChemExpress,Cat # HY-10984 IBG3,MedChemExpress,Cat # HY-160528 CR8,MedChemExpress,Cat # HY-18340 FlAsH-EDT2,Cayman Chemical,Cat

(5) Regulation of BCL11A DNA binding and expression in human erythrocyte precursor HUDEP-2 cellsbioRxivFebruary 12, 2026Meigen Yu, Puspa Das, John R. Horton, Jujun Zhou, Jisun Lee, Tingting Hong, Yue Lu, Marcos R. Estecio, Polina A. Iakova, Abhinav K. Jain, et al.DNA Technologies (IDT). Chemical compounds GSK3484862 (HY-135146), FTX6058 (HY-139400), pomalidomide (HY-10984) and lenalidomide (HY-A0003) were purchased from MedChemExpress. Compound EML741 was synthesized and

(6) Targeting BCL-XL for degradation synergizes with gemcitabine against cholangiocarcinomaBMC MedicineJanuary 30, 2026Qinghua Zeng, Yan Zhang, Yiwen Yang, Xin Liu, Xin Dong, Yongzhang Pan, Li Hu, Ao Zhang, Jian Yang, Qiuni Luo, et al.file 1). A1331852 (HY-19741), S63845 (HY-100741), ABT199 (HY-15531), QVD (HY-12305), pomalidomide (HY-10984), MG132 (HY-13259), doxorubicin (HY-15142), and gemcitabine (HY-17026) were obtained from MedChemExpress

(7) CAN-Scan: A multi-omic phenotype-driven precision oncology platform identifies prognostic biomarkers of therapy response for colorectal cancerCell Reports MedicineApril 15, 2025Shumei Chia, Justine Jia Wen Seow, Rafael Peres da Silva, Chayaporn Suphavilai, Niranjan Shirgaonkar, Maki Murata-Hori, Xiaoqian Zhang, Elena Yaqing Yong, Jiajia Pan, Matan Thangavelu Thangavelu, et al.HY-10981 6-Mercaptopurine,MedChemExpress,Cat# HY-13677 Pemetrexed,Tocris,Cat# 6185/50 Pomalidomide,MedChemExpress,Cat# HY-10984 Thalidomide,MedChemExpress,Cat# HY-14658 Thiotepa,MedChemExpress,Cat# HY-17574 Trametinib,MedChemExpress,Cat#

(8) Dual CARM1-and IKZF3-targeting: A novel approach to multiple myeloma therapy synergy between CARM1 inhibition and IMiDsMol Ther OncolMarch 20, 2025Ni W, Garg S, Chowdhury B, Sattler M, Sanchez D, Meng C, Akatsu T, Donovan KA, Qi J, Wang MY, et al.HY-A0003). Pomalidomide was purchased from Millipore Sigma (P0018-5MG) and MedChemExpress (Cat. No.: HY-10984). The agents, 070, 074, and MTG-3-141 (negative control compound), were synthesized by Dr. Sara Buhrlage

(9) Pomalidomide improves the effectiveness of CAR-T treatment in the relapsed and refractory multiple myeloma or B-cell leukemia/lymphoma with extramedullary diseaseBlood SciApril 1, 2024Zhao J, Yang H, Ge J, Li L, Yao Q, He S, Zhu Q, Ren R, Li C, Ma L, et al.K562 chronic myeloid leukemia cell line. The compound pomalidomide was procured from MedChemExpress (HY-10984; Monmouth Junction, New Jersey). It was then dissolved in dimethyl sulfoxide (DMSO) of cell culture

(10) Synergy between BRD9- and IKZF3-Targeting as a Therapeutic Strategy for Multiple MyelomaCancers (Basel)March 28, 2024Basudev Chowdhury, Swati Garg, Wei Ni, Martin Sattler, Dana Sanchez, Chengcheng Meng, Taisei Akatsu, Richard Stone, William Forrester, Edmund Harrington, et al.was purchased from Millipore Sigma (Burlington, MA, USA) (P0018-5MG) and MedChemExpress (Cat. No.: HY-10984). 2.2. Cell Lines and Cell Culture H929 and RPMI-8226 MM cell lines were obtained from Dr. Kenneth

(11) IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemiaNature cancerMay 1, 2022Aubrey BJ, Cutler JA, Bourgeois W, Donovan KA, Gu S, Hatton C, Perlee S, Perner F, Rahnamoun H, Theall ACP, et al.drugs were obtained from MedChemExpress: Thalidomide (MedChem Cat#HY-14658), Pomalidomide (MedChem Cat#HY-10984), Lenalidomide (MedChem Cat#HY-A0003), and Iberdomide/CC220 (MedChem Cat#HY-101291) were made into single-use

(12) Structural basis and regulation of the reductive stress responseCellOctober 14, 2021Manford AG, Mena EL, Shih KY, Gee CL, McMinimy R, Martínez-González B, Sherriff R, Lew B, Zoltek M, Rodríguez-Pérez F, et al.Pomalidomide treatment, TPEN was added at 2.5μM for 16hours and 10μM Pomalidomide (MedChemExpress, HY-10984) for 4 hours. Transfections and lentiviral packaging All siRNA transfections were performed with Lipofectamine

(13) Pomalidomide improves the function of CD133- or HER2-specific CAR T cellsBIOCELLJanuary 1, 2021ZHIXIONG WANG, NA RISU, JIAYU FU, HUI LIU, GUOMIN ZHOU, QIAN LIU, YAN ZOU, JIAXING TANG, LONG LI, XUEKAI ZHUbut the steps of nucleofection and drug selection were avoided. Pomalidomide was purchased from MCE (HY-10984, Monmouth Junction, NJ, USA) and dissolved in dimethyl sulfoxide (DMSO) at a concentration of 10 mM

(14) Tumour necrosis factor-α inhibits hepatic lipid deposition through GSK-3β/β-catenin signaling in juvenile turbot (Scophthalmus maximus L.)General and comparative endocrinologyMarch 1, 2016Liu D, Mai K, Zhang Y, Xu W, Ai Q.

(15) Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4Chemistry & biologyJune 18, 2015Lu J, Qian Y, Altieri M, Dong H, Wang J, Raina K, Hines J, Winkler JD, Crew AP, Coleman K, et al.

(16) Molecular mechanism of action of immune-modulatory drugs thalidomide, lenalidomide and pomalidomide in multiple myelomaLeukemia & lymphomaApril 1, 2013Zhu YX, Kortuem KM, Stewart AK.

(17) Pomalidomide shows significant therapeutic activity against CNS lymphoma with a major impact on the tumor microenvironment in murine modelsPloS oneJanuary 1, 2013Li Z, Qiu Y, Personett D, Huang P, Edenfield B, Katz J, Babusis D, Tang Y, Shirely MA, Moghaddam MF, et al.

(18) Immunomodulatory drug CC-5013 or CC-4047 and rituximab enhance antitumor activity in a severe combined immunodeficient mouse lymphoma modelClinical cancer research : an official journal of the American Association for Cancer ResearchAugust 15, 2005Hernandez-Ilizaliturri FJ, Reddy N, Holkova B, Ottman E, Czuczman MS.

(19) Enhancement of cytokine production and AP-1 transcriptional activity in T cells by thalidomide-related immunomodulatory drugsThe Journal of pharmacology and experimental therapeuticsJune 1, 2003Schafer PH, Gandhi AK, Loveland MA, Chen RS, Man HW, Schnetkamp PP, Wolbring G, Govinda S, Corral LG, Payvandi F, et al.

(20) [Phosphlipids and neutral lipids of the testis of the monkey as a function of sexual maturity]Comptes rendus des seances de la Societe de biologie et de ses filialesJanuary 1, 1976Tahiri-Zagret C, Clerc M.

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Pomalidomide from MedChemExpress

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Pomalidomide from MedChemExpress

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