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Protein Biochemistry
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Amonafide
Amonafide from MedChemExpress
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Citations:
(5)
Supplier Page
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MedChemExpress for
Amonafide
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Description
Amonafide is a
topoisomerase II
inhibitor and DNA intercalator that induces apoptotic signaling by blocking the binding of Topo II to DNA
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Amonafide
Company
MedChemExpress
Price
$105.00
Supplier Page
View Company Product Page
Catalog Number
HY-10982
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.92%
Type
Chemical
Molecular Weight
283.33
Formula
C₁₆H₁₇N₃O₂
Research Area
Cancer
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (5)
(1)
Amonafide Targeting NTSR1‐PI3K/AKT/mTOR Signaling Attenuates Vascular Remodeling in Pulmonary Arterial Hypertension
J Am Heart Assoc
May 14, 2026
Yong‐Jian Zhu, Jie‐Jian Kou, Ya‐Cong Bo, Meng‐Jie Zhang, Xin Fan, Lu‐Ling Zhao, Yi Yan, Hong‐Da Zhang, Wen‐Hui Wu, Ping Yuan,
et al.
saline. From day 15,
rats
were administered daily
intraperitoneal injection
of amonafide (3 mg/kg,
HY‐10982
;
MedChemExpress
, Shanghai, China) or equivalent volumes of sterile saline. For the SuHx‐induced
mice
(2)
Drug repositioning for pan-cancers of the digestive system: Identification of amonafide and BX795 as potential therapeutics via integrative Omics analysis
PLoS One
June 16, 2025
Weidong Liu, Jiaying Gao, Shuqiang Ren, Buhe Nashun, Fei Gao
viability of HT29 and
HepG2 cells
were evaluated using the CCK8 kit (MI00615A, MISHU, China).
Amonafide
(
HY-10982
) and
BX795
(
HY-10514
) were purchased from Shanghai
MedChemExpress
Bio-Technology Co., Ltd. The drugs
(3)
Amonafide: a potential role in treating acute myeloid leukemia
Expert opinion on investigational drugs
July 1, 2011
Allen SL, Lundberg AS.
(4)
In vitro activity of amonafide against primary human tumors compared with the activity of standard agents
Investigational new drugs
June 1, 1988
Ajani JA, Baker FL, Spitzer G.
(5)
In vitro toxicity and DNA cleaving capacity of benzisoquinolinedione (nafidimide; NSC 308847) in human leukemia
Cancer research
February 15, 1987
Andersson BS, Beran M, Bakic M, Silberman LE, Newman RA, Zwelling LA.
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Amonafide from MedChemExpress
Supplier Page
View Company Product Page
$105.00
Product Specs
Company Info
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