ML347 from MedChemExpress

Product Specs
ItemML347
CompanyMedChemExpress
Price $73.00Supplier Page View Company Product Page
Catalog NumberHY-12274
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.94%
TypeChemical
Molecular Weight352.39
FormulaC₂₂H₁₆N₄O
Research AreaCancer

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(1) Recombinant BMP9 Reinforces Gut Vascular Barrier in Experimental ColitisBiomedicinesJanuary 28, 2026Shan Li, Xingyue Zhou, Yili Wang, Bingyue Yao, Siyuan Zhu, Ritian Lin, Qinjuan Sun, Jinlai Lu, Miao Hu, Wei Wang, et al.(20 ng/mL; Novoprotein, Suzhou, China, #C008), and ML347 (150 nM; MCE, Monmouth Junction, NJ, USA, #HY-12274). Plates were incubated under standard culture conditions (37 °C, 5% CO2, 95% humidity) for 12 h. The

(2) Sinomenine Ameliorated Microglial Activation and Neuropathic Pain After Chronic Constriction Injury Via TGF‐β1/ALK5/Smad3 Signalling PathwayJournal of Cellular and Molecular MedicineNovember 25, 2024Ling Ling, Min Luo, Haolin Yin, Yunyun Tian, Tao Wang, Bangjian Zhang, Li Yin, Yuehui Zhang, Jiang Bianmanner to examine the analgesic effects of SIN in mice. The ALK1 selective inhibitor ML347 (100 ng, HY‐12274; MedChemExpress, NJ, USA) or ALK5 selective inhibitor ALK5 inhibitor SB‐505124 (100 ng, HY‐13521; MedChemExpress,

(3) Targeting Fascin1 maintains chondrocytes phenotype and attenuates osteoarthritis developmentBone ResearchSeptember 4, 2024Panpan Yang, Yun Xiao, Liangyu Chen, Chengliang Yang, Qinwei Cheng, Honghao Li, Dalin Chen, Junfeng Wu, Zhengquan Liao, Changsheng Yang, et al.analysis. For the drug treatments of OA in mice, 10 μL of drugs: 20 mmol/L LDN-193719 (Cat. No. #: HY-12274, MedChemExpress), 10 mmol/L NP, were injected once a week via intra-articular administration into the

(4) Dual roles of TGF-β signaling in the regulation of dental epithelial cell proliferationJournal of molecular histologyFebruary 1, 2021Zhang H, Zhan Y, Zhang Y, Yuan G, Yang G.

(5) Synthesis and structure-activity relationships of a novel and selective bone morphogenetic protein receptor (BMP) inhibitor derived from the pyrazolo[1.5-a]pyrimidine scaffold of dorsomorphin: the discovery of ML347 as an ALK2 versus ALK3 selective MLPCN probeBioorganic & medicinal chemistry lettersJune 1, 2013Engers DW, Frist AY, Lindsley CW, Hong CC, Hopkins CR.

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ML347 from MedChemExpress

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